Diabetes

Serum osteocalcin levels are inversely associated with the presence of nonalcoholic fatty liver disease in patients with coronary artery disease.

Osteocalcin plays roles in energy, glucose, and lipid metabolism. Consequently, the relationship between osteocalcin level and nonalcoholic fatty liver disease (NAFLD) is of interest. The present study explored the possible correlation between serum osteocalcin levels and NAFLD in patients with CAD. The study enrolled 174 inpatients diagnosed with CAD by coronary angiography (CAG). The presence of...

Effect of blood pressure and glycemic control on the plasma cell-free DNA in hemodialysis patients.

BACKGROUND: The plasma levels of cell-free DNA (cfDNA) are known to be elevated under inflammatory or apoptotic conditions. Increased cfDNA levels have been reported in hemodialysis (HD) patients. The aim of this study was to investigate the clinical significance of cfDNA in HD patients.

Machine Learning Approaches for Detecting Diabetic Retinopathy from Clinical and Public Health Records.

INTRODUCTION: Annual eye examinations are recommended for diabetic patients in order to detect diabetic retinopathy and other eye conditions that aris...

Influence of protein kinase C (PKC) on the prognosis of diabetic nephropathy patients.

AIMS: To investigate the association between protein kinase C (PKC) and the prognosis of patients with diabetic nephropathy (DN).

Changes in brain ribonuclease (BRB) messenger RNA in granulosa cells (GCs) of dominant vs subordinate ovarian follicles of cattle and the regulation of BRB gene expression in bovine GCs.

Brain ribonuclease (BRB) is a member of the ribonuclease A superfamily that is constitutively expressed in a range of tissues and is the functional ho...

Glutathione peroxidase-1 gene (GPX1) variants, oxidative stress and risk of kidney complications in people with type 1 diabetes.

BACKGROUND AND AIM: Glutathione peroxidase (GPX) is a class of antioxidant enzymes that catalyze the reduction of hydrogen peroxide to water. GPX1 is ...

A linear functional strategy for regularized ranking.

Regularization schemes are frequently used for performing ranking tasks. This topic has been intensively studied in recent years. However, to be effec...

Bioequivalence of fixed-dose combinations of dapagliflozin and metformin with single-component tablets in healthy subjects and the effect of food on bioavailability.

The pharmacokinetics (PK) of dapagliflozin and metformin administered as fixed-dose combination (FDC) tablets (2.5 mg dapagliflozin/850 mg metformin o...

Aggressive hydraTion in patients with ST-Elevation Myocardial infarction undergoing Primary percutaneous coronary intervention to prevenT contrast-induced nephropathy (ATTEMPT): Study design and protocol for the randomized, controlled trial, the ATTEMPT, RESCIND 1 (First study for REduction of contraSt-induCed nephropathy followINg carDiac catheterization) trial.

Adequate hydration is recommended for acute ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention ...

Ginsenoside Rg1 Improves In vitro-produced Embryo Quality by Increasing Glucose Uptake in Porcine Blastocysts.

Ginsenoside Rg1 is a natural compound with various efficacies and functions. It has beneficial effects on aging, diabetes, and immunity, as well as an...

Pharmacokinetic and bioavailability study of angeloylgomisin H in rat plasma by UPLC-MS/MS.

Angeloylgomisin H, as a major lignin in the fruits, was reported to have the potential to improve insulin-stimulated glucose uptake by activating PPAR...

Bioequivalence and comparative pharmacodynamics of insulin lispro 200 U/mL relative to insulin lispro (Humalog®) 100 U/mL.

Insulin lispro 200 U/mL (IL200) is a new strength formulation of insulin lispro (Humalog®, IL100), developed as an option for diabetic patients on hig...

Creation of a new longitudinal corpus of clinical narratives.

The 2014 i2b2/UTHealth Natural Language Processing (NLP) shared task featured a new longitudinal corpus of 1304 records representing 296 diabetic pati...

A context-aware approach for progression tracking of medical concepts in electronic medical records.

Electronic medical records (EMRs) for diabetic patients contain information about heart disease risk factors such as high blood pressure, cholesterol ...

Robots and type 1 diabetes.

Robotically assisted percutaneous coronary intervention: benefits to the patient and the cardiologist.

Robotic percutaneous interventional systems represent the future of interventional cardiology. Robotic technology significantly reduces operator expos...

Stress Testing of an Artificial Pancreas System With Pizza and Exercise Leads to Improvements in the System's Fuzzy Logic Controller.

BACKGROUND: Under controlled conditions, the Dose Safety artificial pancreas (AP) system controller, which utilizes "fuzzy logic" (FL) methodology to ...

Comparison of UMLS terminologies to identify risk of heart disease using clinical notes.

The second track of the 2014 i2b2 challenge asked participants to automatically identify risk factors for heart disease among diabetic patients using ...

Adapting existing natural language processing resources for cardiovascular risk factors identification in clinical notes.

The 2014 i2b2 natural language processing shared task focused on identifying cardiovascular risk factors such as high blood pressure, high cholesterol...

Coronary artery disease risk assessment from unstructured electronic health records using text mining.

Coronary artery disease (CAD) often leads to myocardial infarction, which may be fatal. Risk factors can be used to predict CAD, which may subsequentl...