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Exercise & Fitness

Latest AI and machine learning research in exercise & fitness for healthcare professionals.

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Focused ultrasound neuromodulation of mediodorsal thalamus disrupts decision flexibility during reward learning

When learning to find the most beneficial course of action, the prefrontal cortex guides decisions by comparing estimates of the relative value of the options available. Basic neuroscience studies in animals support the view that the thalamus can regulate the activity within and across the prefrontal cortex. However, it is unknown if it can modify value-based decision making in humans. Understandi...

MeFEm: Medical Face Embedding model

We present MeFEm, a vision model based on a modified Joint Embedding Predictive Architecture (JEPA) for biometric and medical analysis from facial images. Key modifications include an axial stripe masking strategy to focus learning on semantically relevant regions, a circular loss weighting scheme, and the probabilistic reassignment of the CLS token for high quality linear probing. Trained on a co...

Feb 16 2026 2602.14672v1
Genomics link obesity and type 2 diabetes to Alzheimer's disease to unveil novel biological insights

Body mass index (BMI), type 2 diabetes (T2D) and associated cardiometabolic features modify Alzheimer's disease (AD) risk, yet shared mechanisms remai...

Likelihood-based fine-tuning of protein language models for few-shot fitness prediction and design

Machine learning models trained on measurements of protein functional properties are widely used to accelerate laboratory-based protein design campaig...

Neuroscience-Inspired Deep Learning Brain-Machine Interface Decoder

Brain machine interfaces (BMIs) aim to decode motor intentions from neural activity to enable direct control of external devices. However, most existi...

Distributional Impacts of AI-Enhanced Telerehabilitation on Functional Recovery: A Recentered Influence Function Quantile Regression Decomposition Analysis

Background: Conventional evaluations of digital health interventions typically assess mean treatment effects, potentially masking heterogeneous impact...

Machine Learning Phenotyping of Autonomic Stress from Daily Temperature and Ecological Assessments

Background: Artificial intelligence applications for preventive stress monitoring remain limited by dependence on expensive continuous biosensors. We ...

UniFacePoint-FM: A Foundation Model for Generalizable 3D Facial Representation Learning and Multi-Attribute Prediction

The human face is a rich medium for biometric, behavioral, and clinical information. However, 2D facial images based technologies lack critical geomet...

Explainable Machine Learning Framework for Predicting Cardiometabolic Risk Using Meal Timing and Eating Habits

Background- Eating timing and regularity represent new contributors to metabolic health, however, the time-based aspect of eating behavior is rarely i...

An AI-Native Biofoundry for Autonomous Enzyme Engineering: Integrating Active Learning with Automated Experimentation

The engineering of enzymes with novel functions is a cornerstone of synthetic biology but remains bottlenecked by the fragmentation between computatio...

Targeted saliva multi-omics is a reliable, non-invasive method to capture physiological stress and recovery

Determining physiological stress at high resolution is crucial across diverse settings to enable informed decision-making in the context of health and...

Machine Learning Identifies Distinct Treg-Mediated Remodeling in HFpEF Hearts Treated with Neonatal Mesenchymal Stem Cells and Their Secretome

Background: Heart failure with preserved ejection fraction (HFpEF) remains a major therapeutic challenge due to its complex pathophysiology and pronou...

Multi-omic deep learning identifies exercise-responsive ageing pathways in humans

Genome-wide association studies of physical activity traits have mapped numerous loci, yet the molecular mechanisms through which exercise influences ...

Electrophysiological Correlates of Reinforcement Learning in the Human Ventral Tegmental Area

The ventral tegmental area is the primary source of dopaminergic input to the human prefrontal cortex and plays a central role in reinforcement learni...

Masked Depth Modeling for Spatial Perception

Spatial visual perception is a fundamental requirement in physical-world applications like autonomous driving and robotic manipulation, driven by the ...

Jan 25 2026 2601.17895v1
TOSHFA: A Mobile VR-Based System for Pose-Guided Exercise Rehabilitation for Low Back Pain

Low back pain (LBP) is a pervasive global health challenge, affecting approximately 80% of adults and frequently progressing into chronic or recurrent...

Jan 24 2026 2601.17553v1
Hybrid rule-based and on-premises LLM pipeline for extracting CMR and CPET metrics from free-text reports in repaired tetralogy of Fallot

Background Patients with repaired tetralogy of Fallot (rTOF) require lifelong surveillance with cardiovascular magnetic resonance (CMR) and cardiopulm...

Quantifying the oxygen preferences of bacterial communities using a metagenome-based approach

Oxygen is a primary driver of the distribution and activity of microbial life. Since oxygen levels are often difficult to measure in situ, one potenti...

Reprogramming BCMA-Targeted CAR-T Cells through γ-Secretase Modulation Blocks Antigen Shedding and Extends CAR-T Longevity

B-cell maturation antigen (BCMA) shedding by {gamma}-secretase generates soluble BCMA (sBCMA) , which diminishes membrane antigen density, and limits ...

Refining cardiometabolic risk assessment using MRI-derived pancreas volume and fat content: insights from the NAKO and UK Biobank

BackgroundThe pancreas is essential for metabolic homeostasis. Alterations in morphology and parenchymal integrity may impact proper function but are ...

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