Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Multi-task adversarial learning detects intersectional algorithmic bias in AI recruitment systems.

With the widespread application of artificial intelligence in recruitment, algorithmic bias issues have become increasingly prominent, seriously threatening social fairness and job seekers' rights. Addressing the limitations of existing bias detection methods in detection granularity, fairness assessment, and interpretability, this study proposes a deep learning-based algorithmic bias detection fr...

May 20 2026 42162118

TFRC-mediated immune exclusion as a therapeutic vulnerability in cervical cancer: A comprehensive analysis based on the cancer immunoediting process.

BACKGROUND: Advanced and recurrent cervical cancer (CC) remains a clinical challenge due to limited therapeutic options and a poor 5-year survival rate (<20%). While immunotherapy has reshaped the treatment landscape, primary resistance driven by immune exclusion often limits its efficacy. This study aims to identify the key molecular determinants governing T-cell infiltration and to develop a rob...

May 19 2026 42202548
Accuracy, Readability, and Clinical Applicability of AI-Generated Breastfeeding Education Brochures: A Mixed-Methods Evaluation.

BACKGROUND: Generative artificial intelligence (AI) is increasingly used in health communication and nursing education; however, its clinical reliabil...

May 19 2026 42157505
Multicenter validation and randomized crossover reader evaluation of deep learning-assisted tri-sequence three-dimensional MRI segmentation for hypopharyngeal tumor.

BACKGROUND AND PURPOSE: Accurate MRI-based target delineation for hypopharyngeal squamous cell carcinoma (HPSCC) is clinically important but expertise...

May 19 2026 42162744
A clinically interpretable deep learning pipeline for diabetic retinopathy classification using EfficientNet, advanced data augmentation and GradCAM.

BACKGROUND: Early and reliable grading of diabetic retinopathy is important for preventing avoidable vision loss. Although deep learning methods have ...

May 19 2026 42151890
CNS-Obsidian: A Neurosurgical Vision-Language Model Built From Scientific Publications.

BACKGROUND AND OBJECTIVES: General purpose vision-language models (VLMs) demonstrate impressive capabilities, but their opaque training on uncurated i...

May 19 2026 42153721
AI-guided integration of aging-related functional assessment to predict nonresponse to cardiac rehabilitation in heart failure.

BACKGROUND: Cardiac rehabilitation (CR) improves functional capacity and outcomes in patients with heart failure (HF). However, a clinically significa...

May 19 2026 42155949
Automated Safety Testing and Reporting Application for Conversational Safety Monitoring of Generative AI Tools for Mental Health: Development and Validation Study.

BACKGROUND: Artificial intelligence (AI)-based conversational tools are rapidly expanding within mental health care as a means of increasing access an...

May 19 2026 42155999
Randomised Controlled Multicentre Trial to Investigate the Effectiveness of a Mobile Artificial Intelligence Solution for Diabetes Adapted Care: The MELISSA Trial Protocol.

AIMS: Achieving optimal glycaemic control remains a burden for many people with diabetes on intensive insulin treatment. The MELISSA trial aims to cli...

May 19 2026 42156180
Personalized machine learning guided intervention for optimizing lifestyle behaviors in depression: a pilot study.

Personalized data-driven interventions for depression are much needed. Here, we leveraged N-of-1 machine learning (ML) to optimally target behavioral ...

May 19 2026 42151558
Revealing the divergences between LLM-simulated and human takeover decision-making in ADS-equipped HGV operations.

Global adoption of Level-3 (L3) autonomous driving systems (ADS) in commercial heavy goods vehicles (HGVs) remains limited, as concerns about reliabil...

May 18 2026 42150399
Artificial intelligence-assisted integrated care to promote colonoscopy uptakeĀ (AICC) in China: study protocol for a cluster randomized controlled trial.

BACKGROUND: Colorectal cancer (CRC) leads to heavy disease and economic burdens globally. Early screening such as colonoscopy has been demonstrated to...

May 18 2026 42152022
Application of artificial intelligence-assisted education for postoperative pulmonary rehabilitation: a hybrid model of AI and nurse-driven support.

OBJECTIVE: To explore the clinical value of AI-assisted pulmonary rehabilitation education in patients undergoing thoracoscopic surgery for lung cance...

May 18 2026 42152114
Multimodal Personalized Mobile Health Just-in-Time Adaptive Intervention for Occupational Stress Management: Pilot Study.

BACKGROUND: As digital health solutions gain traction, there is an urgent need for effective, person-centered stress management tools for employees. A...

May 18 2026 42150167
Research on strategies for enhancing the competency of safety directors in EPC projects empowered by AI.

With the widespread application of the engineering-procurement-construction (EPC) delivery model in large-scale infrastructure and complex industrial ...

May 18 2026 42149887
Predictors of the Efficacy of Focused Ultrasound for Moderate-to-Severe Persistent Allergic Rhinitis: A Retrospective Cohort Study.

BACKGROUND: Focused ultrasound (FUS) has achieved favorable results in the treatment of allergic rhinitis (AR). However, some patients still have poor...

May 17 2026 42144291
Interpersonal Predictors of Grief Among Caregivers of Persons With Dementia.

OBJECTIVE: Family caregivers of persons with dementia experience grief as the care recipients' dementia advances. Here, we explore how various interpe...

May 16 2026 42236383
Highly Efficient Broad-Spectrum Antibacterial Carbon Dots through Hierarchical Machine Learning Framework.

The global threat of antibiotic resistance necessitates intelligent design strategies for next-generation antibacterial nanomaterials. Herein, high-ef...

May 16 2026 42142065
Comparative study on the efficacy of large language models (LLMs) in health management for patients with urological and andrological diseases: a multidimensional quality evaluation and applicability analysis.

PURPOSE: This study aims to evaluate the efficacy of large language models (LLMs) in health management for urological and andrological conditions by c...

May 16 2026 42142252
Enhancing spectral analysis of ghee adulteration via a deep learning-based multimodal attention mechanism.

Expensive dairy products like ghee are at high risk of hazardous adulteration with cheaper fats, and traditional testing approaches such as FTIR devic...

May 16 2026 42143095
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