Eating Disorders

Development and validation of a machine learning model to predict cognitive behavioral therapy outcome in obsessive-compulsive disorder using clinical and neuroimaging data

Cognitive behavioral therapy (CBT) is a first-line treatment for obsessive-compulsive disorder (OCD), but clinical response is difficult to predict. In this study, we aimed to develop predictive models using clinical and neuroimaging data from the multicenter Enhancing Neuro-Imaging and Genetics through Meta-Analysis (ENIGMA)-OCD consortium. Baseline clinical and resting-state functional magnetic ...

PREACT-digital: Study protocol for a longitudinal, observational multi-center study on wearable- and EMA- based predictors of non-response to CBT for internalizing disorders

Despite CBT’s status as a first-line treatment, a substantial proportion of patients does not experience sufficient symptom relief. Recent advances in wearable technology and smartphone integration enable new, ecologically valid approaches to capture dynamic processes in real time. By combining ecological momentary assessment (EMA) with passive sensing of behavioral and physiological information, ...

Conversational AI in Therapy: Current Applications and Future Directions in Mental Health Support

This paper delivers a rigorous mixed-methods synthesis of conversational AI applications in mental health therapy, analyzing 47 randomized controlled ...

Signal Mining and Analysis of Adverse Events of Isotretinoin: 20-year real-world pharmacovigilance analysis based on the FAERS database

To identify post-marketing adverse event (AE) signals associated with isotretinoin using real-world data from the U.S. Food and Drug Administration (F...

Development, System Design, Safety, and Performance Metrics of a Conversational Agent for Reducing Depressive and Anxious Symptoms Based on a Large Language Model: The MHAI Study

Conversational agents based on large language models (LLMs) have shown moderate efficacy in reducing depressive and anxiety symptoms. However, most ex...

Therapy as an NLP Task: Psychologists' Comparison of LLMs and Human Peers in CBT

Wider access to therapeutic care is one of the biggest challenges in mental health treatment. Due to institutional barriers, some people seeking men...

Toward personalized care for insomnia in the US Army: a machine learning model to predict response to cognitive behavioral therapy for insomnia.

STUDY OBJECTIVES: The standard of care for military personnel with insomnia is cognitive behavioral therapy for insomnia (CBT-I). However, only a mino...

Artificial Intelligence on The Couch. Staying Human Post-AI.

This paper examines the human relationship to technology, and AI in particular, including the proposition that algorithms are the new unconscious. Key...

Using Artificial Intelligence to Identify Effective Components of Computer-Assisted Cognitive Behavioural Therapy.

Although clinician-supported computer-assisted cognitive-behaviour therapy (CCBT) is well established as an effective treatment for depression and anx...

The New Emerging Treatment Choice for Major Depressive Disorders: Digital Therapeutics.

The chapter provides an in-depth analysis of digital therapeutics (DTx) as a revolutionary approach to managing major depressive disorder (MDD). It di...

[A comparative study on treatment of lumbar degenerative disease with osteoporosis by manual and robot-assisted cortical bone trajectory screws fixation].

OBJECTIVE: To compare the safety and accuracy of manual and robot-assisted cortical bone trajectory (CBT) screws fixation in the treatment of lumbar d...

Outcomes of a Robot-Assisted Social-Emotional Understanding Intervention for Young Children with Autism Spectrum Disorders.

This study is a randomized control trial aimed at testing the role of a human-assisted social robot as an intervention mediator in a socio-emotional u...

Targeted prescription of cognitive-behavioral therapy versus person-centered counseling for depression using a machine learning approach.

OBJECTIVE: Depression is a highly common mental disorder and a major cause of disability worldwide. Several psychological interventions are available,...

Successful Treatment of Suspected Pulmonary Arterial Hypertension in a Mealy Amazon Parrot (Amazona farinose).

A 25-year-old, male mealy Amazon parrot (Amazona farinose) with a history of polycythemia, hepatomegaly, and epistaxis was evaluated for progressive l...

Diagnosis and Management of Polycythemia Vera in a Ferret ().

A 5-y-old female ferret (Mustela putorius furo) was evaluated for diarrhea, anorexia, and lethargy for 1 wk. Only mild dehydration was detected on phy...

[R0 Resection by Distal Pancreatectomy with En Bloc Celiac Axis Resection after Down-Staging by FOLFIRINOX Therapy in a Case of Pancreas Cancer--Report of a Case].

The patient, a 55-year-old man, was diagnosed elsewhere as having cancer of the tail of the pancreas and was referred to our hospital. Abdominal compu...