Endocrinology

Combined Effect of Low-Level Laser Treatment and Levothyroxine on Wound Healing in Rats With Hypothyroidism.

Hypothyroidism delays wound healing by reducing the synthesis of keratinocytes, fibroblast cells, and collagen. Methods for enhancement of wound healing include laser therapy and hormone therapy. The current study evaluated the combined effect of laser and levothyroxine therapy to cure wounds in male rats with hypothyroidism. Sixty male Wistar rats were randomly divided into 5 groups: (1) health...

Triglycerides and glucose index as an insulin resistance marker in a sample of healthy adults.

AIM: To assess the association between elevated triglycerides/glucose index (TGI) and insulin resistance (IR) or hyperinsulinemia after oral glucose tolerance test (OGTT) in a sample of healthy adults.

Feature Selection and Parameters Optimization of Support Vector Machines Based on Hybrid Glowworm Swarm Optimization for Classification of Diabetic Retinopathy.

Diabetic Retinopathy (DR) has been a leading cause of blindness in case of human beings falling between the ages of 20 and 74 years. This will have a ...

Association between vitamin D deficiency and insulin resistance markers in euthyroid non-diabetic individuals.

AIM: To evaluate the association between vitamin D deficiency and insulin resistance (IR) or hyperinsulinemia after oral glucose tolerance test (OGTT)...

Evaluation of Artificial Intelligence-Based Grading of Diabetic Retinopathy in Primary Care.

IMPORTANCE: There has been wide interest in using artificial intelligence (AI)-based grading of retinal images to identify diabetic retinopathy, but s...

Fibroblast growth factor23 is associated with axonal integrity and neural network architecture in the human frontal lobes.

Elevated levels of FGF23 in individuals with chronic kidney disease (CKD) are associated with adverse health outcomes, such as increased mortality, la...

Digital Diabetes Data and Artificial Intelligence: A Time for Humility Not Hubris.

In the future artificial intelligence (AI) will have the potential to improve outcomes diabetes care. With the creation of new sensors for physiologic...

Effect of deglutition aids on the inhibitory effect of orally disintegrating tablets of voglibose on the postprandial elevation of blood glucose levels: a case investigating the interaction between xanthan gum and voglibose.

In this study, we first performed a disintegration test of the voglibose orally disintegrating (V-OD) tablet immersed in jelly-wafer (JW, V-ODims/jw) ...

Mixed effect machine learning: A framework for predicting longitudinal change in hemoglobin A1c.

Accurate and reliable prediction of clinical progression over time has the potential to improve the outcomes of chronic disease. The classical approac...

Machine learning identifies interacting genetic variants contributing to breast cancer risk: A case study in Finnish cases and controls.

We propose an effective machine learning approach to identify group of interacting single nucleotide polymorphisms (SNPs), which contribute most to th...

Remote-access thyroid surgery-progress, assessment, and reflection.

The usefulness of fine-needle aspirates for detection of recurrent carcinoma in the thyroid bed.

INTRODUCTION: Locoregional recurrence of thyroid carcinoma has a negative impact on patient prognosis. In the current study, we retrospectively review...

Identifying people at risk of developing type 2 diabetes: A comparison of predictive analytics techniques and predictor variables.

BACKGROUND: The present study aims to identify the patients at risk of type 2 diabetes (T2D). There is a body of literature that uses machine learning...

Comparing Multiple Machine Learning Algorithms and Metrics for Estrogen Receptor Binding Prediction.

Many chemicals that disrupt endocrine function have been linked to a variety of adverse biological outcomes. However, screening for endocrine disrupti...

Computational characterization and identification of human polycystic ovary syndrome genes.

Human polycystic ovary syndrome (PCOS) is a highly heritable disease regulated by genetic and environmental factors. Identifying PCOS genes is time co...

Pivotal trial of an autonomous AI-based diagnostic system for detection of diabetic retinopathy in primary care offices.

Artificial Intelligence (AI) has long promised to increase healthcare affordability, quality and accessibility but FDA, until recently, had never auth...

Predictors of atrial fibrillation early recurrence following cryoballoon ablation of pulmonary veins using statistical assessment and machine learning algorithms.

Inflammation, oxidative stress, myocardial injury biomarkers and clinical parameters (longer AF duration, left atrial enlargement, the metabolic syndr...

Convolutional Neural Network Using a Breast MRI Tumor Dataset Can Predict Oncotype Dx Recurrence Score.

BACKGROUND: Oncotype Dx is a validated genetic analysis that provides a recurrence score (RS) to quantitatively predict outcomes in patients who meet ...

Low Protein Z Level: A Thrombophilic Risk Biomarker for Acute Coronary Syndrome.

Acute coronary syndrome (ACS) encompasses a range of thrombotic coronary artery diseases. Protein Z (PZ)/PZ-dependent protease inhibitor complex is a ...

Using Machine Learning to Aid the Interpretation of Urine Steroid Profiles.

BACKGROUND: Urine steroid profiles are used in clinical practice for the diagnosis and monitoring of disorders of steroidogenesis and adrenal patholog...