Dermatology

Latest AI and machine learning research in dermatology for healthcare professionals.

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Subcategories: Atopy Psoriasis
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Automated Melanocytic Lesion Classification: Capsule Networks Trained With Synthetic Images Can Outperform Networks Trained With Real Images.

BACKGROUND/OBJECTIVES: Convolutional neural networks (CNNs) are known, due to inherent flaws in their design, to be subject to classification error. Many of these shortcomings in classification performance were addressed in 2017 with the introduction of capsule networks (CNs). The objective of this investigation is to determine the classification performance of a CN with respect to dermoscopic ima...

Feb 24 2026 41736182

Dynamic lysine acetylation and succinylation of platelet proteins regulates platelet storage lesion: mechanistic insights from multi-omics.

OBJECTIVES: Platelet storage lesion (PSL) severely impairs platelet function during storage, presenting a major hurdle in transfusion medicine; however, the dynamic interplay between global proteomic changes and post-translational modifications (PTMs) underlying these functional deteriorations remains insufficiently characterized. Here, we report the first comprehensive multi-omics analysis integr...

Feb 23 2026 41729159
Breaking resistance in BRAF-mutant Melanoma: Novel strategies and biomarkers for optimizing targeted therapies.

In metastatic melanoma with a BRAFV600 mutation, inhibitors of BRAF and MEK have improved survival. Resistance may be acquired through late genetic al...

Feb 23 2026 41740779
Comparison of respiratory-gated and breath‑hold accelerated T2-weighted sequences for liver MRI with deep learning reconstruction.

BACKGROUND: T2-weighted imaging (T2WI) of the liver suffers from prolonged scan times and respiratory motion artifacts. Deep learning (DL)-based recon...

Feb 23 2026 41729404
The emerging role of antibody-drug conjugates in EGFR-mutant non-small cell lung cancer with acquired resistance to third-generation EGFR tyrosine kinase inhibitors.

Resistance to third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) presents a significant clinical challenge for...

Feb 21 2026 41730505
Immunotherapy in Triple-Negative Breast Cancer: From Molecular Mechanisms to Precision Medicine-Overcoming Resistance and Optimizing Clinical Outcomes.

Triple-negative breast cancer (TNBC) is the most violent type of breast cancer, in which estrogen receptors (ER), progesterone receptors (PR), and hum...

Feb 20 2026 41724338
Standardizing case definitions for hoof lesions and lameness: A scoping review to improve machine learning applications in dairy cattle.

Lameness in dairy cattle, primarily caused by hoof lesions, remains a widespread issue in North America with significant welfare, economic, and sustai...

Feb 20 2026 41724468
Engineered Living Systems With Self-Organizing Neural Networks: From Anatomy to Behavior and Gene Expression.

A great deal is known about the formation and architecture of biological neural networks in animal models, which have arrived at their current structu...

Feb 20 2026 41717829
Vision transformer-based diagnosis of psoriasis and eczema in whole-slide histology.

Psoriasis and eczema are chronic inflammatory skin diseases with overlapping histopathological features, which often lead to diagnostic uncertainty ev...

Feb 20 2026 41714431
Skin deep: dermatologic challenges in PCOS through the female lifespan.

INTRODUCTION: Polycystic ovary syndrome (PCOS) is a lifelong endocrine-metabolic condition with prominent dermatologic manifestations such as hirsutis...

Feb 19 2026 41715888
Dual-Parallel Artificial Intelligence Framework for Breast Cancer Grading via High-Intensity Ultrasound and Biomarkers.

BACKGROUND: Accurate and noninvasive breast cancer grading and therapy monitoring remain critical challenges in oncology. Traditional methods often re...

Feb 19 2026 41027412
Clinical Factors Associated With Current Relevance in Allergic Contact Dermatitis: Development of Predictive Models Based on Data From the Spanish Contact Dermatitis Register (REIDAC).

BACKGROUND: Current relevance of positive patch-test reactions guides management in allergic contact dermatitis (ACD), yet its clinical predictors and...

Feb 19 2026 41714111
Concurrent driver mutations induce distinct tumour morphologies on radiological imaging.

BACKGROUND: Most radiogenomic studies examine single driver mutations in isolation, despite evidence that co-occurring driver alterations are common a...

Feb 18 2026 41759448
Novel Systemic Associations of Idiopathic Epiretinal Membrane Identified via Machine Learning.

PURPOSE: To discover novel systemic associations that may lead to idiopathic epiretinal membrane (iERM) using interpretable machine learning models. D...

Feb 18 2026 41908500
Multiharmonic imaging-based automated recognition of cutaneous T-cell lymphoma.

BACKGROUND: Cutaneous T-cell lymphomas (CTCLs) are a heterogeneous group of non-Hodgkin lymphomas, with mycosis fungoides (MF) being the most common t...

Feb 18 2026 40906883
Three dimensional total body photography identifies cutaneous phenotypes associated with late-onset invasive melanoma risk.

BACKGROUND: High naevus counts and ultraviolet photodamage are strong risk factors for melanoma. However, whole-of-body measures fail to capture varia...

Feb 18 2026 41183492
Optimization and External Validation of a Deep Learning Model for Segmentation and Quantification of Traumatic Brain Injury Lesions on Head Computed Tomography.

Current methods for radiological classification in traumatic brain injury (TBI), such as the Marshall and Rotterdam score, provide an incomplete descr...

Feb 18 2026 41705651
Lesion-level dual-tracer PET biomarkers predict prognosis in multiple myeloma treated with CXCR4-directed radiopharmaceutical therapy.

BACKGROUND: C-X-C motif chemokine receptor 4 (CXCR4)-directed radiopharmaceutical therapy (RPT) represents a promising option for hematologic malignan...

Feb 18 2026 41706122
Adaptive example selection for prototype based explainable mitosis detection in digital pathology.

Understanding the decision-making process of black-box neural networks is crucial for safe use of AI in high-stakes medical tasks such as histopatholo...

Feb 18 2026 41708713
Artificial intelligence-based smartphone application for skin cancer detection: A prospective diagnostic accuracy study.

BACKGROUND: Smartphone applications that use artificial intelligence (AI) for skin cancer diagnosis may assist in early detection. However, prospectiv...

Feb 17 2026 41701029
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