Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Beyond black boxes: using explainable causal artificial intelligence to separate signal from noise in pharmacovigilance.

Artificial intelligence (AI), particularly machine learning (ML), is increasingly influencing pharmacovigilance (PV) by improving case triage and signal detection. Several studies have reported encouraging performance, with high F1 scores and alignment with expert assessments, suggesting that AI tools can help prioritize reports and identify potential safety issues faster than manual review. Howev...

Sep 1 2025 40889016

Central venous catheters tip positioning: Insights from a retrospective analysis.

BACKGROUND: Tunneled central venous catheters (tCVCs) are essential in hemodialysis when arteriovenous access is not feasible. Their correct positioning is crucial to ensure efficient dialysis and prevent complications such as stenosis and thrombosis. METHODS: This retrospective, non-randomized study reviewed all tCVC placements performed from January 2017 to December 2024 at the Nephrology Depart...

Aug 29 2025 40878638
Spectroscopic characterization of three fungicides using terahertz spectroscopy and DFT theory, combined with convolutional neural networks for quantitative analysis of tebuconazole.

Fungicides are essential agrochemicals for the prevention and control of plant diseases. Counterfeit products, often lacking enough active ingredients...

Aug 27 2025 40902373
Screening for Barrett Esophagus and Esophageal Adenocarcinoma: Approaches and Outcomes.

Barrett esophagus (BE) is the only known histological precursor to esophageal adenocarcinoma (EAC). The incidence of EAC has risen significantly over ...

Aug 25 2025 40874980
Navigating Medical Device Safety: Current Status, Challenges, and Future Regulatory Directions.

Medical devices are indispensable in modern healthcare. They enable the prevention, diagnosis, and treatment of diseases while enhancing patient outco...

Aug 20 2025 40833550
Are Artificial Intelligence Models Reliable for Clinical Application in Pediatric Fracture Detection on Radiographs? A Systematic Review and Meta-analysis.

BACKGROUND: Artificial intelligence (AI) applications for pediatric fracture diagnosis using radiographs have demonstrated growing potential in clinic...

Aug 20 2025 40839831
Real-time Use of Computer-aided Diagnosis in the Optical Diagnosis of Gastric Neoplasia: A Multicenter Randomized Controlled Trial.

BACKGROUND & AIMS: The multicenter, randomized, control trial was conducted to evaluate whether computer-aided diagnosis (CADx) improves the optical d...

Aug 12 2025 40812472
Efficacy of artificial intelligence for adenoma detection in water exchange colonoscopy: a two-center randomized controlled trial.

Water exchange and artificial intelligence-based computer-aided detection (CADe) separately improve the adenoma detection rate (ADR) and number of ade...

Aug 11 2025 40789324
Function of chemokines in embryo implantation.

Embryo implantation centrally involves the maternal immune system's specific acceptance of the semi-allogeneic embryo. Despite advances in assisted re...

Aug 5 2025 40769846
AI-assisted script concordance tests: Enhancing feasibility with customized ChatGPT.

WHAT WAS THE EDUCATIONAL CHALLENGE?: The Script Concordance Test (SCT) assesses clinical reasoning by evaluating responses to uncertain scenarios agai...

Jul 24 2025 40705532
Pre-interventional transesophageal echocardiography as a reliable predictor of residual shunt following patent foramen ovale closure.

BACKGROUND: Closure of a patent foramen ovale (PFO) is an effective strategy in the prevention of recurrent stroke after cryptogenic stroke. Residual ...

Jul 24 2025 40705044
Perspectives on data analytics for gaining a competitive advantage in football: computational approaches to tactics.

The role of data-driven analyses is becoming more prominent in football. These have the potential to impact decision-making processes for team perform...

Jul 21 2025 40689477
Comparison of the effects of robot-assisted gait training using FES versus virtual reality for stroke patients. A randomized clinical trial.

BACKGROUND: Robot-assisted gait training is becoming an effective alternative to therapist-assisted gait training in stroke rehabilitation. This metho...

Jul 13 2025 40653600
AI-driven robotic surgery in oncology: advancing precision, personalization, and patient outcomes.

Artificial intelligence (AI) integrated with robotic systems is transforming oncologic surgery by significantly improving precision, safety, and perso...

Jul 12 2025 40652109
RadientFusion-XR: A Hybrid LBP-HOG Model for COVID-19 Detection Using Machine Learning.

The rapid and accurate detection of COVID-19 (coronavirus disease 2019) from normal and pneumonia chest x-ray images is essential for timely diagnosis...

Jul 11 2025 40641249
Feasibility study of using GPT for history-taking training in medical education: a randomized clinical trial.

BACKGROUNDS: Traditional methods of teaching history-taking in medical education are limited by scalability and resource intensity. This study aims to...

Jul 10 2025 40640776
StackPIP: An Effective Computational Framework for Accurate and Balanced Identification of Proinflammatory Peptides.

Proinflammatory peptides (PIPs) play a crucial role in immune response modulation by orchestrating cytokine release and leukocyte recruitment. Accurat...

Jul 10 2025 40641221
Humanizing AI training for health professions educators.

WHAT WAS THE EDUCATIONAL CHALLENGE?: Health professions educators grapple with profound emotional burdens-technology-related distress, gnawing self-do...

Jul 9 2025 40632734
A Comprehensive Review of Terahertz Time-Domain Spectroscopy for Agri-Food Safety Detection: Enhanced Sensing Performance Through Multidisciplinary Technology Integration.

The development of efficient and accurate methods for detecting contamination in agri-foods is critical for ensuring food safety. Terahertz time-domai...

Jul 9 2025 40632576
CRISPR/Cas-Based Biosensing Strategies for Non-Nucleic Acid Contaminants in Food Safety: Status, Challenges, and Perspectives.

Non-nucleic acid targets (non-NATs), such as heavy metals, toxins, and pesticide residues, pose critical threats to food safety. Although CRISPR/Cas s...

Jul 9 2025 40632760
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