Endocrinology

Diabetes

Latest AI and machine learning research in diabetes for healthcare professionals.

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MetaboNet-Bench: A Multi-modal Benchmark for Glucose Forecasting in Type 1 Diabetes

Glucose forecasting algorithms are an important aspect of glycemic control management in type 1 diabetes. So far, the research community has developed numerous algorithms and models for forecasting. However, it is well-recognized that the lack of standardized model performance evaluation benchmarks makes fair comparison difficult and hinders further innovation, and thus benchmark standardization i...

Jun 17 2026 2606.18640v1

Context-Aware Optimization of Follow-Up Intervals for Type 2 Diabetes Care Using Markov Decision Processes

Chronic disease management relies on regular patient-provider interactions to follow-up on disease progression and control. For Type 2 Diabetes (T2D), current guidelines prescribe fixed time intervals between subsequent primary care visits for all patients, overlooking heterogeneity in clinical trajectories and patient characteristics. This study introduces a Contextual Markov Decision Process (CM...

Jun 17 2026 2606.19092v1
A Multi-Center Benchmark for Abdominal Disease Diagnosis and Report Generation from Non-Contrast CT

Multiphasic contrast-enhanced CT (CECT) is widely used for abdominal lesion characterization, yet it carries inherent risks of contrast-induced nephro...

Jun 15 2026 2606.16991v1
Beyond the Blood Draw: Explainable Machine Learning for Non-Invasive Dysglycemia Risk Screening

Dysglycemia, encompassing both prediabetes and diabetes, affects huge numbers of adults worldwide, yet many of them remain undiagnosed. We developed a...

Jun 14 2026 2606.16056v1
OmicsNavigator: An auditable scientific partner for scalable hypothesis validation in spatial omics

Translating high-dimensional, spatially resolved molecular datasets into testable biological findings remains a major research bottleneck. Here, we pr...

Systematic AI-Driven Drug Repurposing via Clinical Trial Data Mining: A Framework and Six Cross-Therapeutic Case Studies.

Drug repurposing, the application of approved or shelved compounds to new therapeutic indications, offers a cost- and time-efficient alternative to de...

Order-Based Bayesian Network Modeling of Early Detection and Post-Diagnosis Control for Cardiovascular Disease Risk in Type 2 Diabetes

Patients diagnosed with type 2 diabetes (T2D) are at increased risk of developing cardiovascular disease (CVD), the leading cause of morbidity and mor...

LLM-Powered Personalized Glycemic Assessment in Type 2 Diabetes with Wearable Sensor Data

Type 2 Diabetes (T2D) poses an increasing global health threat, demanding effective glycemic assessment to support personalized and improved diabetes ...

Jun 10 2026 2606.12699v1
Transcriptomic Architecture of Type 2 Diabetes in Human Pancreatic Islets:An Integrative Meta-Analysis and Machine Learning Framework for Biomarker Discovery

Background. Type 2 diabetes mellitus (T2D) is defined by progressive pancreatic {beta}-cell dysfunction whose molecular underpinnings remain incomplet...

Optimisation of steatotic liver disease screening algorithm for resource-poor settings using machine learning

Background The European Association for the Study of the Liver (ESAL) - Steatotic Liver Disease (SLD) screening algorithm involves two steps; initial ...

Real-world safety profile of Enfortumab Vedotin: A comprehensive pharmacovigilance analysis based on the FDA Adverse Event Reporting System (FAERS)

Background: This study aimed to evaluate real-world adverse event (AE) signals of EV to provide evidence-based guidance for its safe clinical applicat...

AI-guided analysis of human pancreatic islet sociology reveals distinct cell compositional changes in type 1 diabetes

Human pancreatic islets exhibit greater anatomic and cellular heterogeneity than previously appreciated, raising fundamental questions about how their...

MetaPlate: Counterfactual-Guided RAG-LLM Tool for Personalized Food Recommendation and Hyperglycemia Prevention

Postprandial hyperglycemia is a key risk factor for metabolic disorders; however, existing dietary guidance is often static, impractical, and insuffic...

Jun 8 2026 2606.10120v1
A hierarchical clinical fusion transformer model for personalized opioid treatment: Development and validation in diabetic surgical patients

Background Machine learning (ML) models are increasingly used to predict adverse outcomes after surgery. However, most rely on static patient characte...

Automated Retinal Dysplasia Segmentation in Mouse Optical Coherence Tomography Scans Using a UNet-Based model

Optical coherence tomography (OCT) is the state-of-the-art non-invasive imaging technique for preclinical retinopathy studies. However, manual patholo...

MealRes-Gate: Forecasting Glucose Dynamics from CGM and Sparse Meal Logs Using Residual-Gated Multimodal Transformer

Continuous glucose monitoring (CGM) enables personalized metabolic health support, but forecasting glucose in free-living settings remains challenging...

Deep Longitudinal Clusters of Type 2 Diabetes Pathophysiology and their Risk of Cardiovascular Disease Events and All-Cause Mortality

Objective: Despite the complex and non-linear progression of diabetes, its shared pathways with atherosclerotic cardiovascular disease (ASCVD) are con...

A Deep Learning-Based Predictive Algorithm for Metabolic Syndrome Detection in the U.S. Population

Objective To develop clinically operational, population-representative risk-score models for detecting metabolic syndrome (MetS) in U.S. adults by inc...

Neovascular Glaucoma at a Tertiary Centre in Finland, 2008-2024: A Retrospective Cohort Study

Background/Aims: Neovascular glaucoma (NVG) is an aggressive secondary glaucoma with limited longitudinal data. This study reports the aetiologies, tr...

Boundary-Specific Failure Modes and Safety Trade-offs of Large Language Models in ChronicKidney Disease Renoprotective Therapy Review:A Stratified Synthetic Benchmark

Background.Renoprotective therapies - SGLT2 inhibitors, finerenone, and renin-angiotensin system inhibitors (RASi) - remain underutilisedin chronic ki...

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