Endocrinology

Machine learning reveals sex-specific 17β-estradiol-responsive expression patterns in white perch (Morone americana) plasma proteins.

With growing abundance and awareness of endocrine disrupting compounds (EDCs) in the environment, there is a need for accurate and reliable detection of EDC exposure. Our objective in the present study was to observe differences within and between the global plasma proteomes of sexually mature male and female white perch (Morone americana) before (Initial Control, IC) and after 17β-estradiol (E2 )...

Does preoperative diabetes mellitus affect weight loss outcome after biliopancreatic diversion with duodenal switch?

BACKGROUND: Preoperative type 2 diabetes mellitus (T2 DM) has previously been reported as an independent predictor for suboptimal (≤40%) weight loss after Roux-en-Y gastric bypass in patients with T2 DM compared with patients who do not have T2 DM. This association has not been shown to apply to patients who undergo biliopancreatic diversion with duodenal switch (BPD/DS). BPD/DS is currently the m...

Population pharmacokinetic/pharmacodynamic assessment of pharmacological effect of a selective estrogen receptor β agonist on total testosterone in healthy men.

BACKGROUND: LY500307 is a highly selective estrogen receptor β (ERβ) agonist, which loses its selectivity at high dose and leads to undesirable suppre...

Comparative assessment of glucose prediction models for patients with type 1 diabetes mellitus applying sensors for glucose and physical activity monitoring.

The present work presents the comparative assessment of four glucose prediction models for patients with type 1 diabetes mellitus (T1DM) using data fr...

Lack of association between anemia and renal disease progression in Chinese patients with type 2 diabetes.

AIMS/INTRODUCTION: Anemia has a close interaction with renal dysfunction in diabetes patients. More proof is still awaited on the relationship between...

Effects of xenoestrogens in human M1 and M2 macrophage migration, cytokine release, and estrogen-related signaling pathways.

Bisphenol A (BPA), bis(2-ethylhexyl)phthalate (DEHP) and di(n-butyl)phthalate (DBP) are environmental estrogens that have been associated with a wide ...

Transoral robotic excision of ectopic lingual thyroid: Case series and literature review.

BACKGROUND: Surgical excision of an ectopic lingual thyroid has traditionally been associated with significant morbidity and has therefore been reserv...

Robotic thyroidectomy versus conventional open thyroidectomy for differentiated thyroid cancer: meta-analysis.

OBJECTIVE: To conduct a meta-analysis to compare the short-term outcomes of robotic thyroidectomy and conventional open thyroidectomy for differentiat...

Robot-assisted transaxillary thyroidectomy: surgical technique.

Robot-assisted transaxillary thyroid surgery avoids the need for a neck incision. It consists of thyroid lobectomy and isthmectomy for moderately larg...

Anatomical features of skull base and oral cavity: a pilot study to determine the accessibility of the sella by transoral robotic-assisted surgery.

The role of transoral robotic surgery (TORS) in the skull base emerges and represents the natural progression toward miniinvasive resections in confin...

Applying a novel combination of techniques to develop a predictive model for diabetes complications.

Among the many related issues of diabetes management, its complications constitute the main part of the heavy burden of this disease. The aim of this ...

Trans-oral robotic surgery and surgeon-performed trans-oral ultrasound for intraoperative location and excision of an isolated retropharyngeal lymph node metastasis of papillary thyroid carcinoma.

BACKGROUND: Retropharyngeal metastases are uncommon but a well-known location for regional spread of well-differentiated thyroid carcinoma (WDTC). Sur...

Transaxillary thyroidectomies: a comparative learning experience of robotic vs endoscopic thyroidectomies.

OBJECTIVE: Robotic and endoscopic approaches have become more accepted in thyroid surgery, with current literature documenting the experience of high-...

Diagnosis of Malignancy in Thyroid Tumors by Multi-Layer Perceptron Neural Networks With Different Batch Learning Algorithms.

To diagnose the malignancy in thyroid tumor, neural network approach is applied and the performances of thirteen batch learning algorithms are investi...

Spectrum and Prevalence of Thyroid Disorders in Patients Admitted to the Anaesthesiology Outpatient Clinic for Surgery.

OBJECTIVE: An anaesthetic approach and surgery are important treatment strategies in patients with thyroid dysfunction due to potential complications....

Development of an antidiabetic formulation (ADJ6) and its inhibitory activity against α-amylase and α-glucosidase.

There has recently been much advancement in the diagnosis, treatment, and research of metabolic disorders, especially diabetes. Current research aroun...

Investigation of Effects of Epidural Anaesthesia Combined with General Anaesthesia on the Stress Response in Patients Undergoing Hip and Knee Arthroplasty.

OBJECTIVE: To investigate the effects of general anaesthesia and general+epidural anaesthesia on the stress response which was evaluated with the adre...

Identification of Type 2 Diabetes Risk Factors Using Phenotypes Consisting of Anthropometry and Triglycerides based on Machine Learning.

The hypertriglyceridemic waist (HW) phenotype is strongly associated with type 2 diabetes; however, to date, no study has assessed the predictive powe...

Surgical safety and oncologic effectiveness in robotic versus conventional open thyroidectomy in thyroid cancer: a systematic review and meta-analysis.

BACKGROUND: Although many experiences using the da Vinci Robot System have been reported by several groups, there is substantial controversy over the ...

Diabetes knowledge in young adults: associations with hemoglobin A1C.

The purpose of this study was to quantify associations between hemoglobin A1C (A1C) and diabetes knowledge score using an assessment tool developed to...