Clinical Trials

Robot-Assisted Nephrectomy Using the Newly Developed Single-Port Robotic Surgical System: A Feasibility Study in Porcine Model.

To evaluate the feasibility and safety of the single-port robotic platform by performing nephrectomy in live porcine model. Robotic nephrectomy was performed on sample group of five gilts using the single-port robotic system. The continuous vital signs of all gilts were monitored throughout the operation to examine the safety of the operation. Data regarding surgical complications and technica...

Machine Learning Classifier Models Can Identify Acute Respiratory Distress Syndrome Phenotypes Using Readily Available Clinical Data.

Two distinct phenotypes of acute respiratory distress syndrome (ARDS) with differential clinical outcomes and responses to randomly assigned treatment have consistently been identified in randomized controlled trial cohorts using latent class analysis. Plasma biomarkers, key components in phenotype identification, currently lack point-of-care assays and represent a barrier to the clinical impleme...

Dynamic impact of transfusion ratios on outcomes in severely injured patients: Targeted machine learning analysis of the Pragmatic, Randomized Optimal Platelet and Plasma Ratios randomized clinical trial.

BACKGROUND: Massive transfusion protocols to treat postinjury hemorrhage are based on predefined blood product transfusion ratios followed by goal-dir...

Quantification of Fluid Resolution and Visual Acuity Gain in Patients With Diabetic Macular Edema Using Deep Learning: A Post Hoc Analysis of a Randomized Clinical Trial.

IMPORTANCE: Large amounts of optical coherence tomographic (OCT) data of diabetic macular edema (DME) are acquired, but many morphologic features have...

A Randomized Controlled Trial of an Intelligent Robotic Response to Joint Attention Intervention System.

Although there has been growing interest in utilizing robots for intervention in autism spectrum disorder (ASD), there have been very few controlled t...

[Study on precise mechanism of Chinese patent medicine from perspective of activating data].

Traditional Chinese medicine(TCM) syndrome differentiation and treatment has a characteristic and advantageous efficacy in the prevention and treatmen...

Wavelet Spectral Time-Frequency Training of Deep Convolutional Neural Networks for Accurate Identification of Micro-Scale Sharp Wave Biomarkers in the Post-Hypoxic-Ischemic EEG of Preterm Sheep.

Neonatal hypoxic-ischemic encephalopathy (HIE) evolves over different phases of time during recovery. Some neuroprotection treatments are only effecti...

Deep Learning based Quantification of Ovary and Follicles using 3D Transvaginal Ultrasound in Assisted Reproduction.

Quantification of ovarian and follicular volume and follicle count are performed in clinical practice for diagnosis and management in assisted reprodu...

Outcomes of a Robot-Assisted Social-Emotional Understanding Intervention for Young Children with Autism Spectrum Disorders.

This study is a randomized control trial aimed at testing the role of a human-assisted social robot as an intervention mediator in a socio-emotional u...

Effects of trunk stabilization training robot on postural control and gait in patients with chronic stroke: a randomized controlled trial.

Our study aimed to confirm the therapeutic effects of using a trunk stabilization training robot (3DBT-33) in patients with chronic stroke. A total of...

Robot-Assisted Cortical Bone Trajectory Insertion of Pedicle Screws: 2-Dimensional Operative Video.

Robot-assisted pedicle screw insertion has been slowly gaining popularity in the spine surgery community. In previous studies, robotics has been shown...

Autonomous Systems in Anesthesia: Where Do We Stand in 2020? A Narrative Review.

As most of us are aware, almost every facet of our society is becoming, for better or worse, progressively more technology-dependent. Technological ad...

Distinct subtypes of inhibitory interneurons differentially promote the propagation of rate and temporal codes in the feedforward neural network.

Sensory information is believed to be encoded in neuronal spikes using two different neural codes, the rate code (spike firing rate) and the temporal ...

Effect of a Machine Learning-Derived Early Warning System for Intraoperative Hypotension vs Standard Care on Depth and Duration of Intraoperative Hypotension During Elective Noncardiac Surgery: The HYPE Randomized Clinical Trial.

IMPORTANCE: Intraoperative hypotension is associated with increased morbidity and mortality. A machine learning-derived early warning system to predic...

Human adipose-derived mesenchymal stem cell-based medical microrobot system for knee cartilage regeneration in vivo.

Targeted cell delivery by a magnetically actuated microrobot with a porous structure is a promising technique to enhance the low targeting efficiency ...

The reactome pathway knowledgebase.

The Reactome Knowledgebase (https://reactome.org) provides molecular details of signal transduction, transport, DNA replication, metabolism and other ...

Efficacy of an Automated Robotic Cleaning Device for Compounding Pharmacies.

Compounded medicinal products should be prepared using an appropriate quality-assurance system. Cleaning and disinfection, as part of this system, are...

Future Vision 2020 and Beyond-5 Critical Trends in Eye Research.

Ophthalmology has been at the forefront of many innovations in basic science and clinical research. The randomized prospective multicenter clinical tr...

Machine learning versus traditional risk stratification methods in acute coronary syndrome: a pooled randomized clinical trial analysis.

Traditional statistical models allow population based inferences and comparisons. Machine learning (ML) explores datasets to develop algorithms that d...

Dairy Safety Prediction Based on Machine Learning Combined with Chemicals.

BACKGROUND: Dairy safety has caused widespread concern in society. Unsafe dairy products have threatened people's health and lives. In order to improv...