Diabetes

DRPM: An advanced predictive model for early diabetes detection and risk stratification.

Diabetes is a prevalent chronic disease that poses a significant burden on individuals and healthcar...

A Comprehensive Workflow for Imaging Live Insulin Secretion Events and Granules in Intact Islets.

Accurate detection of insulin secretion from pancreatic beta cells is crucial for understanding norm...

A bidirectional reasoning approach for blood glucose control via invertible neural networks.

BACKGROUND AND OBJECTIVE: Despite the profound advancements that deep learning models have achieved ...

Tilorone attenuates high-fat diet-induced hepatic steatosis by enhancing BMP9-Smad1/5/8 signaling.

The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) is rapidly increa...

Machine learning and deep learning in diabetology: revolutionizing diabetes care.

Type 2 Diabetes in Taiwan: Unmasking Influential Factors Through Advanced Predictive Modeling.

Type 2 diabetes (T2D) is influenced by lifestyle, genetics, and environmental conditions. By utiliz...

Regression and machine learning approaches identify potential risk factors for glioblastoma multiforme.

Glioblastoma multiforme is a lethal disease, with a 5-year survival rate of <10%. The identification...

EEG microstate analysis in trigeminal neuralgia: identifying potential biomarkers for enhanced diagnostic accuracy.

OBJECTIVE: This study investigated EEG microstate dynamics in trigeminal neuralgia (TN) patients to ...

Early detection of retinal and choroidal microvascular impairments in diabetic patients with myopia.

PURPOSE: To evaluate and quantify diabetes-related retinal and choroid perfusion changes in individu...

Continuous glucose monitoring combined with artificial intelligence: redefining the pathway for prediabetes management.

Prediabetes represents an early stage of glucose metabolism disorder with significant public health ...

[Automated diabetic retinopathy screening in out-patient diabetes care - comparison of two artificial intelligence algorithms RetCAD and OphtAI].

Mechanisms underlying obesity-malignancy connection: a systematic narrative review.

The association between obesity and cancer risk carries substantial public health ramifications as o...

Cost-effectiveness of the 3E model in diabetes management: a machine learning approach to assess long-term economic impact.

BACKGROUND: This study investigated the cost-effectiveness and clinical impact of the 3E model (educ...

Identification of biomarkers and potential drug targets in DFU based on fundamental experiments and multi-omics joint analysis.

OBJECTIVE: This study aims to investigate the molecular mechanisms by which quercetin facilitates th...

Impact of hyperglycaemia on cellular microenvironment and function of endometrium and uterine tube: scoping review focused on infertility in diabetic women.

INTRODUCTION: Diabetes mellitus (DM) and associated comorbidities correspond to female infertility b...

Cardiovascular, Kidney, Liver, and Metabolic Interactions in Heart Failure: Breaking Down Silos.

Over the past few decades, the rising burden of metabolic disease, including type 2 diabetes, predia...

Design, synthesis, and evaluation of triazolo[1,5-a]pyridines as novel and potent α‑glucosidase inhibitors.

α-Glucosidase is a key enzyme responsible for controlling the blood glucose, making a pivotal target...

Artificial Intelligence-Based Detection of Diabetic Retinopathy-Reply.

Artificial Intelligence-Based Detection of Diabetic Retinopathy.

The Role of HbA1c in Parkinson's Disease: An Integrative Analysis by Single-Cell, Bulk Transcriptome and Mendelian Randomization.

Decreased glucose tolerance is recognized as a factor associated with Parkinson's disease (PD) progr...

Resting-State Functional MRI Reveals Altered Seed-Based Connectivity in Diabetic Osteoporosis Patients.

BACKGROUND: Diabetic osteoporosis (DOP) can cause abnormal brain neural activity, but its mechanism ...