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Machine-learning derived identification of prognostic signature to forecast head and neck squamous cell carcinoma prognosis and drug response.

INTRODUCTION: Head and neck squamous cell carcinoma (HNSCC), a highly heterogeneous malignancy is of...

Catalpol promotes hippocampal neurogenesis and synaptogenesis in rats after multiple cerebral infarctions by mitochondrial regulation: involvement of the Shh signaling pathway.

INTRODUCTION: Ischemic stroke greatly threatens human life and health. Neuro-restoration is consider...

Bridging the gap in AI integration: enhancing clinician education and establishing pharmaceutical-level regulation for ethical healthcare.

Next-Gen Therapeutics: Pioneering Drug Discovery with iPSCs, Genomics, AI, and Clinical Trials in a Dish.

In the high-stakes arena of drug discovery, the journey from bench to bedside is hindered by a daunt...

Serum PD-1 regulation and PD-1 expression of CD4+Foxp3+ regulatory T cells in patients in thyroid eye disease associated with immunosuppression treatment.

PURPOSE: Thyroid eye disease (TED) primarily occurs in hyperthyroid patients, sometimes resulting in...

Ethical Application of Generative Artificial Intelligence in Medicine.

Generative artificial intelligence (AI) may revolutionize health care, providing solutions that rang...

Artificial Intelligence-Assisted Comparative Analysis of the Overlapping Molecular Pathophysiology of Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia.

The overlapping molecular pathophysiology of Alzheimer's Disease (AD), Amyotrophic Lateral Sclerosis...

Development and Clinical Validation of Visual Inspection With Acetic Acid Application-Artificial Intelligence Tool Using Cervical Images in Screen-and-Treat Visual Screening for Cervical Cancer in South India: A Pilot Study.

PURPOSE: The burden of cervical cancer in India is enormous, with more than 60,000 deaths being repo...

Stress testing deep learning models for prostate cancer detection on biopsies and surgical specimens.

The presence, location, and extent of prostate cancer is assessed by pathologists using H&E-stained ...

Integrating traditional QSAR and read-across-based regression models for predicting potential anti-leishmanial azole compounds.

Leishmaniasis, a neglected tropical disease caused by various Leishmania species, poses a significan...

Improved Fuzzy Cognitive Maps for Gene Regulatory Networks Inference Based on Time Series Data.

Microarray data provide lots of information regarding gene expression levels. Due to the large amoun...

Metaplasticity-Enabled Graphene Quantum Dot Devices for Mitigating Catastrophic Forgetting in Artificial Neural Networks.

The limitations of deep neural networks in continuous learning stem from oversimplifying the complex...

FormulationBCS: A Machine Learning Platform Based on Diverse Molecular Representations for Biopharmaceutical Classification System (BCS) Class Prediction.

The Biopharmaceutics Classification System (BCS) has facilitated biowaivers and played a significant...

Chemoenzymatic Synthesis Planning Guided by Reaction Type Score.

Thanks to the growing interest in computer-aided synthesis planning (CASP), a wide variety of retros...

AI-enabled clinical decision support tools for mental healthcare: A product review.

The review seeks to promote transparency in the availability of regulated AI-enabled Clinical Decisi...

Heparin in sepsis: current clinical findings and possible mechanisms.

Sepsis is a clinical syndrome resulting from the interaction between coagulation, inflammation, immu...

Predefined-Time Convergent Kinematic Control of Robotic Manipulators With Unknown Models Based on Hybrid Neural Dynamics and Human Behaviors.

This article proposes a model-free kinematic control method with predefined-time convergence for rob...

Needle in a haystack: Harnessing AI in drug patent searches and prediction.

The classification codes granted by patent offices are useful instruments for simplifying the bewild...

Hybrid CNN-GRU Model for Real-Time Blood Glucose Forecasting: Enhancing IoT-Based Diabetes Management with AI.

For people with diabetes, controlling blood glucose level (BGL) is a significant issue since the dis...

Translation as a Biosignature.

Life on Earth relies on mechanisms to store heritable information and translate this information int...

Accurate Spatial Heterogeneity Dissection and Gene Regulation Interpretation for Spatial Transcriptomics using Dual Graph Contrastive Learning.

Recent advances in spatial transcriptomics have enabled simultaneous preservation of high-throughput...