Latest AI and machine learning research in clinical trials for healthcare professionals.
The integration of artificial intelligence, protein engineering, and sustainable nanomedicine is driving a paradigm shift in theranostics by enabling highly precise disease diagnosis and targeted therapy. AI-driven methodologies, including machine learning and deep learning, facilitate the rapid analysis of complex biological and chemical datasets, accelerating protein structure prediction, molecu...
Clinical trial enrollment in oncology remains limited by increasingly complex eligibility criteria, biomarker stratification, and fragmented clinical data, contributing to prolonged recruitment timelines and low participation rates. This review examines contemporary pre-screening and screening approaches, spanning manual workflows, health-system-embedded digital tools, and emerging artificial inte...
PURPOSE: The Novara Cohort Study (NCS) was established to investigate the biological, psychological and social factors that influence ageing in the ge...
INTRODUCTION: Patient safety event reporting systems are widely used, yet organisations face challenges analysing the high volume of incident reports....
Soil-transmitted helminth (STH) infections are exceedingly common, estimated to afflict 1.5 billion individuals worldwide, or 24% of the total populat...
BACKGROUND: The glymphatic system plays a critical role in brain waste clearance and health. Diffusion tensor imaging along the perivascular space (DT...
BACKGROUND: Acute respiratory distress syndrome (ARDS) is a heterogeneous syndrome with high mortality. Subphenotyping may identify more homogeneous g...
Body-centered cubic (bcc) alloys can achieve gigapascal-level yield strengths but typically are limited in tensile ductility (<20%), contrasting sharp...
The evolution of root nodule symbiosis (RNS), a key innovation for plant nitrogen acquisition, has long been studied but lacks a mechanistic, gene-lev...
ETHNOPHARMACOLOGICAL RELEVANCE: In Traditional Chinese Medicine (TCM), Dendrobium species have long been utilized to alleviate various inflammatory sy...
The global demand for cosmetic procedures is accelerating, with over 1.6 million aesthetic surgical procedures performed in the US in 2023. Concurrent...
Rectal cancer management has increasingly shifted toward organ-preserving strategies that aim to maintain oncologic control while preserving bowel, ur...
BACKGROUND: Rib fractures are present in 10%-15% of thoracic trauma cases but are often missed on chest radiographs, delaying diagnosis and treatment....
BACKGROUND: Bleeding complications are a major contributor to adverse drug events among older inpatients, particularly in those treated with antithrom...
BACKGROUND: Suicide rates have increased over the last couple of decades globally, particularly in the United States and among populations with lower ...
Drug-drug interaction (DDI) poses a major challenge in clinical pharmacology, often compromising therapeutic efficacy or causing serious adverse event...
BACKGROUND: The increasing integration of artificial intelligence (AI) into healthcare has generated interest in its potential role within nursing pra...
OBJECTIVE: Large Language Models (LLMs) show strong potential in biomedical informatics but frequently generate hallucinated or factually incorrect re...
Immunotherapy, a therapeutic strategy aimed at modulating the host immune system, has undergone rapid evolution over recent decades, particularly in o...
BACKGROUND: Intravascular lithotripsy (IVL) emerged for the treatment of coronary artery calcification with encouraging safety and effectiveness rates...