Primary Care

Exercise & Fitness

Latest AI and machine learning research in exercise & fitness for healthcare professionals.

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Decoupling lactylation-associated metabolic remodelling in Asthma: Integrated multi-omics and machine learning identify RCC2 as a potential therapeutic target.

BACKGROUND: Aerobic glycolysis promotes lactate accumulation and histone lactylation (Kla), yet the cell-type-specific distribution of this axis and its link to metabolically stratified intercellular signalling in asthma remain poorly defined. We aimed to map lactate/Kla-associated metabolic states across airway lineages and develop an interpretable Lactate Metabolic Biomarker Diagnosis (LMBD) fra...

Apr 15 2026 42000636

Geometry-engineered hourglass-shaped cracks enable wide-linearity wearable strain sensors.

Flexible and stretchable strain sensors have attracted growing interest for applications in health monitoring and human-machine interfaces. Conventional crack-based resistive strain sensors can achieve high sensitivity and large strain ranges by exploiting the opening and closing of randomly distributed microcracks. However, the uncontrolled evolution of these cracks during prolonged use often lea...

Apr 14 2026 41979081
Nephrology: What You May Have Missed in 2025.

This article highlights some important nephrology studies published in 2025 that are relevant for many nonnephrologist physicians. Two studies examine...

Apr 14 2026 41974012
Analysis of B-Scan Ultrasonography Using Neural Networks to Predict Risk of Fibrosis in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).

OBJECTIVE: The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) continues to rise, underscoring the need for tools to st...

Apr 13 2026 42080324
Exploring learning motivation in the era of generative artificial intelligence among Chinese students majoring in translation and interpreting: A Q methodology study.

Generative artificial intelligence (GenAI) has brought significant while unpredictable changes to the learning motivation of students from various maj...

Apr 13 2026 41980457
Development and Validation of a Web Calculator for Predicting the Risk of Lower Limb Varicose Veins.

The aims of the present study were to develop and validate a predictive model for lower limb Varicose Veins, and to visualize the results using a web ...

Apr 13 2026 41974098
Topical review: Incorporating generative artificial intelligence into neuropsychology training: best practices, pitfalls, and recommendations for effective implementation.

OBJECTIVE: Generative artificial intelligence (AI) is rapidly transforming the field of neuropsychology by offering innovative opportunities to enhanc...

Apr 13 2026 41974113
Machine Learning to Predict Implant-Based Breast Reconstruction Failure: A Bootstrap-Validated Elastic Net Model.

BACKGROUND: Implant-based reconstruction failure remains a significant complication following breast reconstruction, with substantial implications for...

Apr 13 2026 41974903
Incremental value of deep learning denoising in low-dose coronary CT angiography in predominantly obese patients.

OBJECTIVE: To determine the added value of post-hoc convolutional neural network (CNN)-based denoising for low-radiation coronary CT angiography (CCTA...

Apr 12 2026 42001841
[Expert consensus on optimizing the multidisciplinary clinical pathways and management models for pulmonary function testing].

The promotion and application of pulmonary function tests (PFTs) in China have achieved preliminary success;however, numerous deficiencies persist in ...

Apr 12 2026 41912385
From Other Journals: A Review of Recent Articles by Our Editorial Team - 2026 First Edition.

In this review we provide a brief description of recently published articles addressing topics relevant to pediatric cardiologists. Our hope is to pro...

Apr 11 2026 41964871
Knowledge stickiness and technological concentration in the AI industry: an empirical study of Chinese cities.

The rapid diffusion of AI in China has proceeded to an uneven pace across cities. In this study we develop a motivation-resistance framework to help s...

Apr 11 2026 41965423
Using causal machine learning and real world data to improve dose response decision making for secukinumab in psoriatic arthritis.

Personalized treatment in psoriatic arthritis (PsA) remains challenging, particularly in guiding dose escalation decisions. We applied a causal machin...

Apr 11 2026 41965445
Explainable artificial intelligence models for accurate physical activity prediction using wearable device data.

OBJECTIVES: Wearable devices such as smartwatches are increasingly used for physical activity monitoring, but their proprietary algorithms often lack ...

Apr 10 2026 42000275
Neuroplasticity after Stroke: Adaptive and Maladaptive Mechanisms in Evidence-Based Rehabilitation.

BACKGROUND AND PURPOSE: Ischemic stroke remains a leading cause of long-term disability and persistent motor deficits. While neuroplasticity drives po...

Apr 10 2026 41967694
Factors influencing user adoption of AI painting tools based on the AIDUA model.

Artificial intelligence painting tools (AIPT) are increasingly integrated into creative practices, yet designers' willingness to adopt them remains un...

Apr 10 2026 41963482
Facilitators and barriers of research engagement in a large teaching hospital in the Netherlands: a narrative reflection.

BACKGROUND: Healthcare organisations are facing major challenges, including workforce shortages, rising costs, and an aging population. Research engag...

Apr 10 2026 41963960
Objective prediction of siesta based on machine learning and association with obesity.

OBJECTIVES: To predict siesta behavior using machine learning models trained on self-reported and objective data-temperature (T), activity (A), positi...

Apr 9 2026 41963146
Enabling ankle-brachial index prediction from doppler sounds using deep learning.

The ability to perform accurate point-of-care assessment of limb perfusion is critical for safe clinical decision-making. A formal ankle-brachial inde...

Apr 9 2026 41957436
Preoperative MRI-Derived Navigation Reduces Radiation Exposure in Pediatric Spinal Fusion.

BACKGROUND: Minimizing radiation exposure during pediatric spinal deformity correction is critical due to the cumulative lifetime effects of ionizing ...

Apr 9 2026 41949333
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