Critical Care

Artificial Intelligence Tools for Sepsis and Cancer.

Improving Detection of Early Chronic Obstructive Pulmonary Disease.

Despite being a major cause of morbidity and mortality, chronic obstructive pulmonary disease (COPD) is frequently undiagnosed. Yet the burden of disease among the undiagnosed is significant, as these individuals experience symptoms, exacerbations, and excess mortality compared to those without COPD. The U.S. Preventive Services Task Force recommends against routine screening of asymptomatic indiv...

The role of presepsin in the diagnosis and assessment of severity of sepsis and severe pneumonia.

AIM: The aim of this study was to evaluate marker of inflammation presepsin to improve diagnosis of severe pneumonia, sepsis.

Applying Artificial Intelligence to Identify Physiomarkers Predicting Severe Sepsis in the PICU.

OBJECTIVES: We used artificial intelligence to develop a novel algorithm using physiomarkers to predict the onset of severe sepsis in critically ill c...

Inclusion of Unstructured Clinical Text Improves Early Prediction of Death or Prolonged ICU Stay.

OBJECTIVES: Early prediction of undesired outcomes among newly hospitalized patients could improve patient triage and prompt conversations about patie...

Automated Classification Using End-to-End Deep Learning.

According to a study [1] by the Ministry of Health in Singapore, since 2009, cancer, ischaemic heart disease and pneumonia together accounted for appr...

Early Prediction of Sepsis in EMR Records Using Traditional ML Techniques and Deep Learning LSTM Networks.

Sepsis is a life-threatening condition caused by infection and subsequent overreaction by the immune system. Physicians effectively treat sepsis with ...

Evaluating ICU Clinical Severity Scoring Systems and Machine Learning Applications: APACHE IV/IVa Case Study.

Clinical scoring systems have been developed for many specific applications, yet they remain underutilized for common reasons such as model inaccuracy...

Development and Evaluation of an Automated Machine Learning Algorithm for In-Hospital Mortality Risk Adjustment Among Critical Care Patients.

OBJECTIVES: Risk adjustment algorithms for ICU mortality are necessary for measuring and improving ICU performance. Existing risk adjustment algorithm...

[Application of support vector machine in predicting in-hospital mortality risk of patients with acute kidney injury in ICU].

OBJECTIVE: To construct an in-hospital mortality prediction model for patients with acute kidney injury (AKI) in intensive care unit (ICU) by using su...

An Interpretable Machine Learning Model for Accurate Prediction of Sepsis in the ICU.

OBJECTIVES: Sepsis is among the leading causes of morbidity, mortality, and cost overruns in critically ill patients. Early intervention with antibiot...

[The gender features of disorders of composition of lipids of blood serum in patients with chronic pathology of kidneys.].

The purpose of the study was to investigate gender features of abnormalities of blood serum lipid composition and their relationship with clinical and...

Association of Procalcitonin Value and Bacterial Coinfections in Pediatric Patients With Viral Lower Respiratory Tract Infections Admitted to the Pediatric Intensive Care Unit.

OBJECTIVE: Our primary objective was to determine the utility of procalcitonin (PCT) in detection of bacterial coinfection in children < 5 years admit...

The Effects of Mouth Opening and Throat Pack Placement on Uncuffed Nasal Endotracheal Tube Leakage and Delivered Tidal Volumes in Mechanically Ventilated Pediatric Patients Undergoing Dental Procedures.

Intubation for pediatric patients is frequently performed with an uncuffed endotracheal tube (ETT), which may result in an incomplete tracheal seal, r...

NUTRITIONAL OR ACTIVE VITAMIN D FOR THE CORRECTION OF MINERAL METABOLISM ABNORMALITIES IN NON-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS?

CONTEXT: Benefits of vitamin D therapies in chronic kidney disease (CKD) are debated.

Procalcitonin in inflammatory bowel disease: Drawbacks and opportunities.

The measurement of procalcitonin has recently become a mainstay for the diagnosis and therapeutic management of severe bacterial infections, especiall...

Diet, Lung Function, and Asthma Exacerbations in Puerto Rican Children.

Changes in dietary patterns may partly explain the epidemic of asthma in industrialized countries. The objective of this study was to examine the rela...

The Influence of Intraoperative Autotransfusion on Postoperative Hematocrit after Cardiac Surgery: A Cross-Sectional Study.

Utilization of intraoperative autotransfusion (IAT) during cardiac surgery with cardiopulmonary bypass (CPB) has been shown to reduce allogeneic red b...

Serum 25-hydroxyvitamin D levels in patients with Granulomatosis with Polyangiitis: association with respiratory infection.

OBJECTIVES: To determine the possible association of serum 25-hydroxyvitamin D (25OHD) levels with disease activity and respiratory infection in granu...

[Construction and identification of nanobody phage display library targeting Middle East respiratory syndrome coronavirus].

Objective To construct a phage display library of specific nano-antibodies against the Middle East respiratory syndrome coronavirus (MERS-CoV) and app...