Clinical Trials

Towards Phenotyping of Clinical Trial Eligibility Criteria.

BACKGROUND: Medical plaintext documents contain important facts about patients, but they are rarely available for structured queries. The provision of structured information from natural language texts in addition to the existing structured data can significantly speed up the search for fulfilled inclusion criteria and thus improve the recruitment rate.

Comparative Analysis of Algorithmic Approaches for Auto-Coding with ICD-10-AM and ACHI.

Clinical coding is done using ICD-10-AM (International Classification of Diseases, version 10, Australian Modification) and ACHI (Australian Classification of Health Interventions) in acute and sub-acute hospitals in Australia for funding, insurance claims processing and research. The task of assigning a code to an episode of care is a manual process. This has posed challenges due to increase set ...

Effects of robot-assisted therapy on upper extremity function and activities of daily living in hemiplegic patients: A single-blinded, randomized, controlled trial.

BACKGROUND: Many robots can induce passive movements and passive resistance movements to facilitate recovery of upper-extremity function, but it is ra...

Machine-Learning Prediction of Drug-Induced Cardiac Arrhythmia: Analysis of Gene Expression and Clustering.

A marked delay in the electrical repolarization of heart ventricles is characterized by prolongation of the Q-T wave (QT) interval on a surface electr...

Comparison of Two Different Volumes of Ropivacaine Used in Nerve Stimulator Guided Inter-scalene Block for Arthroscopic Shoulder Surgery - A Randomized Controlled Trial.

BACKGROUND: This study was conducted to compare the analgesic efficacy of 10 ml versus 20 mL of 0.5% ropivacaine in nerve stimulator guided interscale...

Addition of Dexmedetomidine to Ropivacaine in Subcostal Transversus Abdominis Plane Block Potentiates Postoperative Analgesia among Laparoscopic Cholecystectomy Patients: A Prospective Randomized Controlled Trial.

CONTEXT: Laparoscopic cholecystectomy is associated with moderate intensity postoperative pain especially in the early postoperative period. Transvers...

Comparison between Colloid Preload and Coload in Bone Cement Implantation Syndrome under Spinal Anesthesia: A Randomized Controlled Trial.

BACKGROUND: Bone cement implantation syndrome (BCIS) is characterized by hypoxia hypotension cardiac arrest. There is not any research that investigat...

Identifying reports of randomized controlled trials (RCTs) via a hybrid machine learning and crowdsourcing approach.

OBJECTIVES: Identifying all published reports of randomized controlled trials (RCTs) is an important aim, but it requires extensive manual effort to s...

Effects of nefopam on emergence agitation after general anesthesia for nasal surgery: A prospective, randomized, and controlled trial.

BACKGROUND: Emergence agitation (EA) occurs frequently after nasal surgery. N-methyl-D-aspartate (NMDA) receptor antagonists and analgesics, such as f...

Slow Versus Fast Robot-Assisted Locomotor Training After Severe Stroke: A Randomized Controlled Trial.

BACKGROUND AND PURPOSE: Robot-assisted locomotor training on a bodyweight-supported treadmill is a rehabilitation intervention that compels repetitive...

On the Safety of Machine Learning: Cyber-Physical Systems, Decision Sciences, and Data Products.

Machine learning algorithms increasingly influence our decisions and interact with us in all parts of our daily lives. Therefore, just as we consider ...

Robotic Assistance for Training Finger Movement Using a Hebbian Model: A Randomized Controlled Trial.

BACKGROUND: Robots that physically assist movement are increasingly used in rehabilitation therapy after stroke, yet some studies suggest robotic assi...

Randomized, sham-controlled trial based on transcranial direct current stimulation and wrist robot-assisted integrated treatment on subacute stroke patients: Intermediate results.

The main goal of this study is to analyse the effects of combined transcranial direct current stimulation (tDCS) and wrist robot-assisted therapy in s...

Applying a soft-robotic glove as assistive device and training tool with games to support hand function after stroke: Preliminary results on feasibility and potential clinical impact.

Recent technological developments regarding wearable soft-robotic devices extend beyond the current application of rehabilitation robotics and enable ...

Initial experience with a robotically operated video optical telescopic-microscope in cranial neurosurgery: feasibility, safety, and clinical applications.

OBJECTIVE The move toward better, more effective optical visualization in the field of neurosurgery has been a focus of technological innovation. In t...

Psychophysiological resources and reserves for increasing flight safety.

The diirectins and ways of ostcgiogtsuikigucak health resources of pilot in order to ensure his professional safety are discussed. The author analyz t...

PHARMACOKINETICS AND BIOEQUIVALENCE STUDIES OF TWO NIMESULIDE 100 mg TABLETS: UNIT DOSE, RANDOMIZED-SEQUENCE, TWO-WAY CROSSOVER STUDY IN HEALTHY VOLUNTEERS OF PAKISTANI POPULATION.

Single centered crossover, two cycles volunteer study was performed on 12 healthy male volunteers. Both reference and test, immediate release nimesuli...

High-Throughput Classification of Radiographs Using Deep Convolutional Neural Networks.

The study aimed to determine if computer vision techniques rooted in deep learning can use a small set of radiographs to perform clinically relevant i...

Factors Associated with HIV Testing Among Participants from Substance Use Disorder Treatment Programs in the US: A Machine Learning Approach.

HIV testing is the foundation for consolidated HIV treatment and prevention. In this study, we aim to discover the most relevant variables for predict...

Further Development of a Robotic-Assisted Transfer Device.

The task of performing transfers, such as from a wheelchair to a bed, has a high risk of injury to both the caregiver and the person being transferre...