Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Definition and Validation of Prognostic Phenotypes in Moderate Aortic Stenosis.

BACKGROUND: Adverse outcomes from moderate aortic stenosis (AS) may be caused by progression to severe AS or by the effects of comorbidities. In the absence of randomized trial evidence favoring aortic valve replacement (AVR) in patients with moderate AS, phenotyping patients according to risk may assist decision making.

Aug 14 2024 39152961

Randomized algorithms for large-scale dictionary learning.

Dictionary learning is an important sparse representation algorithm which has been widely used in machine learning and artificial intelligence. However, for massive data in the big data era, classical dictionary learning algorithms are computationally expensive and even can be infeasible. To overcome this difficulty, we propose new dictionary learning methods based on randomized algorithms. The co...

Aug 10 2024 39168071
Prognostic enrichment for early-stage Huntington's disease: An explainable machine learning approach for clinical trial.

BACKGROUND: In Huntington's disease clinical trials, recruitment and stratification approaches primarily rely on genetic load, cognitive and motor ass...

Aug 10 2024 39142216
Deep learning versus manual morphology-based embryo selection in IVF: a randomized, double-blind noninferiority trial.

To assess the value of deep learning in selecting the optimal embryo for in vitro fertilization, a multicenter, randomized, double-blind, noninferiori...

Aug 9 2024 39122964
Unraveling the impact of therapeutic drug monitoring via machine learning for patients with sepsis.

Clinical studies investigating the benefits of beta-lactam therapeutic drug monitoring (TDM) among critically ill patients are hindered by small patie...

Aug 9 2024 39127039
Recent progress in artificial intelligence and machine learning for novel diabetes mellitus medications development.

Diabetes mellitus, stemming from either insulin resistance or inadequate insulin secretion, represents a complex ailment that results in prolonged hyp...

Aug 8 2024 39083361
Graph Embedded Ensemble Deep Randomized Network for Diagnosis of Alzheimer's Disease.

Randomized shallow/deep neural networks with closed form solution avoid the shortcomings that exist in the back propagation (BP) based trained neural ...

Aug 8 2024 36112566
AI-based automation of enrollment criteria and endpoint assessment in clinical trials in liver diseases.

Clinical trials in metabolic dysfunction-associated steatohepatitis (MASH, formerly known as nonalcoholic steatohepatitis) require histologic scoring ...

Aug 7 2024 39112795
Predicting Metformin Efficacy in Improving Insulin Sensitivity Among Women With Polycystic Ovary Syndrome and Insulin Resistance: A Machine Learning Study.

OBJECTIVE: Metformin is clinically effective in treating polycystic ovary syndrome (PCOS) with insulin resistance (IR), while its efficacy varies amon...

Aug 5 2024 39111591
Robotic-Enhanced Prosthetic Liners for Vibration Therapy: Reducing Phantom Limb Pain in Transfemoral Amputees.

Phantom limb pain, a common challenge for amputees, lacks effective treatment options. Vibration therapy is a promising non-pharmacologic intervention...

Aug 3 2024 39124074
CBAM VGG16: An efficient driver distraction classification using CBAM embedded VGG16 architecture.

Driver monitoring systems (DMS) are crucial in autonomous driving systems (ADS) when users are concerned about driver/vehicle safety. In DMS, the sign...

Aug 1 2024 39094328
Early predictive values of clinical assessments for ARDS mortality: a machine-learning approach.

Acute respiratory distress syndrome (ARDS) is a devastating critical care syndrome with significant morbidity and mortality. The objective of this stu...

Aug 1 2024 39090217
Enhancing Postmarketing Surveillance of Medical Products With Large Language Models.

IMPORTANCE: The Sentinel System is a key component of the US Food and Drug Administration (FDA) postmarketing safety surveillance commitment and uses ...

Aug 1 2024 39150707
Radiographical diagnostic competences of dental students using various feedback methods and integrating an artificial intelligence application-A randomized clinical trial.

INTRODUCTION: Radiographic diagnostic competences are a primary focus of dental education. This study assessed two feedback methods to enhance learnin...

Jul 31 2024 39082447
Predicting the severity of mood and neuropsychiatric symptoms from digital biomarkers using wearable physiological data and deep learning.

Neuropsychiatric symptoms (NPS) and mood disorders are common in individuals with mild cognitive impairment (MCI) and increase the risk of progression...

Jul 31 2024 39089109
Modeling the Impact of Ergonomic Interventions and Occupational Factors on Work-Related Musculoskeletal Disorders in the Neck of Office Workers with Machine Learning Methods.

BACKGROUND: Modeling with methods based on machine learning (ML) and artificial intelligence can help understand the complex relationships between erg...

Jul 31 2024 39311106
Ultrasound Image Temperature Monitoring Based on a Temporal-Informed Neural Network.

Real-time and accurate temperature monitoring during microwave hyperthermia (MH) remains a critical challenge for ensuring treatment efficacy and pati...

Jul 30 2024 39123982
Diagnostic Accuracy of a Mobile AI-Based Symptom Checker and a Web-Based Self-Referral Tool in Rheumatology: Multicenter Randomized Controlled Trial.

BACKGROUND: The diagnosis of inflammatory rheumatic diseases (IRDs) is often delayed due to unspecific symptoms and a shortage of rheumatologists. Dig...

Jul 23 2024 39042425
A decision support system for the detection of cutaneous fungal infections using artificial intelligence.

Cutaneous fungal infections are one of the most common skin conditions, hence, the burden of determining fungal elements upon microscopic examination ...

Jul 21 2024 39088874
Shaping the future of healthcare in British Columbia: Establishing provincial clinical governance for responsible deployment of artificial intelligence tools.

As healthcare embraces the transformative potential of Artificial Intelligence (AI), it is imperative to safeguard patient and provider safety, equity...

Jul 20 2024 39030752
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