Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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The Effectiveness of Artificial Intelligence in Undergraduate Health Professions Education: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

BACKGROUND: Health professions education faces increasing challenges from rising health care complexity, pedagogical shifts, and constrained curricular space, and rapidly expanding knowledge and technological advances. While artificial intelligence (AI) shows promise for transforming health professions education, evidence of its effectiveness remains unclear. OBJECTIVE: This study synthesized evid...

May 5 2026 42085678

VR-H2Safe: a VR-based hydrogen vehicle safety & efficiency optimization platform with V2X integration.

Hydrogen vehicles are facing significant challenges, including safety risks in the event of leakage, high costs associated with physical testing, and fuel cell inefficiency under dynamic conditions; to address these concerns, we propose VR-H2Safe, a cyber-physical platform that combines high-fidelity simulation, physics-informed reinforcement learning (RL), and secure vehicle-to-everything (V2X) c...

May 5 2026 42086653
Evaluating the clinical safety of large language models in oral cancer-related patient communication: a repeated-prompt observational study.

BACKGROUND: As patients increasingly consult large language models (LLMs) for health-related information, evaluating the clinical safety of AI-generat...

May 5 2026 42087133
Utilizing generative artificial intelligence to create simulated patient for history taking in gynecology.

INTRODUCTION: This study aimed to evaluate the effectiveness of a generative artificial intelligence based simulated patient model in improving gyneco...

May 4 2026 42083027
When AI Colludes: Clinical Reliability of Training and Preference Data as a Trustworthy-AI Criterion.

BACKGROUND: Research on artificial intelligence (AI) and mental health has focused largely on harms at deployment, including chatbot safety, sycophanc...

May 4 2026 42076921
Augmented Reality and Artificial Intelligence for the Assessment and Rehabilitation of Spatial Neglect: A Systematic Review.

BACKGROUND AND PURPOSE: Augmented reality (AR) and artificial intelligence (AI) have been applied to the assessment and rehabilitation of post-stroke ...

May 4 2026 42080328
Expert Evaluation of the Perceived Accuracy, Relevance, and Safety of Large Language Model-Generated Patient Information in Geriatrics: Cross-Condition Study.

BACKGROUND: Large language models (LLMs) are increasingly used to generate patient-oriented medical information. In geriatrics, such information must ...

May 4 2026 42081273
Machine Learning Prediction and Reducing Overdoses With Electronic Health Record Nudges (mPROVEN) in the Primary Care Setting: Protocol for a Cluster Randomized Controlled Trial.

BACKGROUND: Opioid overdose remains a leading cause of preventable death in the United States. Existing approaches to identify individuals at elevated...

May 4 2026 42081274
Physician Perspectives on ChatGPT-4o as a Patient Resource for Abdominal Cancer Surgeries: Cross-Sectional Survey.

BACKGROUND: Artificial intelligence (AI) models are being increasingly integrated into clinical care. Moreover, the availability of publicly accessibl...

May 4 2026 42081743
AI in Clinical Decision Support Systems: Promising Applications and Strategies for Managing Data Challenges.

The translation of big data analytics and artificial intelligence (AI) into clinical decision support systems (CDSSs) has advanced from proof of conce...

May 4 2026 42081797
Understanding how language barriers in the paediatric emergency care setting influences safety of care delivery: a scoping review.

BACKGROUND: Communication in a family's primary language can support safe care. Vital steps within the care delivery process are contingent on success...

May 4 2026 42082339
Randomized controlled trial comparing AI-assisted digital and conventional orthodontics: Superior PAR reduction and occlusal outcomes.

BACKGROUND: Advances in digital orthodontics and artificial intelligence (AI) planning have the potential to enhance treatment precision, but randomiz...

May 4 2026 42081476
GPT-5-assisted versus expert surgeon refractive planning in smooth incision lenticule keratomileusis (SILK): comparative analysis and visual outcomes.

PURPOSE: To assess the performance of GPT-5 in refractive surgery planning by comparing its recommendations with expert surgeons and reporting visual ...

May 2 2026 42068428
Impact of a real-time automatic quality control system for magnetically controlled capsule gastroscopy: a multicenter randomized controlled trial.

BACKGROUND: Quality control can reduce variations in operators' performance conducting magnetically controlled capsule gastroscopy (MCCG). However, an...

May 2 2026 42069608
Prognostic Modeling Based on Post-Endovascular Thrombectomy Systolic Blood Pressure Trajectories Using Explainable Artificial Intelligence: A Secondary Analysis of the OPTIMAL-BP Trial.

Blood pressure (BP) management following successful reperfusion after endovascular thrombectomy (EVT) is critical in achieving favorable clinical outc...

May 2 2026 42067698
Effectiveness of Patent Foramen Ovale Occlusion Devices Versus Medical Therapy: An Indirect Comparison Based on Reconstructed Individual Patient Data.

BACKGROUND: Percutaneous closure of patent foramen ovale (PFO) reduces the risk of recurrent stroke in selected patients with cryptogenic stroke. Howe...

May 1 2026 42070674
Fiducial Confidence Intervals for Agreement Measures Among Raters Under a Generalized Linear Mixed Effects Model.

A generalization of the classical concordance correlation coefficient (CCC) is considered under a three-level design where multiple raters rate every ...

May 1 2026 42068150
Automatic Mediation Analysis Under Measurement Error Via Bayesian Machine Learning.

This paper considers the problem of causal mediation analysis (CMA) when the outcome, mediator, or both are modeled as latent variables that are measu...

May 1 2026 42063392
A Bilingual AI-Based Chatbot for Nutrition Education in a Food Is Medicine Intervention for High-Risk Pregnant Women: Design and Development Study.

BACKGROUND: Conversational agents (artificial intelligence [AI]-based chatbots) offer a novel approach to health interventions by providing personaliz...

May 1 2026 42066287
An Electromagnetic Navigation Surgical Robotic System (ENSRS) for Transthoracic Puncture of Small Pulmonary Nodules.

OBJECTIVE: To address the limitations of traditional CT-guided pulmonary nodule interventions, such as excessive radiation exposure, prolonged procedu...

May 1 2026 41056176
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