Emergency Medicine

Assessment of cortical bone fracture resistance curves by fusing artificial neural networks and linear regression.

Bone injures (BI) represents one of the major health problems, together with cancer and cardiovascular diseases. Assessment of the risks associated with BI is nontrivial since fragility of human cortical bone is varying with age. Due to restrictions for performing experiments on humans, only a limited number of fracture resistance curves (R-curves) for particular ages have been reported in the lit...

ir-HSP: Improved Recognition of Heat Shock Proteins, Their Families and Sub-types Based On -Spaced Di-peptide Features and Support Vector Machine.

Heat shock proteins (HSPs) play a pivotal role in cell growth and variability. Since conventional approaches are expensive and voluminous protein sequence information is available in the post-genomic era, development of an automated and accurate computational tool is highly desirable for prediction of HSPs, their families and sub-types. Thus, we propose a computational approach for reliable predic...

Assisting document triage for human kinome curation via machine learning.

In the era of data explosion, the increasing frequency of published articles presents unorthodox challenges to fulfill specific curation requirements ...

Document triage for identifying protein-protein interactions affected by mutations: a neural network ensemble approach.

The precision medicine (PM) initiative promises to identify individualized treatment depending on a patients' genetic profile and their related respon...

BioCreative VI Precision Medicine Track system performance is constrained by entity recognition and variations in corpus characteristics.

Precision medicine aims to provide personalized treatments based on individual patient profiles. One critical step towards precision medicine is lever...

Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) Associated with Mediastinal Schwannoma.

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the most common cause of euvolemic hypo-osmotic hyponatremia. There are several et...

Integrative Approach to Facilitate Fracture Healing: Topical Chinese Herbal Paste with Oral Strontium Ranelate.

Strontium ranelate (SrR) is one of the pharmaceutical agents reported to be effective on the promotion of fracture healing. This study aimed to evalua...

Refractory collapse and severe burn: Think about acute adrenal insufficiency.

INTRODUCTION: Adrenal insufficiency (AI) is a rare endocrine disorder, which can in its acute form be life-threatening in case of late diagnosis or tr...

Effect of nano-silver, nano-copper, deconex and benzalkonium chloride on biofilm formation and expression of transcription regulatory quorum sensing gene (rh1R) in drug-resistance Pseudomonas aeruginosa burn isolates.

BACKGROUND: Biofilm forming drug-resistant Pseudomonas aeruginosa are responsible for major death in burn center of different hospitals across the glo...

The distribution and redistribution of fentanyl & norfentanyl in post mortem samples.

This article compares 249 post mortem case reports that were positive for fentanyl/norfentanyl. All the cases were submitted to, and analyzed by, the ...

R-100 improves pulmonary function and systemic fluid balance in sheep with combined smoke-inhalation injury and Pseudomonas aeruginosa sepsis.

BACKGROUND: Septic shock is a major cause of death in intensive care units around the world . The aim of the study was to investigate whether the nove...

Method for the determination of Pb, Cd, Zn, Mn and Fe in rice samples using carbon nanotubes and cationic complexes of batophenanthroline.

Among cereals, rice is the second most cultivated staple crop in the world. It may be contaminated by toxic heavy metals present in water or soil. The...

Mild troponin elevation in patients admitted to the emergency department with atrial fibrillation: 30-day post-discharge prognostic significance.

Patients with atrial fibrillation (AF) often undergo troponin (Tn) testing in the emergency department (ED), but the clinical significance of mildly e...

Systemic inflammatory response syndrome, infection, and outcome in intracerebral hemorrhage.

OBJECTIVE: Systemic inflammatory response syndrome (SIRS) may be related to poor outcomes after intracerebral hemorrhage (ICH).

HHV-8-associated haemophagocytic lymphohistiocytosis in a patient with advanced AIDS.

We present a patient with advanced AIDS admitted with recurrent shock of unclear aetiology, fevers, altered mental status and refractory cytopenias. H...

Emergency department management of patients with rib fracture based on a clinical practice guideline.

BACKGROUND: Clinical practice guidelines (CPGs) have the ability to increase efficiency and standardize care. A CPG based on forced vital capacity (FV...

Bayesian averaging over Decision Tree models for trauma severity scoring.

Health care practitioners analyse possible risks of misleading decisions and need to estimate and quantify uncertainty in predictions. We have examine...

Detection of American Football Head Impacts Using Biomechanical Features and Support Vector Machine Classification.

Accumulation of head impacts may contribute to acute and long-term brain trauma. Wearable sensors can measure impact exposure, yet current sensors do ...

Prediction of Hemorrhagic Transformation Severity in Acute Stroke From Source Perfusion MRI.

OBJECTIVE: Hemorrhagic transformation (HT) is the most severe complication of reperfusion therapy in acute ischemic stroke (AIS) patients. Management ...

Communication with Orthopedic Trauma Patients via an Automated Mobile Phone Messaging Robot.

BACKGROUND: Communication with orthopedic trauma patients is traditionally problematic with low response rates (RRs). The purpose of this investigatio...