Oncology/Hematology

Colon Cancer

Latest AI and machine learning research in colon cancer for healthcare professionals.

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HealthFormer: Dual-level time-aware Transformers for irregular electronic health record events

Longitudinal electronic health records (EHRs) form irregular event sequences that mix multiple clinical coding systems and care settings. Learning transferable patient representations requires modeling both within-encounter code composition and long-range temporal dependencies. We aim to develop a pretraining framework that preserves event structure and explicitly uses elapsed time, while remainin...

Colon-Bench: An Agentic Workflow for Scalable Dense Lesion Annotation in Full-Procedure Colonoscopy Videos

Early screening via colonoscopy is critical for colon cancer prevention, yet developing robust AI systems for this domain is hindered by the lack of densely annotated, long-sequence video datasets. Existing datasets predominantly focus on single-class polyp detection and lack the rich spatial, temporal, and linguistic annotations required to evaluate modern Multimodal Large Language Models (MLLMs)...

Mar 26 2026 2603.25645v1
Automated Extraction of Cancer Registry Data from Pathology Reports: Comparing LLM-Based and Ontology-Driven NLP Platforms

Cancer data standardization requires converting unstructured pathology reports into structured registry variables, a mostly manual and resource-intens...

Translating Histopathology Foundation Model Embeddings into Cellular and Molecular Features for Clinical Studies

AI-powered pathology foundation models provide general-purpose representations of histopathological images by encoding image tiles into numerical embe...

A vision for a colorectal digital twin that enables proactive and personalized disease management

Colorectal cancer, inflammatory bowel disease, and diverticular disease are progressive conditions that affect millions of individuals worldwide and i...

Mar 18 2026 2603.18064v1
Ablation Study of a Fairness Auditing Agentic System for Bias Mitigation in Early-Onset Colorectal Cancer Detection

Artificial intelligence (AI) is increasingly used in clinical settings, yet limited oversight and domain expertise can allow algorithmic bias and safe...

Mar 17 2026 2603.17179v1
Spectral Rectification for Parameter-Efficient Adaptation of Foundation Models in Colonoscopy Depth Estimation

Accurate monocular depth estimation is critical in colonoscopy for lesion localization and navigation. Foundation models trained on natural images fai...

Mar 16 2026 2603.15374v1
A protocol for evaluating robustness to H&E staining variation in computational pathology models

Sensitivity to staining variation remains a major barrier to deploying computational pathology (CPath) models as hematoxylin and eosin (H&E) staining ...

Mar 13 2026 2603.12886v1
Fair Lung Disease Diagnosis from Chest CT via Gender-Adversarial Attention Multiple Instance Learning

We present a fairness-aware framework for multi-class lung disease diagnosis from chest CT volumes, developed for the Fair Disease Diagnosis Challenge...

Mar 13 2026 2603.12988v1
Unmasking Biases and Reliability Concerns in Convolutional Neural Networks Analysis of Cancer Pathology Images

Convolutional Neural Networks have shown promising effectiveness in identifying different types of cancer from radiographs. However, the opaque nature...

Mar 12 2026 2603.12445v1
CT4CMS: Preoperative Computed Tomography-Based Consensus Molecular Subtyping Prediction in Colorectal Cancer Using Interpretable Deep Learning

Consensus molecular subtyping (CMS) defines the transcriptomic taxonomy of colorectal cancer (CRC) and guides precision therapy. Although current appr...

A Lightweight Multi-Cancer Tumor Localization Framework for Deployable Digital Pathology

Accurate localization of tumor regions from hematoxylin and eosin-stained whole-slide images is fundamental for translational research including spati...

Mar 9 2026 2603.08844v1
Structured Schemas for LLM-Modeler Collaboration in Quantitative Systems Pharmacology Model Calibration

Quantitative systems pharmacology (QSP) models require calibration data from published literature, yet manual curation produces inconsistent documenta...

Weakly Supervised Teacher-Student Framework with Progressive Pseudo-mask Refinement for Gland Segmentation

Background and objectives: Colorectal cancer histopathological grading depends on accurate segmentation of glandular structures. Current deep learning...

Mar 9 2026 2603.08605v1
RPG-SAM: Reliability-Weighted Prototypes and Geometric Adaptive Threshold Selection for Training-Free One-Shot Polyp Segmentation

Training-free one-shot segmentation offers a scalable alternative to expert annotations where knowledge is often transferred from support images and f...

Mar 8 2026 2603.07436v1
BEGA-UNet: Boundary-Explicit Guided Attention U-Net with Multi-Scale Feature Aggregation for Colonoscopic Polyp Segmentation

Accurate polyp segmentation from colonoscopy images is critical for colorectal cancer prevention, yet the generalization of deep learning models under...

LAW & ORDER: Adaptive Spatial Weighting for Medical Diffusion and Segmentation

Medical image analysis relies on accurate segmentation, and benefits from controllable synthesis (of new training images). Yet both tasks of the cycli...

Mar 5 2026 2603.04795v1
Tell2Adapt: A Unified Framework for Source Free Unsupervised Domain Adaptation via Vision Foundation Model

Source Free Unsupervised Domain Adaptation (SFUDA) is critical for deploying deep learning models across diverse clinical settings. However, existing ...

Mar 5 2026 2603.05012v1
Polyp Segmentation Using Wavelet-Based Cross-Band Integration for Enhanced Boundary Representation

Accurate polyp segmentation is essential for early colorectal cancer detection, yet achieving reliable boundary localization remains challenging due t...

Mar 4 2026 2603.03682v1
A multi-center analysis of deep learning methods for video polyp detection and segmentation

Colonic polyps are well-recognized precursors to colorectal cancer (CRC), typically detected during colonoscopy. However, the variability in appearanc...

Mar 4 2026 2603.04288v1
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