Clinical Trials

Alleviating Nurse Burnout With an Artificial Intelligence-Selected Mobile Cognitive Behavioral Therapy-Based Intervention: Mixed Methods Randomized Controlled Trial.

BACKGROUND: Nurse burnout is a pervasive global problem. Cognitive behavioral therapy (CBT) has been shown to reduce burnout; however, most digital CBT programs use standardized approaches that overlook individual differences in burnout profiles. With advances in artificial intelligence (AI), algorithm-based recommendation systems now enable personalized intervention delivery by matching specific ...

Real-Time Smartphone Monitoring Assessments as a Cognitive Biomarker of Alzheimer Disease: Protocol for a Development Study.

BACKGROUND: The diagnosis and monitoring of Alzheimer disease (AD) currently rely on clinician-administered, in-person, and cross-sectional pen-and-paper cognitive assessments. While clinically validated, these measures are time-intensive, infrequently administered, and limited in their ability to detect early, subtle, or short-term cognitive changes. Thus, more frequent, ecologically valid assess...

Evaluation and Comparison of Latent Health Risk Prediction Models for Clinical Triage: Protocol for a Mixed Methods Study.

BACKGROUND: Clinical triage requires integrating multiple information sources to identify patients at risk of deterioration. Tools capturing global he...

A randomized controlled trial evaluating the use of an intelligent, fully automated 2D imaging system to detect lame cows and control lameness.

A fully automated 2-dimensional imaging system that uses machine learning to produce real-time mobility scores has been developed and previously exter...

Can Consumers Rely on AI Chatbots for Food Safety Advice? A Comparative Analysis of Chatbot Responses and Food Safety Specialists' Guidance.

The growing integration of artificial intelligence tools, particularly conversational agents, is transforming how consumers access information, includ...

Artificial Intelligence-Mediated Discharge Document for Accessible Health Care (AIM-HEALTH): Protocol for a Prospective, Observational, Noninterventional Study.

BACKGROUND: Hospital discharge reports (HDRs) support continuity of care; yet, their specialized terminology may hinder patient understanding and post...

Comparative Effectiveness of AI-Assisted Telerehabilitation, Telerehabilitation, In-Person Care, and Usual Care for Chronic Nonspecific Low Back Pain: Bayesian Network Meta-Analysis.

BACKGROUND: Guided exercise is central to rehabilitation for chronic nonspecific low back pain. Telerehabilitation enables remote delivery of guided e...

Artificial intelligence integration and patient safety culture: a cross-sectional study of healthcare professionals in Riyadh, Saudi Arabia.

BACKGROUND: This cross-sectional study investigates healthcare practitioners' perceptions of the implementation of artificial intelligence (AI) to enh...

Complex-valued amplitude-phase interference modeling for adversarially robust classification.

Deep neural networks have achieved remarkable progress in computer vision and related tasks. However, their high sensitivity to even subtle adversaria...

Technical and clinical feasibility of single-use gastroscopy with real-time AI-based quality monitoring and single-use colonoscopy: a prospective two-center study.

BACKGROUND: Single-use gastrointestinal endoscopes eliminate the need for post-procedure reprocessing and have become an area of interest in endoscopi...

Factors influencing the trustworthiness of non-randomized studies of interventions: a survey of international experts.

BACKGROUND: Perceived trustworthiness of research may be influenced by factors beyond the risk of bias, including study-related characteristics, resea...

Who benefits most? A randomized controlled trial for Parent-implemented social communication intervention for chinese-speaking autistic preschoolers.

BACKGROUND: Parent-implemented interventions (PIIs) are well established for improving developmental outcomes in autistic children. As evidence has ac...

Leveraging multimodal cancer immunotherapy to amplify the efficacy of oncolytic viruses.

Oncolytic viruses (OVs) represent a versatile platform for cancer immunotherapy, capable of selectively infecting and lysing tumor cells while trigger...

[Research progress on artificial intelligence-driven digital removable partial denture clinical diagnosis and treatment].

Clinical practice of digital removable partial denture (RPD) has undergone two profound transformations, shifting from partial digital substitution to...

Voice Cloning Using AI vs Traditional Audio Recording for Prerecorded Courses in Medical Pedagogy: Randomized Controlled Trial.

BACKGROUND: Prerecorded courses are increasingly used in medical education, and audio quality is known to influence learners' comprehension and engage...

A Validated, Modifiable Proteomic Score from the EXSCEL Trial Predicts Cardiovascular Events in Diabetes.

Adults with type 2 diabetes mellitus (T2DM) are at increased risk for stroke, myocardial infarction, and cardiovascular death, yet individual risk is ...

Ambient AI Scribes and Emergency Department Documentation Burden: Retrospective Cohort Study.

BACKGROUND: Clinician burnout has reached crisis levels in emergency medicine, with clinical documentation burden identified as a central contributing...

Modeling road-segment-level speeding risk of new energy vehicle taxis using a multistage framework with spatial spillover, endogeneity, and nonlinear effects.

Speeding poses a critical risk to urban traffic safety, especially for new energy vehicle taxis, whose capacity of high torque and rapid acceleration ...

Pre-service foreign language teachers' acceptance of ChatGPT in microteaching lesson planning: A sequential mixed-methods study.

This study provides context-specific exploratory evidence on how pre-service foreign language teachers perceive ChatGPT during microteaching lesson pr...

Theoretical and Psychological Mechanisms of Perceptual-Motor Learning in AI Bots-Assisted Art Education.

The integration of Artificial Intelligence (AI) into art education presents a complex shift in perceptual-motor learning, yet the psychological mechan...