Endocrinology

Latest AI and machine learning research in endocrinology for healthcare professionals.

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Bump2Baby & Me+ (B2B&Me+): Protocol for a multi-country, European implementation project to reduce the incidence of gestational diabetes mellitus and improve maternal and child health

Background Gestational diabetes mellitus (GDM) affects 1-in-7 pregnancies globally and is associated with significant short- and long-term health consequences. Although health behaviour change interventions can effectively reduce these risks, a significant implementation gap exists in translating this evidence into routine practice. Bump2Baby and Me (B2B&Me) was a mobile health (mHealth) coaching ...

Autonomous computational prioritisation of colorectal cancer vulnerabilities via multi-scale AI swarms

The acceleration of automated scientific discovery has been fundamentally bottlenecked by the epistemic gap between the semantic reasoning of large language models (LLMs) and the complex, non-linear reality of mammalian biology. While recent multi-agent frameworks have achieved autonomous hypothesis generation and in vitro experimental analysis, they frequently lack the rigorous statistical constr...

Association between glycated hemoglobin A1c and automated abdominal aortic calcification: the UK Biobank Imaging Study

Background: Poor glycemic control is associated with cardiovascular disease (CVD) risk. However, it is unknown whether glycemic control is related to ...

Reinforcement Learning for Chronic Care Pathway Optimization: A Unified Framework across Three Clinical Goal Types

Objective: Chronic care requires sequential treatment under competing biomarker, safety, and cost constraints, yet clinical goal structures differ acr...

Causal-RetiGraph: Cross-Cohort Retinal Support and Same-Subject Pathway Analysis for Diabetic Retinopathy

Diabetic retinopathy (DR) is a local retinal lesion process and a visible manifestation of systemic microvascular injury. Modern retinal AI can grade ...

Jul 6 2026 2607.05204v1
Combined triglyceride-glucose and frailty index (TyGFI) and risk of endometrial cancer in U.S. women aged >=45: NHANES 2011-2018 analysis integrating data engineering and machine learning with logistic modeling

Endometrial cancer (EC) incidence is closely linked to metabolic and hormonal factors. The TyGFI, a composite indicator integrating the triglyceride-g...

A foundation model of wearable pulse oximetry reveals physiological signatures of health and cardiometabolic risk

While Photoplethysmography (PPG) is established as a noninvasive optical tool for monitoring heart rate and oxygen saturation, its high-resolution blo...

Population-Scale Segmentation of Penile Tissue in DIXON MRI using Deep Learning for Quantitative Phenotyping in Male Reproductive Health

Penile measurement is clinically relevant across male reproductive and urogenital health, including conditions such as micropenis, congenital and endo...

Jul 2 2026 2607.02127v1
MedSaab-US: A Backpropagation-Free Multi-Scale Wavelet-Saab Framework for Thyroid Nodule Segmentation in Ultrasound Images

Deep learning (DL) methods dominate thyroid nodule segmentation in ultrasound (US) images, achieving high Dice scores but at the cost of millions of p...

Jul 2 2026 2607.02209v1
Nutrient-dependent hippocampus dopamine signaling enhances meal-related episodic memory and reduces food intake

Background: Dopamine (DA) is a neurotransmitter critically involved in food-related reinforcement learning. While mesolimbic DA reward-associated sign...

Decoding the regulatory genetic architecture of endometriosis using AlphaGenome

Background Endometriosis is a complex, estrogen-dependent disease with a strong genetic component. Although genome-wide association studies (GWAS) hav...

Accelerometry-Derived Digital Biomarkers for Cardiometabolic Risk: A Population-Representative Tabular Benchmark with Uncertainty Quantification

Structured tabular data dominates clinical medicine, yet existing benchmarks fail to reflect real-world properties like complex survey sampling, demog...

Jun 29 2026 2606.30702v1
Integrating dynamic nomogram and machine learning for personalized disability prediction in elderly cardiometabolic multimorbidity: routine blood markers and mental health

Abstract Background: Disability prediction in elderly with cardiometabolic multimorbidity (CMM) is limited. We developed a dynamic nomogram and addres...

Interventional Flow Matching: Prospective Dose-Response Forecasting with Velocity-Field Jacobian Regularization

Predicting a patient's physiological trajectory under a planned treatment sequence is a prospective interventional problem, not standard time-series e...

Jun 28 2026 2606.29386v1
Response consistency of ChatGPT-4o for Type 2 Diabetes Nutrition and Physical-activity Recommendations: A Pilot NLP-based Assessment of GPT outputs

Generative AI tools such as ChatGPT are increasingly used by the public to seek guidance on diet and physical activity for type 2 diabetes (T2D) preve...

An Agentic, No Code Artificial Intelligence Workflow for Developing and Externally Validating a Thyroid Nodule Ultrasound Malignancy Classifier

Convolutional neural networks (CNNs) can classify thyroid nodules on ultrasound, yet published models are seldom available for independent testing, re...

Predicting county-level diagnosed diabetes prevalence in the United States using explainable gradient boosting and geographic interpretation

Diagnosed diabetes affects approximately 38.4 million Americans, but its burden is not evenly distributed across U.S. counties. Existing machine-learn...

Trait anxiety drives premature disengagement despite intact opportunity-cost sensitivity

Anxiety has been linked to difficulty sustaining engagement with ongoing tasks, even when continued engagement would yield greater rewards, yet the un...

A Dual Edge Spatial Jacobian Image Graph for Interpretable Diabetic Retinopathy Grading

Automated diabetic retinopathy (DR) grading from colour fundus photographs can achieve strong predictive performance, but clinical interpretation requ...

Jun 23 2026 2606.24168v1
Machine learning-based modeling to predict inhibitors for targets of Alzheimer's Disease

Alzheimer's Disease is a chronic neurodegenerative disorder projected to affect 115 million people by 2050, driven by mechanisms like the cholinergic ...

Jun 23 2026 2606.24372v1
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