Endocrinology

Latest AI and machine learning research in endocrinology for healthcare professionals.

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The use of machine learning to predict pharmacological therapy in gestational diabetes: A scoping review.

AIMS: Early identification of pharmacological therapy for gestational diabetes mellitus (GDM), a common pregnancy complication, through machine learning could allow for better therapeutic strategies and improved treatment efficiency. This scoping review aimed to comprehensively review the machine learning models used to predict the need for pharmacological therapy in GDM. METHODS: Four electronic ...

Nov 18 2025 41254474

Interpretable Machine Learning Model for Survival Prediction in Pediatric Adrenocortical Tumors.

PURPOSE: Pediatric adrenocortical tumors (pACTs) are rare and clinically heterogeneous. Existing risk stratification systems rely on fixed thresholds and linear assumptions, which may limit their prognostic accuracy-particularly for nonmetastatic, locally advanced cases. We aimed to develop an interpretable machine learning (ML) model for individualized survival prediction using only routine clini...

Nov 18 2025 41608202
Diverse combination of factors associated with the development of diabetic kidney disease among data-driven diabetes subtypes: analysis of the J-DREAMS registry.

AIMS/HYPOTHESIS: Available methods for predicting the onset and progression of diabetic kidney disease (DKD) and end-stage kidney disease (ESKD) are n...

Nov 17 2025 41247492
Artificial intelligence-driven clinical decision support systems to assist healthcare professionals and people with diabetes in Europe at the point of care: a Delphi-based consensus roadmap.

The use of artificial intelligence (AI) to improve the diagnosis, assessment and treatment of people with diabetes has the potential to drive a paradi...

Nov 17 2025 41247494
A Novel Instance Segmentation Method for Real-Time Detection of Thyroid Nodules in Ultrasound Videos: A Multi-Center Study.

OBJECTIVES: Thyroid nodules are one of the most common thyroid disorders and can be categorized into benign and malignant thyroid nodules. Currently, ...

Nov 17 2025 41253629
Streamlining the Histopathologic Workflow in Diabetic Kidney Disease with Artificial Intelligence.

KEY POINTS: Artificial intelligence models effectively generalized across studies and animal models and reduced translational gaps when applied to hum...

Nov 12 2025 41222991
Manipulating starch crystalline structure for controlled digestibility and glycemic response.

Postprandial hyperglycemia is a key driver in the development of type 2 diabetes, and dietary starch is a major modulator of glycemic response. The cr...

Nov 12 2025 41320420
Association of HbA1c and an updated glucose management indicator (uGMI) with incident diabetic retinopathy in adults with type 1 diabetes: a longitudinal study.

AIMS/HYPOTHESIS: This study aimed to compare the predictive performance of HbA1c and a continuous glucose monitoring (CGM)-based updated glucose manag...

Nov 11 2025 41217525
Noninvasive follicular thyroid neoplasm with papillary-like nuclear features: an update.

PURPOSE OF REVIEW: Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) has been recognized as a diagnostic entity sin...

Nov 10 2025 41213591
Artificial intelligence in nephrology: predicting CKD progression and personalizing treatment.

Chronic kidney disease (CKD) represents a major and expanding global health challenge, with prevalence rising due to aging populations, diabetes, hype...

Nov 8 2025 41205136
The Development and Validation of Multivariable Electronic Health Record-Based Models to Predict Diabetic Ketoacidosis-Related Hospitalizations for Adults with Type 1 Diabetes.

AIM: To develop and validate models that use electronic health record (EHR) data to predict diabetic ketoacidosis (DKA)-related hospitalizations over ...

Nov 7 2025 41556335
Mapping systemic inter-organ metabolic networks across glycemic continuum using whole-body [18F]FDG PET/CT and machine learning.

PURPOSE: Glucose homeostasis relies on coordinated interactions among multiple organs, and its disruption relates to diabetes development. This study ...

Nov 7 2025 41198990
The application of machine learning in the evaluation of urinary tract infections incidence in patients in a Nursing and Treatment Facility.

BACKGROUND: Urinary tract infection (UTI) is a serious problem in the healthcare system. It is caused by bacteria from the gastrointestinal tract. The...

Nov 7 2025 41199126
Can artificial intelligence and wearable technologies transform diabetes foot health?

PURPOSE OF REVIEW: Diabetes foot ulcers (DFUs) affect millions globally, and are a global health challenge, contributing significantly to morbidity, m...

Nov 6 2025 41314635
A multi-task deep learning framework for intraoperative diagnosis of thyroid cancer metastasis using whole slide images.

BACKGROUND: Lymph node metastasis (LNM) is a critical prognostic indicator in papillary thyroid carcinoma (PTC), significantly influencing surgical de...

Nov 4 2025 41237514
Demonstrating the potential of untargeted hair proteomics for personalized biomarkers in stress-associated disorders.

Biomarker research in psychopathology increasingly employs high-dimensional Omics approaches. Yet, proteomics based on human hair remain largely unexp...

Nov 4 2025 41275754
Microbiome based precision medicine through integrated multiomics and machine learning.

Gut microbiome (GME) is a dynamic ecosystem composed of diverse microorganisms with extensive functional potential that influence host physiology, end...

Nov 3 2025 41192043
Assessing the User Experience of an LLM-Based Conversational Assistant in Diabetes Mellitus Care.

UNLABELLED: This article presents the design, implementation, and evaluation of MarIA, a GPT-3.5-powered virtual assistant integrated into a messaging...

Nov 1 2025 41658406
Unraveling Shared Diagnostic Biomarkers: Integrated Bioinformatics Identification of CGB7, MYCNUT, and GPR32 in Gestational Diabetes Mellitus and Retinopathy of Prematurity.

The relationship between Gestational Diabetes Mellitus (GDM) and Retinopathy of Prematurity (ROP) is not fully understood, but both conditions may sha...

Oct 30 2025 41161773
Takotsubo cardiomyopathy: Advances in pathophysiology, diagnostic biomarkers, genetic insights, multisystemic involvement, treatment updates & multidisciplinary interventions.

BACKGROUND: Takotsubo cardiomyopathy (TTC) is an acute, reversible cardiac syndrome triggered by physical or emotional stress, involving complex multi...

Oct 30 2025 41173762
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