Dermatology

Effects of protein hydrolysate from chicken feather meal on tyrosinase activity and melanin formation in B16F10 murine melanoma cells.

Tyrosinase is a copper-containing enzyme that controls mammalian melanogenesis. Tyrosinase inhibitors are important for their potential application in cosmetic products. Chicken feather meal is a rich source of amino acids, which have been linked with tyrosinase inhibition activity. This study investigated the tyrosinase inhibitory properties of protein hydrolysates prepared from chicken feather m...

Automated Breast Ultrasound Lesions Detection Using Convolutional Neural Networks.

Breast lesion detection using ultrasound imaging is considered an important step of computer-aided diagnosis systems. Over the past decade, researchers have demonstrated the possibilities to automate the initial lesion detection. However, the lack of a common dataset impedes research when comparing the performance of such algorithms. This paper proposes the use of deep learning approaches for brea...

Coronary Computed Tomographic Angiography-Derived Fractional Flow Reserve Based on Machine Learning for Risk Stratification of Non-Culprit Coronary Narrowings in Patients with Acute Coronary Syndrome.

This study investigated the prognostic value of coronary computed tomography angiography (cCTA)-derived fractional flow reserve (CT-FFR) in patients w...

Machine learning workflow to enhance predictions of Adverse Drug Reactions (ADRs) through drug-gene interactions: application to drugs for cutaneous diseases.

Adverse drug reactions (ADRs) pose critical public health issues, affecting over 6% of hospitalized patients. While knowledge of potential drug-drug i...

Fully automatic acute ischemic lesion segmentation in DWI using convolutional neural networks.

Stroke is an acute cerebral vascular disease, which is likely to cause long-term disabilities and death. Acute ischemic lesions occur in most stroke p...

Detection of Nocturnal Scratching Movements in Patients with Atopic Dermatitis Using Accelerometers and Recurrent Neural Networks.

Atopic dermatitis is a chronic inflammatory skin condition affecting both children and adults and is associated with pruritus. A method for objectivel...

and cell-based analyses reveal strong divergence between prediction and observation of T-cell-recognized tumor antigen T-cell epitopes.

Tumor exomes provide comprehensive information on mutated, overexpressed genes and aberrant splicing, which can be exploited for personalized cancer i...

Personalized Age Progression with Bi-Level Aging Dictionary Learning.

Age progression is defined as aesthetically re-rendering the aging face at any future age for an individual face. In this work, we aim to automaticall...

Deep image mining for diabetic retinopathy screening.

Deep learning is quickly becoming the leading methodology for medical image analysis. Given a large medical archive, where each image is associated wi...

Disseminated cutaneous histoplasmosis with laryngeal involvement in a setting of immune reconstitution inflammatory syndrome.

INTRODUCTION: Histoplasmosis is a systemic mycosis caused by the dimorphic fungus . We report a case of disseminated cutaneous histoplasmosis with muc...

Improving automated multiple sclerosis lesion segmentation with a cascaded 3D convolutional neural network approach.

In this paper, we present a novel automated method for White Matter (WM) lesion segmentation of Multiple Sclerosis (MS) patient images. Our approach i...

Hepatitis B reactivation in psoriasis patients treated with anti-TNF agents: prevention and management.

The risk of hepatitis B virus (HBV) reactivation (HBVr) in chronic HBV carriers, in occult HBV patients or in acute HBV patients affected by psoriasis...

Comparative study of ANN and RSM for simultaneous optimization of multiple targets in Fenton treatment of landfill leachate.

In this study, two modeling methods, namely response surface methodology (RSM) and artificial neural networks (ANN), were applied to investigate the F...

Effect of the vascularized bone components on the survival of vascularized composite allografts.

BACKGROUND: Vascularized composite allograft (VCA), such as hand and face allograft, contains a vascularized bone component that may provide an immuno...

Machine learning based compartment models with permeability for white matter microstructure imaging.

Some microstructure parameters, such as permeability, remain elusive because mathematical models that express their relationship to the MR signal accu...

Evaluation of Association Between the Serum Levels of MMP-9 and MMP-9/TIMPs With Soluble Forms of Selectins and Itching Induced by Sulfur Mustard.

BACKGROUND & OBJECTIVE: Pruritus is the most frequent chronic dermal complication of sulfur mustard (SM), which negatively influences the quality of l...

Dermatologist-level classification of skin cancer with deep neural networks.

Skin cancer, the most common human malignancy, is primarily diagnosed visually, beginning with an initial clinical screening and followed potentially ...

Kinetics Extraction Modelling and Antiproliferative Activity of Water Extract.

is widely grown in tropical Asia and locally known "belalai gajah" or Sabah snake grass. It has been used as a natural product to treat skin rashes, ...

Decision making under uncertainty in a spiking neural network model of the basal ganglia.

The mechanisms of decision-making and action selection are generally thought to be under the control of parallel cortico-subcortical loops connecting ...

ANA-Negative Presentation of SLE in Man with Severe Autoimmune Neutropenia.

. Systemic lupus erythematosus (SLE) is a chronic, inflammatory, connective tissue disease that commonly affects the joints and a variety of organs du...