Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Safety-Oriented Evaluation of Large Language Models in Health Care: Guideline-Informed Systematic Review.

BACKGROUND: Large language models (LLMs) are rapidly emerging in health care, offering opportunities in decision support, education, and research, but raising critical concerns about safety, reliability, and ethics. Although several guidelines for trustworthy AI exist in business and technology, few systematic reviews have applied them to medical contexts. OBJECTIVE: This study aimed to conduct a ...

Aug 20 2026 42623243

Characterization of AF Recurrence and Substrate Health by Electrographic Flow (EGF) Consistency in EGF Mapping.

BACKGROUND: Electrographic flow (EGF) mapping is an FDA 510(k)-cleared method for visualizing atrial activation wavefronts in atrial fibrillation (AF). Its clinical efficacy in detecting AF sources was demonstrated in the FLOW-AF randomized controlled trial, and the underlying machine learning strategy used to develop and refine EGF source detection has been recently detailed. However, EGF mapping...

Aug 20 2026 42623431
Comparative Evaluation of Large Language Models in Answering Patient Questions Following Periodontal and Peri-Implant Examination: An Expert-Based Study.

INTRODUCTION: Large language models (LLMs) are increasingly utilized for medical and dental information retrieval, yet their ability to interpret auth...

Aug 20 2026 42624462
Responsible and innovative AI for mental health care: five priority themes.

Artificial intelligence (AI) has entered psychiatry at scale, yet its clinical impact remains constrained by a sizable gap between technical validatio...

Aug 20 2026 42624890
Global trends and emerging frontiers in robot-assisted vascular intervention: a comprehensive bibliometric analysis.

Robot-assisted vascular intervention may reduce occupational radiation exposure, improve procedural stability, and expand access to specialized endova...

Aug 19 2026 42616212
Influence of artificial intelligence on the performance of endosonographers in detection of solid pancreatic tumors: a tandem randomized video study.

BACKGROUND: This study aimed to evaluate the influence of a pre-commercial artificial intelligence (AI)-based software system on endosonographers' per...

Aug 19 2026 42617651
The Reliability of Human Evaluation of Large Language Models in Health Care Settings: Scoping Review.

BACKGROUND: Integration of large language models (LLMs) into health care has accelerated rapidly, yet reliability concerns pose potential risks to pat...

Aug 19 2026 42618044
Prospective evaluation of a large language model clinical decision support system in the emergency department.

Prospective evidence for artificial intelligence (AI)-based clinical decision support in emergency departments remains limited. Here we conducted a DE...

Aug 19 2026 42618632
Large-scale AI-guided liver malignancy diagnosis: multicenter study and a single-arm trial.

Liver malignancies are frequently evaluated on contrast-enhanced computed tomography (CE-CT), but missed or delayed diagnoses remain a clinically impo...

Aug 19 2026 42618635
User evaluation of AI- and human-generated responses in digital health communication: a paired survey study.

BACKGROUND: Digital health communication is gaining importance as health care systems face increasing demand and structural constraints. Generative ar...

Aug 19 2026 42618915
Mitochondria-Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential.

Aging is a significant risk factor of neurodegenerative disorders (NDs) such as Huntington's, Alzheimer's, Parkinson's, amyotrophic lateral sclerosis ...

Aug 19 2026 42619255
Percutaneous thermal ablation for renal cell carcinoma: a comprehensive review of current evidence and future directions.

Thermal ablation (TA), including microwave ablation, radiofrequency ablation, and cryoablation, is increasingly used as a surgical alternative for T1a...

Aug 18 2026 42613495
Managing risk and reward: Exploring immigrant platform workers' occupational safety and wellbeing through a sociotechnical lens.

BackgroundThe rise of digital platforms and algorithmically-managed labour is reshaping traditional understandings of job quality, safety, and wellbei...

Aug 18 2026 42613590
Artificial intelligence-enhanced management system for secondary prevention of coronary heart disease: a randomized clinical trial.

BACKGROUND: Secondary prevention of coronary heart disease (CHD) remains suboptimal due to fragmented care and therapeutic inertia. While digital heal...

Aug 18 2026 42613609
Predicting perceived learning effectiveness from generative artificial intelligence in higher education: a hierarchical regression analysis of psychological, behavioral, and cognitive factors.

This study examines predictors of students' perceived learning effectiveness from generative artificial intelligence (GenAI) in higher education by in...

Aug 18 2026 42611088
ChatGPT-4o as a decision-support tool in a urological tumour board: a prospective evaluation.

PURPOSE: To evaluate ChatGPT-4o in a real-world urological multidisciplinary tumour board (MTB), with concordance for the final clinical recommendatio...

Aug 18 2026 42611131
Barriers and Facilitators to AI Implementation in Intensive Care Units in China: Qualitative Study Among Nurse Managers.

BACKGROUND: AI has shown significant potential in intensive care unit (ICU) nursing practice, enhancing efficiency, decision-making, and patient safet...

Aug 18 2026 42612044
Gerontechnology Acceptance in Thai Older Adult Care Facilities-Sensor Network and Machine Learning Adoption: Mixed Methods Study.

BACKGROUND: Thailand is undergoing a rapid demographic transition, with an estimated 28% of the population expected to be aged 60 years or older by 20...

Aug 18 2026 42612072
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