Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Showing 561-580 of 6,112 articles

Observational study of predictors and outcomes of lung cancer in never-smokers in the UK (OLIVE): study protocol.

INTRODUCTION: Lung cancer is commonly associated with smoking. However, if considered separately, lung cancer in never-smokers (LCINS) is the seventh most common cause of cancer-related death worldwide. Expanding the limited understanding of LCINS, especially in the UK, is crucial to improving diagnosis. METHODS AND ANALYSIS: We will establish a retrospective and prospective UK multicentre observa...

Jun 9 2026 42264884

Simulation-Enhanced Learning in Nuclear Medicine: Counterpoint.

Simulation-based education has become widely embedded in health professional training and is increasingly positioned as a solution to clinical placement capacity constraints, patient safety imperatives, and growing procedural complexity. Yet the rapid expansion of simulation in nuclear medicine technologist education carries under-recognized risks. Evidence frequently demonstrates gains in confide...

Jun 9 2026 42264900
Comparative evaluation and selection of optimal QSAR-based machine learning model for liver toxicity prediction.

Drug induced liver toxicity remains the most common cause of acute liver failure. Conventional toxicity detection relies on resource-intensive in vivo...

Jun 9 2026 42265490
Predictors of Detectable Viral Load among Adolescents with HIV in Low Resource Settings who are Receiving Care in Youth-Friendly Clinics.

OBJECTIVE: Adolescents with HIV (AWH) have higher rates of detectable viral loads (DVL) than adults. We sought to identify clinical and psychosocial p...

Jun 9 2026 42262345
Generative Artificial Intelligence Chatbots for Parental Guidance in Pediatric Orthopaedics: A Pilot Feasibility Study.

BACKGROUND: Parents of children with pediatric orthopaedic conditions frequently have questions after their clinic visit, and a reliable postconsultat...

Jun 9 2026 42256001
Bias, External Validation, and Real-World Implementation of Artificial Intelligence Models in Cardiovascular Medicine.

Artificial intelligence (AI) and machine learning (ML) have demonstrated strong diagnostic and prognostic performance across cardiovascular medicine. ...

Jun 8 2026 42264287
Process Improvement Before Artificial Intelligence and Automation: Building Trust With the Understand-Transform-Sustain Framework.

Artificial intelligence (AI) and automation are rapidly transforming health care, yet their integration into clinical workflows often falls short owin...

Jun 8 2026 42291022
Acanthamoeba Keratitis: Recent Advances in Diagnosis and Management.

PURPOSE: To review recent advances in the diagnosis and management of acanthamoeba keratitis (AK), emphasizing clinically relevant developments from t...

Jun 8 2026 42348670
Low Rates of Fibrosis in Eyes Treated with the Port Delivery Platform with Ranibizumab or with Monthly Ranibizumab in the Archway Trial.

PURPOSE: To evaluate the proportion of eyes with fibrosis in the Archway neovascular age-related macular degeneration trial, which compared efficacy a...

Jun 8 2026 42473439
Decision tree with randomized grid search-based hyperparameter tuning and optimal feature scaling for diabetes diagnosis.

BACKGROUND: Diabetes is a chronic condition that arises when the body cannot effectively regulate blood glucose levels, either due to insufficient ins...

Jun 8 2026 42260338
Artificial intelligence in traumatic stress treatment: The TRUST framework for ethical development, clinical applications, and research advancement.

Posttraumatic stress disorder (PTSD) and depression are common diagnoses following traumatic events, with several available evidence-based interventio...

Jun 8 2026 42260964
AI-based virtual patient training for clinical communication skills in dental undergraduates: A randomized controlled mixed methods study.

INTRODUCTION: Effective clinical communication is a core competency in dental education, yet traditional teaching methods often fail to provide authen...

Jun 8 2026 42258188
Unique Digital Images as Incentives in Clinical Trials: A Digital Shift Toward Meaningful Participation.

Incentivization in clinical trial participation can be challenging, with many studies failing to meet recruitment or retention goals despite tradition...

Jun 8 2026 42258364
360° Video-Based Virtual Reality for Preparing Medical Students for Body Donor Dissection: Randomized Controlled Trial.

BACKGROUND: Body donor dissection is fundamental to medical education but often induces anxiety and emotional distress in students, potentially impact...

Jun 8 2026 42258369
The emerging role of coronary computed tomography for prevention of cardiovascular disease in asymptomatic individuals.

The persistent global rise in atherosclerotic cardiovascular disease (ASCVD) challenges the effectiveness of current risk factor-based algorithms in p...

Jun 8 2026 42258629
Auricular Point Acupressure Self-Management (APA-SM) program for chronic musculoskeletal pain among rural populations: a protocol for a pragmatic, randomized controlled trial.

INTRODUCTION: Chronic musculoskeletal pain (CMP) is a leading cause of incurred personal healthcare costs and disability in the USA. It disproportiona...

Jun 8 2026 42259555
Risk and liability in the deployment of AI systems for surgery: a SAGES white paper.

BACKGROUND: Artificial intelligence (AI) is increasingly utilized in surgical care for decision support, operative planning, intraoperative guidance, ...

Jun 8 2026 42260175
Explainable AI reveals squamous histology and U-shaped PD-L1 patterns as primary subgroup predictors of neoadjuvant and perioperative immunotherapy benefit in NSCLC: a machine learning analysis.

BACKGROUND: The introduction of neoadjuvant and perioperative immunotherapy has broadened treatment options for resectable non-small cell lung cancer ...

Jun 6 2026 42249154
Multimodal Artificial Intelligence Prediction of Abiraterone Efficacy in Two STAMPEDE Phase 3 Trials of Non-Metastatic Very High-Risk Prostate Cancer.

BACKGROUND: Long-term androgen deprivation therapy (LT-ADT) with radiotherapy is standard-of-care for high-risk localized prostate cancer, with abirat...

Jun 5 2026 42250604
Fully Automated Free-Breathing Cardiac MRI at 3T: A Prospective Randomized Study of Image Quality, Efficiency, and Workflow Burden.

BACKGROUND: Automation in cardiac magnetic resonance (CMR) scans holds the potential to improve examination efficiency and workflow consistency. Prosp...

Jun 5 2026 42250883
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