Endocrinology

Latest AI and machine learning research in endocrinology for healthcare professionals.

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Showing 3741-3760 of 7,676 articles

Cumulative Metabolic Exposure to Hyperglycemia and Risk of Cardiovascular and Limb Events in Peripheral Artery Disease

Background: Although diabetes is a potent risk factor for the development of peripheral artery disease (PAD), the effect of cumulative metabolic exposure to hyperglycemia on risk of cardiovascular or limb events in patients with PAD remains unclear. Methods: The Peripheral Artery Disease: Long-term Survival (PEARLS) is a longitudinal registry of Veterans with newly diagnosed PAD identified using a...

How does AI detect diabetic retinopathy from retinal photos? A heatmap analysis of 54 deep learning models

Purpose: To investigate how artificial intelligence (AI) systems detect referrable diabetic retinopathy (DR) from retinal photographs by analysing heatmap patterns and determining their overlap with DR features. Methods: Fifty-four AI systems were developed using 27 backbone architectures, with each implemented as both binary-referable and multi-class grading models based on the International Clin...

Body composition subphenotypes, cardiometabolic risk and incident outcomes: validation in the population-based NAKO and UK Biobank imaging cohorts

Background Anthropometric measures do not adequately capture heterogeneity in body fat distribution and corresponding cardiometabolic risk, whereas ma...

Insulin4RL: Real-Time Insulin Management in the Intensive Care Unit for Offline Reinforcement Learning

Offline reinforcement learning (ORL) offers the potential to improve the quality of clinical decision-making using historical electronic health record...

Jun 17 2026 2606.19481v1
Predicting Mouse Lifespan-Extending Chemical Compounds with Machine Learning

Pharmacological interventions targeting the biological processes of ageing hold significant potential to extend healthspan and promote longevity. This...

MetaboNet-Bench: A Multi-modal Benchmark for Glucose Forecasting in Type 1 Diabetes

Glucose forecasting algorithms are an important aspect of glycemic control management in type 1 diabetes. So far, the research community has developed...

Jun 17 2026 2606.18640v1
Context-Aware Optimization of Follow-Up Intervals for Type 2 Diabetes Care Using Markov Decision Processes

Chronic disease management relies on regular patient-provider interactions to follow-up on disease progression and control. For Type 2 Diabetes (T2D),...

Jun 17 2026 2606.19092v1
Beyond the Blood Draw: Explainable Machine Learning for Non-Invasive Dysglycemia Risk Screening

Dysglycemia, encompassing both prediabetes and diabetes, affects huge numbers of adults worldwide, yet many of them remain undiagnosed. We developed a...

Jun 14 2026 2606.16056v1
Order-Based Bayesian Network Modeling of Early Detection and Post-Diagnosis Control for Cardiovascular Disease Risk in Type 2 Diabetes

Patients diagnosed with type 2 diabetes (T2D) are at increased risk of developing cardiovascular disease (CVD), the leading cause of morbidity and mor...

Computer Vision for Real-Time Anatomical Navigation in Neurosurgery: First-in-Human Clinical Evaluation and Iterative Development (IDEAL Stage 1)

Introduction: Precise anatomical navigation is fundamental to safe endoscopic pituitary surgery, a high-stakes procedure characterised by a challengin...

LLM-Powered Personalized Glycemic Assessment in Type 2 Diabetes with Wearable Sensor Data

Type 2 Diabetes (T2D) poses an increasing global health threat, demanding effective glycemic assessment to support personalized and improved diabetes ...

Jun 10 2026 2606.12699v1
Transcriptomic Architecture of Type 2 Diabetes in Human Pancreatic Islets:An Integrative Meta-Analysis and Machine Learning Framework for Biomarker Discovery

Background. Type 2 diabetes mellitus (T2D) is defined by progressive pancreatic {beta}-cell dysfunction whose molecular underpinnings remain incomplet...

Optimisation of steatotic liver disease screening algorithm for resource-poor settings using machine learning

Background The European Association for the Study of the Liver (ESAL) - Steatotic Liver Disease (SLD) screening algorithm involves two steps; initial ...

Seeing Below the Limit of Detection: A Censored-Poisson Bayesian Latent-Growth Change-Point Detector (the Span Detector) for Serial ctDNA in HR+/HER2- Metastatic Breast Cancer

Circulating-tumour DNA (ctDNA) carries evidence of drug resistance months before imaging shows it, but the earliest evidence lives below the assay's l...

Jun 10 2026 2606.11876v1
Multimodal Brain Tumour Classification Using Feature Fusion

Clinicians diagnose brain tumors by synthesizing patient symptoms, medical history, and quantitative imaging data from modalities such as MRI and CT s...

Jun 9 2026 2606.11107v2
Real-world safety profile of Enfortumab Vedotin: A comprehensive pharmacovigilance analysis based on the FDA Adverse Event Reporting System (FAERS)

Background: This study aimed to evaluate real-world adverse event (AE) signals of EV to provide evidence-based guidance for its safe clinical applicat...

AI-guided analysis of human pancreatic islet sociology reveals distinct cell compositional changes in type 1 diabetes

Human pancreatic islets exhibit greater anatomic and cellular heterogeneity than previously appreciated, raising fundamental questions about how their...

Multimodal Brain Tumour Classification Using Feature Fusion

Clinicians diagnose brain tumors by synthesizing patient symptoms, medical history, and quantitative imaging data from modalities such as MRI and CT s...

Jun 9 2026 2606.11107v1
MetaPlate: Counterfactual-Guided RAG-LLM Tool for Personalized Food Recommendation and Hyperglycemia Prevention

Postprandial hyperglycemia is a key risk factor for metabolic disorders; however, existing dietary guidance is often static, impractical, and insuffic...

Jun 8 2026 2606.10120v1
A hierarchical clinical fusion transformer model for personalized opioid treatment: Development and validation in diabetic surgical patients

Background Machine learning (ML) models are increasingly used to predict adverse outcomes after surgery. However, most rely on static patient characte...

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