Depression

MicroRNA classification and discovery for major depressive disorder diagnosis: Towards a robust and interpretable machine learning approach.

BACKGROUND: Major depressive disorder (MDD) is notably underdiagnosed and undertreated due to its complex nature and subjective diagnostic methods. Biomarker identification would help provide a clearer understanding of MDD aetiology. Although machine learning (ML) has been implemented in previous studies to study the alteration of microRNA (miRNA) levels in MDD cases, clinical translation has not ...

Construction of an antidepressant priority list based on functional, environmental, and health risks using an interpretable mixup-transformer deep learning model.

As emerging pollutants, antidepressants (AD) must be urgently investigated for risk identification and assessment. This study constructed a comprehensive-effect risk-priority screening system (ADRank) for ADs by characterizing AD functionality, occurrence, persistence, bioaccumulation and toxicity based on the integrated assignment method. A classification model for ADs was constructed using an im...

A novel machine learning-based prediction method for patients at risk of developing depressive symptoms using a small data.

The prediction of depression is a crucial area of research which makes it one of the top priorities in mental health research as it enables early inte...

Identifying Cardiovascular Disease Risk Endotypes of Adolescent Major Depressive Disorder Using Exploratory Unsupervised Machine Learning.

OBJECTIVE: Adolescents with major depressive disorder (MDD) are at increased risk of premature atherosclerosis and cardiovascular disease (CVD). The a...

Risk prediction models of depression in older adults with chronic diseases.

BACKGROUND: Detecting potential depression and identifying the critical predictors of depression among older adults with chronic diseases are essentia...

Study of a PST-trained voice-enabled artificial intelligence counselor for adults with emotional distress (SPEAC-2): Design and methods.

BACKGROUND: Novel and scalable psychotherapies are urgently needed to address the depression and anxiety epidemic. Leveraging artificial intelligence ...

Machine Learning-Based Prediction of Suicidal Thinking in Adolescents by Derivation and Validation in 3 Independent Worldwide Cohorts: Algorithm Development and Validation Study.

BACKGROUND: Suicide is the second-leading cause of death among adolescents and is associated with clusters of suicides. Despite numerous studies on th...

An integrated machine learning framework for developing and validating a diagnostic model of major depressive disorder based on interstitial cystitis-related genes.

BACKGROUND: Major depressive disorder (MDD) and interstitial cystitis (IC) are two highly debilitating conditions that often coexist with reciprocal e...

A machine learning approach to detect potentially harmful and protective suicide-related content in broadcast media.

Suicide-related media content has preventive or harmful effects depending on the specific content. Proactive media screening for suicide prevention is...

Stigma, Support, and Ideation About Suicide in Indonesian Twitter: A Topic Modelling Study.

Stigma surrounding suicide is a massive problem in Indonesia. Thus, it is important to study how conversations about suicide take place. We take a mac...

A machine-learning approach to model risk and protective factors of vulnerability to depression.

There are multiple risk and protective factors for depression. The association between these factors with vulnerability to depression is unclear. Such...

Machine learning approach for the development of a crucial tool in suicide prevention: The Suicide Crisis Inventory-2 (SCI-2) Short Form.

The Suicide Crisis Syndrome (SCS) describes a suicidal mental state marked by entrapment, affective disturbance, loss of cognitive control, hyperarous...

Predictive Models for Suicide Attempts in Major Depressive Disorder and the Contribution of : A Pilot Integrative Machine Learning Study.

Suicide is a major public health problem caused by a complex interaction of various factors. Major depressive disorder (MDD) is the most prevalent psy...

Twenty-four-hour physical activity patterns associated with depressive symptoms: a cross-sectional study using big data-machine learning approach.

BACKGROUND: Depression is a global burden with profound personal and economic consequences. Previous studies have reported that the amount of physical...

Spectral Graph Neural Network-Based Multi-Atlas Brain Network Fusion for Major Depressive Disorder Diagnosis.

Major Depressive Disorder (MDD) imposes a substantial burden within the healthcare domain, impacting millions of individuals worldwide. Functional Mag...

Sexual and Gender Minority Status and Suicide Mortality: An Explainable Artificial Intelligence Analysis.

Suicide risk is elevated in lesbian, gay, bisexual, and transgender (LGBT) individuals. Limited data on LGBT status in healthcare systems hinder our ...

Emerging Trends of Self-Harm Using Sodium Nitrite in an Online Suicide Community: Observational Study Using Natural Language Processing Analysis.

BACKGROUND: There is growing concern around the use of sodium nitrite (SN) as an emerging means of suicide, particularly among younger people. Given t...

Artificial Intelligence and the National Violent Death Reporting System: A Rapid Review.

As the awareness on violent deaths from guns, drugs, and suicides emerges as a public health crisis in the United States, attempts to prevent injury a...

Emergency department risk model: timely identification of patients for outpatient care coordination.

OBJECTIVE: Major depressive disorder (MDD) is linked to a 61% increased risk of emergency department (ED) visits and frequent ED usage. Collaborative ...

Research on a machine learning-based adaptive and efficient screening model for psychological symptoms of community correctional prisoners.

Community correction institutions in China frequently employ the Symptom Checklist-90 (SCL-90) and the health survey brief (SF-12) as primary tools fo...