Public Health & Policy

Clinical Trials

Latest AI and machine learning research in clinical trials for healthcare professionals.

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Peripheral artery disease diagnosis based on deep learning-enabled analysis of non-invasive arterial pulse waveforms.

This paper intends to investigate the feasibility of peripheral artery disease (PAD) diagnosis based on the analysis of non-invasive arterial pulse waveforms. We generated realistic synthetic arterial blood pressure (BP) and pulse volume recording (PVR) waveform signals pertaining to PAD present at the abdominal aorta with a wide range of severity levels using a mathematical model that simulates a...

Dec 7 2023 38086141

Data science in drug discovery safety: Challenges and opportunities.

Early de-risking of drug targets and chemistry is essential to provide drug projects with the best chance of success. Target safety assessments (TSAs) use target biology, gene and protein expression data, genetic information from humans and animals, and competitor compound intelligence to understand the potential safety risks associated with modulating a drug target. However, there is a vast amoun...

Dec 7 2023 38062553
Fear-Neuro-Inspired Reinforcement Learning for Safe Autonomous Driving.

Ensuring safety and achieving human-level driving performance remain challenges for autonomous vehicles, especially in safety-critical situations. As ...

Dec 5 2023 37801378
Detection of safety helmet and mask wearing using improved YOLOv5s.

With the advancement of society, ensuring the safety of personnel involved in municipal construction projects, particularly in the context of pandemic...

Dec 5 2023 38049536
How Can the Clinical Aptitude of AI Assistants Be Assayed?

Large language models (LLMs) are exhibiting remarkable performance in clinical contexts, with exemplar results ranging from expert-level attainment in...

Dec 5 2023 38051572
Long-term effects of deep-learning digital therapeutics on pain, movement control, and preliminary cost-effectiveness in low back pain: A randomized controlled trial.

OBJECTIVE: The present study aimed to compare the effects of a deep learning-based digital application with digital application physical therapy (DPT)...

Dec 3 2023 38053732
Effect of robot for medication management on home care professionals' use of working time in older people's home care: a non-randomized controlled clinical trial.

BACKGROUND: Medication management has a key role in the daily tasks of home care professionals delivered to older clients in home care. The aim of thi...

Dec 2 2023 38042773
Pharmacokinetic Profiling of Ginsenosides, Rb1, Rd, and Rg3, in Mice with Antibiotic-Induced Gut Microbiota Alterations: Implications for Variability in the Therapeutic Efficacy of Red Ginseng Extracts.

Ginsenoside Rg3 is reported to contribute to the traditionally known diverse effects of red ginseng extracts. Significant individual variations in the...

Dec 1 2023 38231867
Revolutionizing clinical trials: the role of AI in accelerating medical breakthroughs.

Clinical trials are the essential assessment for safe, reliable, and effective drug development. Data-related limitations, extensive manual efforts, r...

Dec 1 2023 38259001
A Bibliometric Analysis of Neuroscience Tools Use in Construction Health and Safety Management.

Despite longstanding traditional construction health and safety management (CHSM) methods, the construction industry continues to face persistent chal...

Nov 30 2023 38067895
Harnessing the translational power of bleomycin model: new insights to guide drug discovery for idiopathic pulmonary fibrosis.

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, age-related interstitial lung disease (ILD) with limited therapeutic options. Despite ...

Nov 30 2023 38099140
Impact of artificial intelligence on dentists' gaze during caries detection: A randomized controlled trial.

OBJECTIVES: We aimed to understand how artificial intelligence (AI) influences dentists by comparing their gaze behavior when using versus not using a...

Nov 26 2023 38016620
Microfluidic chip as a promising evaluation method in assisted reproduction: A systematic review.

The aim of assisted reproductive technology (ART) is to select the high-quality sperm, oocytes, and embryos, and finally achieve a successful pregnanc...

Nov 24 2023 38435817
Predicting intratumoral fluid pressure and liposome accumulation using physics informed deep learning.

Liposome-based anticancer agents take advantage of the increased vascular permeability and transvascular pressure gradients for selective accumulation...

Nov 23 2023 37996509
Design Method of a Smart Rehabilitation Product Service System Based on Virtual Scenarios: A Case Study.

The development of artificial intelligence and virtual reality technology has enabled rehabilitation service systems based on virtual scenarios to pro...

Nov 21 2023 37966937
Hot topics in allergen immunotherapy, 2023: Current status and future perspective.

The importance of allergen immunotherapy (AIT) is multifaceted, encompassing both clinical and quality-of-life improvements and cost-effectiveness in ...

Nov 20 2023 37984449
Patient safety classifications, taxonomies and ontologies, part 2: A systematic review on content coverage.

BACKGROUND: Content coverage of patient safety ontology and classification systems should be evaluated to provide a guide for users to select appropri...

Nov 18 2023 37984548
Assessment of systemic inflammation following oral calcium supplementation in healthy postpartum multiparous dairy cows-A randomized controlled trial.

Around parturition, dairy cows inevitably and perhaps necessarily experience some degree of systemic inflammation, but when excessive or dysregulated,...

Nov 17 2023 38482115
ChatGPT's Ability to Assist with Clinical Documentation: A Randomized Controlled Trial.

INTRODUCTION: Clinical documentation is a critical aspect of health care that enables healthcare providers to communicate effectively with each other ...

Nov 17 2023 37976385
COVID-19 Vaccination in Liver Cirrhosis: Safety and Immune and Clinical Responses.

INTRODUCTION: Three years after the beginning of the SARS-CoV-2 pandemic, the safety and efficacy of COVID-19 vaccination in liver cirrhosis (LC) pati...

Nov 15 2023 39360169
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