Clinical Trials

Re: Health Related Quality of Life of Patients with Bladder Cancer in the RAZOR Trial: A Multi-institutional Randomized Trial Comparing Robot Versus Open Radical Cystectomy.

Effect of Machine Learning on Dispatcher Recognition of Out-of-Hospital Cardiac Arrest During Calls to Emergency Medical Services: A Randomized Clinical Trial.

IMPORTANCE: Emergency medical dispatchers fail to identify approximately 25% of cases of out-of-hosp...

The diagnosis of tuberculous meningitis in adults and adolescents: protocol for a systematic review and individual patient data meta-analysis to inform a multivariable prediction model.

Tuberculous meningitis (TBM) is the most lethal and disabling form of tuberculosis. Delayed diagnos...

Robotic Assessment of Upper Limb Function in a Nonhuman Primate Model of Chronic Stroke.

Stroke is a leading cause of death and disability worldwide and survivors are frequently left with l...

Caffeine mouth rinse enhances performance, fatigue tolerance and reduces muscle activity during moderate-intensity cycling.

We investigated the effects of caffeine mouth rinse on endurance performance, muscle recruitment (i....

Safety critical event prediction through unified analysis of driver and vehicle volatilities: Application of deep learning methods.

Transportation safety is highly correlated with driving behavior, especially human error playing a k...

Effect of combined home-based, overground robotic-assisted gait training and usual physiotherapy on clinical functional outcomes in people with chronic stroke: A randomized controlled trial.

OBJECTIVES: To assess the effect of a home-based over-ground robotic-assisted gait training program ...

Applications of artificial intelligence in drug development using real-world data.

The US Food and Drug Administration (FDA) has been actively promoting the use of real-world data (RW...

Ontological representation, classification and data-driven computing of phenotypes.

BACKGROUND: The successful determination and analysis of phenotypes plays a key role in the diagnost...

Deep learning-based real-time volumetric imaging for lung stereotactic body radiation therapy: a proof of concept study.

Due to the inter- and intra- variation of respiratory motion, it is highly desired to provide real-t...

Artificial intelligence in drug discovery: what is realistic, what are illusions? Part 1: Ways to make an impact, and why we are not there yet.

Although artificial intelligence (AI) has had a profound impact on areas such as image recognition, ...

One of the first validations of an artificial intelligence algorithm for clinical use: The impact on intraoperative hypotension prediction and clinical decision-making.

This review describes the steps and conclusions from the development and validation of an artificial...

Impact of Supplementation with Omega-3 in the Prevention of Contrast-Induced Nephropathy Following Elective Percutaneous Coronary Intervention in Patients with Chronic Kidney Disease: A Randomized Placebo-Controlled Trial.

BACKGROUND: Anti-oxidants were investigated in several studies as a preventive strategy for preventi...

Mid-term prediction of at-fault crash driver frequency using fusion deep learning with city-level traffic violation data.

Traffic violations and improper driving are behaviors that primarily contribute to traffic crashes. ...

Safety Evaluation and Experimental Study of a New Bionic Muscle Cable-Driven Lower Limb Rehabilitation Robot.

Safety is a significant evaluation index of rehabilitation medical devices and a significant precond...

Efficacy and safety of combined endoscopic cyanoacrylate injection and balloon-occluded retrograde transvenous occlusion (BRTOcc) of gastrorenal shunts in patients with bleeding gastric fundal varices.

BACKGROUND: Endoscopic cyanoacrylate (glue) injection of fundal varices may result in life-threateni...

Generalized Radiographic View Identification with Deep Learning.

To explore the feasibility of an automatic machine-learning algorithm-based quality control system f...

A Comparison of Artificial Intelligence and Human Doctors for the Purpose of Triage and Diagnosis.

AI virtual assistants have significant potential to alleviate the pressure on overly burdened health...

Using Artificial Intelligence to Predict Change in Depression and Anxiety Symptoms in a Digital Intervention: Evidence from a Transdiagnostic Randomized Controlled Trial.

While digital psychiatric interventions reduce treatment barriers, not all persons benefit from this...

Comparison of intravenous sodium bicarbonate and sodium chloride combination versus intravenous sodium chloride hydration alone in reducing amphotericin B nephrotoxicity: a randomized clinical trial.

BACKGROUND AND PURPOSE: The most important adverse reaction of amphotericin B (AmB) is nephrotoxicit...

Efficacy predictors of omalizumab in Chinese patients with moderate-to-severe allergic asthma: Findings from a analysis of a randomised phase III study.

BACKGROUND: Omalizumab has demonstrated efficacy as an add-on therapy in Chinese patients with moder...