Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Factors Influencing Nursing Internship Students' Readiness to Use AI: Cross-Sectional Study Using Neural Network Analysis.

BACKGROUND: Enhancing nursing students' awareness, attitudes, beliefs, and preparedness toward AI may help improve their health care knowledge and practice. OBJECTIVE: This study aimed to assess nursing students' attitudes, perceptions, self-efficacy, barriers, and anxiety, which influence their readiness to adopt AI in nursing practice. METHODS: This study used a cross-sectional, correlational de...

Aug 18 2026 42612089

NeuroSift for Task-Aware Quality Assurance of Multimedia Data in Remote Parkinson Disease Assessment: Machine Learning Model Development and Validation Study.

BACKGROUND: Automated multimedia analysis of remotely recorded tasks offers a scalable approach to screening and remote monitoring of movement disorders such as Parkinson disease (PD). However, unsupervised recordings often suffer from quality issues that compromise model reliability. General multimedia quality checks may not detect task-specific failures, such as poor hand visibility during finge...

Aug 18 2026 42612206
Multimodal Artificial Intelligence System for Risk-Adapted Cancer Survivorship Surveillance: A Multicenter Target Trial Emulation.

BACKGROUND: The growing population of cancer survivors faces immense monitoring burdens due to rigid follow-up guidelines, such as the intensive surve...

Aug 18 2026 42612835
Protocol for a pilot effectiveness and feasibility randomized controlled trial of an advanced telerehabilitation system for people with multiple sclerosis (PLATINUMS project).

BACKGROUND: Multiple Sclerosis (MS) causes many different symptoms, with some of the most dominant being impaired balance and walking performance. Exe...

Aug 18 2026 42611888
Evaluation of Computer-aided Detection for Identifying Missed Gastric Cancer After Endoscopic Submucosal Dissection.

OBJECTIVES: Computer-aided detection (CADe) using deep learning is promising for reducing missed gastric cancers (MGCs) and supporting physicians in d...

Aug 17 2026 42609944
Deep-Learning Based Contrast Boosting: A Multi-Center Multi-Reader Study on Clinical Performance With Standard Contrast Enhanced Brain MRI.

BACKGROUND: Gadolinium-based contrast agents are used in brain MRI to improve the visualization of disorders and improve the delineation of lesions. H...

Aug 17 2026 42608386
Physics-informed deep learning for robust trajectory prediction in automated driving.

Planning a safe, comfortable, and energy-efficient ego-vehicle trajectory is fundamental for automated driving. Efficiency reduces emissions, while sa...

Aug 17 2026 42608438
CKLF1 Serves as a Pivotal Mediator of Blood-Brain Barrier Disruption and Neuroinflammation via PI3K/AKT/mTOR Signaling in Ischemic Stroke.

Ischemic stroke (IS) is accompanied by blood-brain barrier (BBB) disruption and neuroinflammatory activation, but the upstream regulatory mechanisms r...

Aug 17 2026 42608489
Radiomics Integrated with Deep Learning Based on Contrast-Enhanced MRI for Predicting Short-Term Efficacy of Drug-Eluting Beads Transarterial Chemoembolization in Hepatocellular Carcinoma from Multicenter Retrospective Study.

We aimed to develop and validate a predictive model combining radiomics, deep learning, and clinical features for the preoperative prediction of the s...

Aug 17 2026 42608639
Integrating Cardiovascular Screening in Lung Cancer Screening.

Cardiovascular risk assessment is a natural extension of lung cancer screening (LCS) because individuals eligible for low-dose computed tomography oft...

Aug 17 2026 42608820
Radiotherapy and immunotherapy in cancer treatment: mechanisms of clinical synergy.

Synergizing radiotherapy (RT) with immune checkpoint inhibitors has emerged as a promising strategy for solid tumors. RT acts as a potent immunomodula...

Aug 17 2026 42606129
Comparison of a Computable Pediatric Sepsis Phenotype Tool in Argentinian and U.S. Cohorts.

OBJECTIVE: Sepsis is a leading cause of mortality in low- and middle-income countries. This study identifies computable pediatric sepsis phenotypes (P...

Aug 17 2026 42606293
Correction to "Contributing factors to beneficence and nonmaleficence in police-led jail diversion programs" by Petreca et al. (2025).

UNLABELLED: Reports an error in "Contributing factors to beneficence and nonmaleficence in police-led jail diversion programs" by Victor G. Petreca, M...

Aug 17 2026 42606829
A Randomized Controlled Trial Evaluating Digital Health Intervention on Phosphate Control in Patients on Dialysis.

BACKGROUND: Hyperphosphataemia is a common metabolic complication of CKD and is associated with poor health outcomes. Dietary intervention is a key st...

Aug 17 2026 42606901
AI-generated patient instructions as safety-critical communication: a provisional evidence-informed framework for clinical deployment.

Generative artificial intelligence (AI) can convert clinical information into patient-facing instructions, including discharge summaries, medication e...

Aug 17 2026 42607431
Direct Comparison Between Loss-to-Follow-Up and Statistical Fragility Is Methodologically Inappropriate, and Fragility Reflects the P Value, Not Trial Robustness: A Simulation Analysis of 300,000 Randomized Controlled Trials.

PURPOSE: To assess the relation between the fragility index (FI) and reverse fragility index (RFI) with the minimum number of patients needed to rever...

Aug 16 2026 42605132
Editorial Commentary: Machine Learning and 300,000 Simulations Confirm That Fragility Reflects the P Value, Not Trial Robustness: Taking Apart a Calculator to Reveal That 2 + 2 Equals 4.

The fragility index continues to be promoted as a measure of trial robustness despite evidence that it is little more than statistical significance in...

Aug 16 2026 42605153
Perceived coping and healing among Chinese emerging-adult users: The shaping role of AI emotional companion agents.

AI emotional companion agents are increasingly used for everyday emotional support, yet evidence remains limited regarding how observable service cues...

Aug 14 2026 42600455
Health Care Professionals' Perspectives on Conversational Mental Health Chatbots: Protocol for a Systematic Review.

BACKGROUND: Mental health disorders (MHDs) represent a growing global challenge and pose a significant risk to public health. Alongside developments i...

Aug 14 2026 42600062
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