Oncology/Hematology

Colon Cancer

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Clinically-Grounded Counterfactual Reasoning for Medical Video Diagnosis

Medical video diagnosis involves inferring clinical decisions from dynamic tissue responses throughout examination processes. Existing methods rely on an end-to-end learning paradigm that i) focuses on appearance rather than pathology, ii) lacks clinical priors, and iii) reasons solely from observations without counterfactual comparison. This work introduces MedVCR, a counterfactual reasoning fram...

May 26 2026 2605.26483v1

RAPTOR+: A Visually Grounded Vision-Language Framework to Improve Clinical Trust and Auditability in Automated Cancer Referral Processing

Urgent suspected colorectal cancer (CRC) referrals create operational bottlenecks because semi-structured clinical documents often require manual review and transcription. The original RAPTOR system used Large Language Models for structured extraction but relied on a separate OCR stage, making it vulnerable to handwriting, layout variation, and loss of visual evidence linkage. We present RAPTOR+, ...

May 25 2026 2605.25956v1
PathWISE: Multi-Agent Cancer Pathway Triaging Ontology Learning from Clinical Flowcharts

Clinical pathways are disseminated as visual flowcharts where spatial topology, arrow direction, colour coding, and font weight encode critical triage...

May 25 2026 2605.25970v1
Artificial intelligence-driven precision medicine identifies prognostic WNT pathway alterations in AA colorectal cancer patients treated with FOLFOX

Background: African Americans (AA) experience disproportionate burden of colorectal cancer (CRC). Dysregulation of the Wingless-related integration si...

A Multimodal Neural Network Model for Early Recurrence Prediction in Lung Adenocarcinoma

Lung adenocarcinoma (LUAD), a subtype of non-small cell lung cancer (NSCLC), is the most common primary lung cancer worldwide. Despite advancements in...

Patch-MoE Mamba: A Patch-Ordered Mixture-of-Experts State Space Architecture for Medical Image Segmentation

CNN- and Transformer-based architectures have achieved strong performance in medical image segmentation, but CNNs are limited in modeling long-range d...

May 18 2026 2605.17719v1
SurgLQA: Scalable Long-Horizon Surgical Video Question Answering

Surgical Video Question Answering (VideoQA) provides a promising paradigm for dynamic intraoperative interpretation, enabling real-time decision suppo...

May 18 2026 2605.17915v1
Overweight status drives early tumor microenvironment reprogramming in pancreatic ductal adenocarcinoma: a cell-type-resolved Bayesian hierarchical modeling and interactome analysis

Background: Obesity significantly increases the risk of prognosis and clinical outcomes in pancreatic ductal adenocarcinoma (PDAC). While research on ...

STOMAPY: Artificial Intelligence for Risk Stratification of Outcomes Requiring Enterostomal Therapy After Hospital Discharge Following Colorectal Surgery

Introduction: Infectious and wound-healing complications after colorectal surgery often increase the complexity of local care and the need for special...

LATERN: Test-Time Context-Aware Explainable Video Anomaly Detection

Vision-language models (VLMs) have recently emerged as a promising paradigm for video anomaly detection (VAD) due to their strong visual reasoning abi...

May 14 2026 2605.15054v1
Contrastive Learning under Noisy Temporal Self-Supervision for Colonoscopy Videos

Learning robust representations of polyp tracklets is key to enabling multiple AI-assisted colonoscopy applications, from polyp characterization to au...

May 12 2026 2605.12320v1
Medical Imaging Classification with Cold-Atom Reservoir Computing using Auto-Encoders and Surrogate-Driven Training

We introduce a hybrid quantum-classical pipeline, based on neutral-atom reservoir computing, for medical image classification, focusing on the binary ...

May 7 2026 2605.06727v1
Continuous Expert Assembly: Instance-Conditioned Low-Rank Residuals for All-in-One Image Restoration

Real-world image degradation is often unknown, spatially non-uniform, and compositional, requiring all-in-one restoration models to adapt a single set...

May 7 2026 2605.06127v1
Multi-LLM Disagreement as a Scalable Detector of Human Annotation Errors in Structured Data from Clinical Free-Text

Abstract Objective: Structured extraction from clinical free-text depends on human annotators whose labels are susceptible to errors and knowledge-dri...

STAT: A multi-agent framework for integrated and interactive spatial transcriptomics analysis

Spatial transcriptomics analysis often involves a myriad of computational methods across diverse platforms, leading analysts to spend excessive time o...

Interpreting Omics Data Analysis with Large Language Models for Disease Target and Drug Discovery

In biomedical scientific discovery, synthesizing prior knowledge from the literature is an essential component of interpreting numerical omics data an...

Biological Spatial Priors Regularize Foundation Model Representations for Cross-Site MSI Generalization in Colorectal Cancer

Predicting microsatellite instability (MSI) status from routine hematoxylin and eosin (H&E) whole slide images (WSIs) offers a practical alternative t...

May 4 2026 2605.02660v1
Virtual Scanning for NSCLC Histology: Investigating the Discriminatory Power of Synthetic PET

Accurate histological differentiation between adenocarcinoma (ADC) and squamous cell carcinoma (SCC) is critical for personalized treatment in non-sma...

May 4 2026 2605.02746v1
Programming Biomolecular Interactions with All-Atom Generative Model

Biomolecular interactions lie at the core of cellular life, spanning diverse molecular modalities from small molecules to nucleic acids and proteins. ...

Assessing Pancreatic Ductal Adenocarcinoma Vascular Invasion: the PDACVI Benchmark

Surgical resection remains the only potentially curative treatment for pancreatic ductal adenocarcinoma (PDAC), and eligibility depends on accurate as...

Apr 30 2026 2604.27582v1
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