Endocrinology

Latest AI and machine learning research in endocrinology for healthcare professionals.

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Development of Insulin Bolus Calculators in Type 1 Diabetes Using a Framework Based on Real-World Data, Digital Twins and Machine Learning.

OBJECTIVE: Precise mealtime insulin bolus (MIB) dosing is essential in type 1 diabetes (T1D) to minimize glucose excursions from carbohydrate intake. Traditional MIB formulas, based on glucose concentration at mealtime, are suboptimal and do not exploit real-time data from continuous glucose monitoring (CGM). Existing methods that incorporate CGM data often rely on empirical rules or are developed...

Sep 1 2026 41447489

Applications of Deep Learning in Endocrine Neoplasms.

Machine learning methods have been growing in prominence across all areas of medicine. In pathology, recent advances in deep learning (DL) have enabled computational analysis of histological samples, aiding in diagnosis and characterization in multiple disease areas. In cancer, and particularly endocrine cancer, DL approaches have been shown to be useful in tasks ranging from tumor grading to gene...

Sep 1 2026 42526978
Development of a Prognostic Survival Risk Score for Lung Cancer Patients With Type 2 Diabetes Mellitus: A Territory-Wide Retrospective Cohort Study.

BACKGROUND: Lung cancer is a leading cause of cancer-related mortality, and its prognosis is often affected by comorbidities such as type 2 diabetes m...

Sep 1 2026 42655935
Artificial Intelligence-Estimated Intrapancreatic Fat and Its Relationship to Familial and Germline Pancreatic Cancer Risk.

BACKGROUND: Family history of pancreatic cancer (PC), pathogenic germline variants (PGVs), and increased intrapancreatic fat (IPF) are individually as...

Sep 1 2026 42666046
AI-Assisted Sonography for the Diagnosis of Thyroid Nodules.

PURPOSE: To evaluate the diagnostic accuracy, clinical utility, and workflow integration of artificial intelligence (AI)-assisted sonography for the a...

Sep 1 2026 42671965
Mechanistic and Clinical Perspectives on Traditional Chinese Medicine in Thyroid Cancer Management.

Thyroid cancer is one of the most prevalent malignancies of the endocrine system, comprising various subtypes such as papillary thyroid carcinoma (PTC...

Aug 31 2026 42676033
A Textile-Based, Battery-Free, Electrochromic Platform for Visual Epidermal Sweat Biosensing.

Noninvasive wearable sweat sensors are promising for personalized health management, yet their widespread adoption is hindered by complex multi-compon...

Aug 31 2026 42671390
Graph attention-guided multi-modal learning for high-throughput screening of environmental chemicals associated with breast cancer risk.

The rapid expansion of chemical production and use has increased human exposure to environmental chemicals that can impact biological pathways relevan...

Aug 31 2026 42674177
Identification of comorbidity-based clusters and mortality risk in hospitalised patients with diabetes mellitus in Karachi, Pakistan: a machine learning analysis.

BACKGROUND: Diabetes has reached epidemic proportions in Pakistan. This study applied machine learning (ML) techniques to identify comorbidity-based a...

Aug 31 2026 42674787
Retrospective population-based cohorts for assessing the performance of algorithmic diabetes classification and for quantifying the true burden of type 1, type 2 and LADA phenotypes in Quebec: a study protocol.

INTRODUCTION: Diabetes affects 537 million people worldwide, with type 2 diabetes (T2D) estimated to account for most cases. Type 1 diabetes (T1D), la...

Aug 31 2026 42674789
Bump2Baby & Me+ (B2B&Me+): Protocol for a multi-country, European hybrid type 3 implementation-effectiveness study to reduce the incidence of gestational diabetes mellitus and improve maternal and child health.

BACKGROUND: Gestational diabetes mellitus (GDM) affects 1-in-7 pregnancies globally and is associated with significant short- and long-term health con...

Aug 31 2026 42672070
Glucose-to-albumin ratio and mortality in ICU patients with acute pancreatitis.

OBJECTIVES: Acute pancreatitis (AP) carries a high mortality risk in ICU patients. The glucose-to-albumin ratio (GAR), reflecting metabolic stress and...

Aug 31 2026 42666811
Parkinson's Disease and Retinal Age Gap: A Cross-Sectional Analysis.

BACKGROUND: Deep-learning models are capable of predicting age from retinal scans and the difference between this and chronological age, retinal age g...

Aug 30 2026 42670076
Vaginal drug delivery for precision therapy in polyendocrine metabolic ovarian syndrome: emerging technologies, translational challenges and future perspectives.

INTRODUCTION: Polyendocrine Metabolic Ovarian Syndrome (PMOS) is an endocrine disorder characterized by metabolic dysfunction, hormonal imbalance, inf...

Aug 30 2026 42670175
Multi-omics, machine learning, and molecular simulation identify CD44 as a candidate target in endocrine-disrupting chemical-associated thyroid cancer progression.

Endocrine-disrupting chemicals (EDCs) are widely present in the environment and consumer products and may disturb thyroid hormone homeostasis. However...

Aug 30 2026 42669107
Clinical and Metabolomic Panel for Noninvasive Screening of Biopsy-Confirmed MASH in Children and Adolescents.

BACKGROUND & AIMS: Noninvasive tests to identify pediatric metabolic dysfunction-associated steatohepatitis (MASH) remain a critical need. We aimed to...

Aug 30 2026 42669329
Non-Oncology Biomarkers in Precision Medicine: A Narrative Review.

Precision medicine has revolutionized oncology by leveraging biomarkers for individualized therapy selection, early diagnosis, and real-time disease m...

Aug 29 2026 42667586
Integrative single-cell and spatial transcriptomic analysis reveals 4-HNE-related stromal remodeling in lung adenocarcinoma.

BACKGROUND: 4-HNE is a lipid peroxidation product involved in oxidative stress, tumor microenvironment remodeling, and tumor progression. This study a...

Aug 29 2026 42667808
Application of Artificial Intelligence in Diagnosis and Management of Thyroid Disease.

Artificial intelligence (AI) is transforming thyroid care, with applications spanning ultrasound risk stratification, cytopathology, histopathology, r...

Aug 29 2026 42667959
Pooled two-cohort MRI body composition phenotyping with open-source deep learning.

BACKGROUND: Body mass index fails to capture variation in fat and muscle distribution that determines metabolic health and disease risk. MRI enables r...

Aug 29 2026 42668286
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