Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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COVID-19 Patients Benefitting From Remdesivir for Improved Survival: A Neural Network-Based Approach.

Conflicting results from randomized trials regarding the efficacy of remdesivir for COVID-19 have been reported. We aimed to develop a neural network (NN) to identify COVID-19 patients who would derive the greatest survival benefit from remdesivir. This multicenter observational study included adults hospitalized for COVID-19 between February 2020 and February 2021. A derivation cohort from Hospit...

Mar 1 2025 40059457

PsychBench: A comprehensive and professional benchmark for evaluating the performance of LLM-assisted psychiatric clinical practice

The advent of Large Language Models (LLMs) offers potential solutions to address problems such as shortage of medical resources and low diagnostic consistency in psychiatric clinical practice. Despite this potential, a robust and comprehensive benchmarking framework to assess the efficacy of LLMs in authentic psychiatric clinical environments is absent. This has impeded the advancement of specia...

SafeAuto: Knowledge-Enhanced Safe Autonomous Driving with Multimodal Foundation Models

Traditional autonomous driving systems often struggle to integrate high-level reasoning with low-level control, resulting in suboptimal and sometime...

Learning Vision-Based Neural Network Controllers with Semi-Probabilistic Safety Guarantees

Ensuring safety in autonomous systems with vision-based control remains a critical challenge due to the high dimensionality of image inputs and the ...

Generating patient cohorts from electronic health records using two-step retrieval-augmented text-to-SQL generation

Clinical cohort definition is crucial for patient recruitment and observational studies, yet translating inclusion/exclusion criteria into SQL queri...

Beware of Your Po! Measuring and Mitigating AI Safety Risks in Role-Play Fine-Tuning of LLMs

Role-playing enables large language models (LLMs) to engage users in immersive and personalized interactions, but it also introduces significant saf...

Medical Hallucinations in Foundation Models and Their Impact on Healthcare

Foundation Models that are capable of processing and generating multi-modal data have transformed AI's role in medicine. However, a key limitation o...

3D Nephrographic Image Synthesis in CT Urography with the Diffusion Model and Swin Transformer

Purpose: This study aims to develop and validate a method for synthesizing 3D nephrographic phase images in CT urography (CTU) examinations using a ...

Repurposing the scientific literature with vision-language models

Leading vision-language models (VLMs) are trained on general Internet content, overlooking scientific journals' rich, domain-specific knowledge. Tra...

Adaptive Shielding via Parametric Safety Proofs

A major challenge to deploying cyber-physical systems with learning-enabled controllers is to ensure their safety, especially in the face of changin...

Zero-Shot Defense Against Toxic Images via Inherent Multimodal Alignment in LVLMs

Large Vision-Language Models (LVLMs) have made significant strides in multimodal comprehension, thanks to extensive pre-training and fine-tuning on ...

Enhancing Hepatopathy Clinical Trial Efficiency: A Secure, Large Language Model-Powered Pre-Screening Pipeline

Background: Recruitment for cohorts involving complex liver diseases, such as hepatocellular carcinoma and liver cirrhosis, often requires interpret...

A Systematic Review of Open Datasets Used in Text-to-Image (T2I) Gen AI Model Safety

Novel research aimed at text-to-image (T2I) generative AI safety often relies on publicly available datasets for training and evaluation, making the...

Shapley Value-based Approach for Redistributing Revenue of Matchmaking of Private Transactions in Blockchains

In the context of blockchain, MEV refers to the maximum value that can be extracted from block production through the inclusion, exclusion, or reord...

CurricuVLM: Towards Safe Autonomous Driving via Personalized Safety-Critical Curriculum Learning with Vision-Language Models

Ensuring safety in autonomous driving systems remains a critical challenge, particularly in handling rare but potentially catastrophic safety-critic...

ThinkGuard: Deliberative Slow Thinking Leads to Cautious Guardrails

Ensuring the safety of large language models (LLMs) is critical as they are deployed in real-world applications. Existing guardrails rely on rule-ba...

Investigating the Impact of Quantization Methods on the Safety and Reliability of Large Language Models

Large Language Models (LLMs) have emerged as powerful tools for addressing modern challenges and enabling practical applications. However, their com...

SATA: Safe and Adaptive Torque-Based Locomotion Policies Inspired by Animal Learning

Despite recent advances in learning-based controllers for legged robots, deployments in human-centric environments remain limited by safety concerns...

SEA: Low-Resource Safety Alignment for Multimodal Large Language Models via Synthetic Embeddings

Multimodal Large Language Models (MLLMs) have serious security vulnerabilities.While safety alignment using multimodal datasets consisting of text a...

LLM Safety for Children

This paper analyzes the safety of Large Language Models (LLMs) in interactions with children below age of 18 years. Despite the transformative appli...

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