Dermatology

Surgery for predominant lesion in nonlocalized bronchiectasis.

OBJECTIVE: Patients with nonlocalized bronchiectasis are encountered commonly; however, there is little information regarding surgical intervention in this patient population. The aim of this study was to evaluate symptomatic response and safety of anatomic resection of the predominant lesion via the use of lobectomy for the management of nonlocalized bronchiectasis.

An ecofriendly green liquid chromatographic method for simultaneous determination of nicotinamide and clindamycin phosphate in pharmaceutical gel for acne treatment.

A new green micellar liquid chromatographic method was developed and validated for the quantitative estimation of nicotinamide (NICO) and clindamycin phosphate (CLD) in bulk and pharmaceutical gel formulation. The analytes are well resolved in less than 6.0 minutes using micellar mobile phase consisting of 0.10M sodium dodecyl sulfate (SDS), 0.3% triethylamine, and 10% 2-propanol in 0.02M orthopho...

Melanoma Classification on Dermoscopy Images Using a Neural Network Ensemble Model.

We develop a novel method for classifying melanocytic tumors as benign or malignant by the analysis of digital dermoscopy images. The algorithm follow...

Injection Adipolysis: Mechanisms, Agents, and Future Directions.

Noninvasive procedures targeting the elimination of unwanted adipose tissues have recently been developed. injection adipolysis is the term for the in...

Efficacy according to blind independent central review: Post-hoc analyses from the phase III, randomized, multicenter, IPASS study of first-line gefitinib versus carboplatin/paclitaxel in Asian patients with EGFR mutation-positive advanced NSCLC.

OBJECTIVE: The Phase III, randomized, open-label IPASS study (NCT00322452) of first-line epidermal growth factor receptor tyrosine kinase inhibitor (E...

Prediction of microRNAs involved in immune system diseases through network based features.

MicroRNAs are a class of small non-coding regulatory RNA molecules that modulate the expression of several genes at post-transcriptional level and pla...

Growth of Uveal Melanoma following Intravitreal Bevacizumab.

PURPOSE: Typically treatment of large melanomas (by Collaborative Ocular Melanoma Study criteria) is restricted to enucleation, due to size constraint...

Adaptive Estimation of Active Contour Parameters Using Convolutional Neural Networks and Texture Analysis.

In this paper, we propose a generalization of the level set segmentation approach by supplying a novel method for adaptive estimation of active contou...

Vitamin E (α-Tocopherol) Exhibits Antitumour Activity on Oral Squamous Carcinoma Cells ORL-48.

Cancers involving the oral cavity, head, and neck regions are often treated with cisplatin. In cancer therapy, the main target is to eliminate unwante...

Adipose tissue-derived stem cells ameliorates dermal fibrosis in a mouse model of scleroderma.

OBJECTIVE: To investigate the therapeutic potential of adipose-derived stem cells (ADSCs) for limited cutaneous scleroderma (LS) in mouse models.

High Interleukin 27 Production is Associated with Early Clinical Stage and Localized Disease in Patients with Melanoma.

BACKGROUND: The immune response in patients with melanoma is an important focus of research due to the tumor's resistance and immunotherapy possibilit...

Differential Diagnosis of Erythmato-Squamous Diseases Using Classification and Regression Tree.

INTRODUCTION: Differential diagnosis of Erythmato-Squamous Diseases (ESD) is a major challenge in the field of dermatology. The ESD diseases are place...

Efficient multi-scale 3D CNN with fully connected CRF for accurate brain lesion segmentation.

We propose a dual pathway, 11-layers deep, three-dimensional Convolutional Neural Network for the challenging task of brain lesion segmentation. The d...

Virtual screening of natural compounds as inhibitors of EGFR 696-1022 T790M associated with non-small cell lung cancer.

Non-small cell lung cancer (NSCLC) is the most dominating and lethal type of lung cancer triggering more than 1.3 million deaths per year. The most ef...

Indications, technique, and results of robotic pancreatoduodenectomy.

Robotic assistance improves surgical dexterity in minimally invasive operations, especially when fine dissection and multiple sutures are required. As...

Cytotoxic and Antimicrobial Constituents from the Essential Oil of Lippia alba (Verbenaceae).

(Verbenaceae) is a plant widely used in folk medicine to treat various diseases. The present work deals with the chemical composition of the crude es...

Ten problems and solutions when predicting individual outcome from lesion site after stroke.

In this paper, we consider solutions to ten of the challenges faced when trying to predict an individual's functional outcome after stroke on the basi...

Decoding post-stroke motor function from structural brain imaging.

Clinical research based on neuroimaging data has benefited from machine learning methods, which have the ability to provide individualized predictions...

Random Bits Forest: a Strong Classifier/Regressor for Big Data.

Efficiency, memory consumption, and robustness are common problems with many popular methods for data analysis. As a solution, we present Random Bits ...

Composition of Asarum heterotropoides var. mandshuricum radix oil from different extraction methods and activities against human body odor-producing bacteria.

In this study, oils from Asarum heterotropoides were extracted by traditional solvent extraction and supercritical CO (SC-CO) extraction methods and t...