Clinical Trials

PregMedNet: Multifaceted maternal medication impacts on neonatal complications.

While medication use is common among pregnant women, medication safety remains insufficiently characterized because studies in pregnant women are challenging due to safety concerns. The recent digitization of healthcare databases and advances in computational methods have created new opportunities for large-scale, retrospective drug safety evaluations. Here, we present PregMedNet, a platform that ...

Development and validation of an AI-driven multimodal system for assessing aerobic gymnastics training using video analysis, motion capture, and physiological signals.

This research developed and validated a comprehensive multimodal assessment system integrating artificial intelligence for aerobic gymnastics training evaluation. A 12-week randomized comparative study recruited 600 participants (300 national-level athletes, mean age 22.4 ± 3.2 years; and 300 university students, mean age 20.8 ± 2.1 years) to establish normative performance databases and validate ...

Interpretable coal mine fault detection via orthogonal Kolmogorov-Arnold networks.

The continuous monitoring of safety within underground coal mines generates multivariate sensor data of high dimensionality, posing substantial challe...

Chatbot Use by Patients Seeking Urogynecologic Consultation: A Randomized Trial.

IMPORTANCE: Urogynecology patients increasingly investigate their problems using technology-based resources, yet the effect of artificial intelligence...

Nursing Leadership for Digital NICU Transformation: A Systematic Review of Strategies, Digital Health Integration, and Outcomes in High-Risk Neonates.

BACKGROUND: Digital health technologies are increasingly embedded in Neonatal Intensive Care Units (NICUs), yet the role of nurse-led governance in sh...

Effects of a generative AI-assisted ADPIE Framework on critical thinking, learning self-efficacy, and clinical reasoning in nursing education: a quasi-experimental study.

BACKGROUND: The nursing process is a systematic, patient-centered framework essential for clinical reasoning and decision-making in nursing education....

Epigenetic editing approaches maturity: AI-driven precision design, delivery innovation, and the road to clinical translation.

Epigenetic editing achieves durable gene silencing through targeted modification of chromatin and DNA methylation states without altering the genomic ...

Trustworthy AI for personalized glycemic control: a systematic review and critical appraisal of multimodal forecasting and safety-critical closed-loop control.

Tight glycemic control reduces acute complications (hypoglycemia, hyperglycemia) and long-term microvascular/macrovascular risks. The application of A...

Effectiveness of Humanized AI Avatars and Messenger Gender for Dental Postprocedure Instructions: Two Randomized Experiments.

BACKGROUND: Postcare instructions play a vital role in preventive health care. Traditionally, information on post-dental procedure care is provided th...

Multidisciplinary research priorities for artificial intelligence in mental health: a call to action.

The use of artificial intelligence (AI) is anticipated to transform mental health care. However, the rapid research growth in this field has outpaced ...

Infection prevention and control measures for Ebola and Marburg disease: a series of rapid reviews.

OBJECTIVES: An evidence synthesis informed the 2023 WHO infection prevention and control (IPC) guideline for Ebola disease (EBOD) and Marburg disease ...

Development and validation of a disease-syndrome integrated assessment model for AECOPD severity: protocol for a nationwide multicentre cross-sectional study.

INTRODUCTION: Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) accelerate disease progression and increase mortality. Accurate se...

AI-driven Chinese male facial skin phenotype profiling and its lifestyle correlation.

Concerns about facial skin health and aesthetics are increased among the male demographic, necessitating in-depth exploration of lifestyle factors on ...

Artificial Intelligence in Wilderness Search and Rescue: A Narrative Review.

Artificial intelligence (AI) is transforming wilderness Search and Rescue (SAR), where time constraints, austere conditions, and limited personnel hav...

Maxillary Anterior Horizontal Ridge Reconstruction using Computer-Guided Ridge Split and Expansion: A Randomized Clinical Trial with a 2-Year Follow-up.

OBJECTIVES: This randomized clinical study aimed to assess implant placement accuracy and radiographic outcomes of computer-guided versus freehand rid...

Mindfulness and artificial intelligence self-efficacy among university students: the mediating role of artificial intelligence literacy.

University students now use artificial intelligence (AI) tools in several academic activities, including information retrieval, writing support, and p...

An enhanced YOLOv10 framework for small-object safety helmet detection on construction sites.

Safety helmet compliance monitoring remains challenging because helmets often occupy only a few pixels in wide-area surveillance images. This study ta...

Multimodal imaging to analyze the biomechanical properties of kidney tumors, evaluating feasibility, inter-modality correspondence, and diagnostic value (UroCCR-115).

INTRODUCTION: Assessment of renal tissue and renal tumor stiffness may provide complementary information for tissue characterization; however, convent...

EXPRESS: It's not all rapid dilations: on contributions of constrictions, biphasic and minute-long vessel responses to brain functional hyperemia.

Though neurovascular coupling has long been studied, a comprehensive characterization of the extent, kinetics, and variability of individual microvess...

Evaluation of a sleep sound analysis smartphone app for home obstructive sleep apnea screening among community-dwelling Chinese adults with hypertension.

PURPOSE: This study aimed to evaluate the validity and feasibility of home obstructive sleep apnea screening using a sleep sound analysis smartphone a...