Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Advanced Prompting Techniques Informed by Clinical Expertise Improve the Accuracy of LLM Data Extraction but Increase Non-Determinism.

Prompt engineering techniques which aid in the use of generative artificial intelligence to address classification tasks have expanded considerably in the last 2 years. The success of such methods varies depending on context, and their efficacy in extracting structured data from unstructured medical text is not well understood. In this paper, five large language prompting strategies were evaluated...

Mar 11 2026 41814072

Analysis of the effects of individual characteristics, safety training and awareness of dockers on occupational accidents using accident causality models.

Objectives. This research aims to provide information on factors that may affect the accident susceptibility of workers by using various individual characteristics of workers as variables with machine learning algorithms, and the effects of occupational health and safety (OHS) training and workers' safety awareness within this interaction. Methods. Research data were obtained through surveys admin...

Mar 11 2026 41812076
Mortality score in chronic coronary syndrome: prediction model from the ISCHEMIA trial.

AIMS: Accurate stratification of mortality risk is essential for management of chronic coronary syndromes (CCS), but existing models focus primarily o...

Mar 11 2026 41812133
AI-Enhanced Conversational Agents for Personalized Asthma Support in People With Asthma: Factors for Engagement, Value, and Efficacy in a Cross-Sectional Survey Study.

BACKGROUND: Asthma-related deaths in the United Kingdom are the highest in Europe, and only 30% of patients access basic care. There is a need for alt...

Mar 11 2026 41812152
Diagnostic, predictive, and therapeutic approaches for impacted canines: a systematic review and meta-analysis.

OBJECTIVE: Maxillary canine impaction affects approximately 1-3% of the population and presents diagnostic, prognostic, and therapeutic challenges. Th...

Mar 10 2026 41807950
A deep reinforcement learning algorithm for optimizing safety and efficiency of traffic signals using traffic conflict technique and artificial intelligence-based video analytics.

The advancements in computer vision have opened doors to estimate crash risks in real-time and revisit traffic signal systems to optimize safety and e...

Mar 10 2026 41812491
Artificial Intelligence Models for Predicting Triage in Emergency Departments: Seven-Month Retrospective Comparative Study of Natural Language Processing, Large Language Model, and Joint Embedding Predictive Architectures.

BACKGROUND: Triage errors in emergency departments (EDs), including undertriage and overtriage, pose significant risks to patient safety and resource ...

Mar 10 2026 41805589
Florida golf cart crashes (2011-2021): a statewide analysis of crash patterns and predictors.

OBJECTIVE: Golf carts are increasingly sharing public roads with other vehicles, creating new safety challenges due to their design limitations and ga...

Mar 10 2026 41805591
Clinical implementation of AI for vertebral fracture detection in CT aligned with fracture liaison services: high prevalence of undiagnosed vertebral fractures.

UNLABELLED: We assessed feasibility and effectiveness of AI-based VF screening in CT, integrated with a local FLS. The system identified VFs in 14% of...

Mar 10 2026 41805842
AGPAT3 reshapes tumor cell vulnerability to IFNγ-mediated ferroptosis and enhances immunotherapy efficacy through lipid remodeling.

BACKGROUND: Ferroptosis plays a critical role in immune regulation and tumor microenvironment remodeling. However, its therapeutic potential in enhanc...

Mar 10 2026 41807033
Evaluating Large Language Models-Generated Health Education Materials for Discharged Patients with Diabetes: A Comparative Analysis.

BACKGROUND: Diabetes is a chronic condition requiring long-term management, and continuous health education is vital for improving disease awareness a...

Mar 10 2026 41807129
[Discovery of multi-omics-based biomarkers for immune-related adverse events: precision management with 3D-SPACE].

This article provides a systematic review of the advances in the precise diagnosis and management of immune-related adverse events (irAEs) induced by ...

Mar 10 2026 41796001
Application of artificial intelligence in schizophrenia rehabilitation management: a systematic scoping review.

Artificial intelligence (AI) is increasingly used in mental health, yet its rehabilitation-oriented applications in schizophrenia have not been system...

Mar 9 2026 41803101
Harnessing the Power of artificial intelligence for clinical trials in cancer.

INTRODUCTION: Cancer research has become increasingly data-intensive, with digital pathology, imaging, and genomic sequencing generating vast, heterog...

Mar 9 2026 41797434
Deep Brain Stimulation Induces Antidepressant Effects by Restoring High-Fidelity Communication in the BNST-NAc Circuit.

Deep brain stimulation (DBS) for treatment-resistant depression (TRD) is challenged by significant individual variability in efficacy and unclear neur...

Mar 9 2026 41801046
Effect of a Computer-Aided Device for Detecting Gastric Neoplasms: A Multicenter, Randomized Controlled Trial.

BACKGROUND & AIMS: Evidence about the effect of artificial intelligence (AI) on upper endoscopy in multicenter, randomized controlled trials is lackin...

Mar 9 2026 41801173
Effectiveness of meditation in the management of epilepsy: An updated mini systematic review of recent findings.

BACKGROUND: Epilepsy is a chronic neurological disorder characterized by altered cortical excitability. The disorder is often associated with psycholo...

Mar 8 2026 41806957
Promoting clinical trials in pediatric IgA nephropathy through extrapolation: an artificial intelligence-enhanced literature review of the disease in pediatrics sponsored by the Kidney Health Initiative.

BACKGROUND: There is an urgent need to evaluate the efficacy of novel therapeutics that have been approved for use in adults with IgA nephropathy (IgA...

Mar 8 2026 41795009
Tumor burden in metastatic colorectal cancer quantified using deep learning models: Prognostic value and maintenance treatment benefit in the CAIRO3 trial.

INTRODUCTION: Total tumor number (TTN) and total tumor volume (TTV) reflect tumor burden and have been linked to outcomes in metastatic colorectal can...

Mar 7 2026 41819026
Pharmacokinetic modeling to optimize development and therapeutic potential of mAb-based therapies.

Monoclonal antibody (mAb)-based therapies have revolutionized modern medicine, offering highly specific and effective treatments for a wide range of d...

Mar 6 2026 41796750
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