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Prognostication of Hepatocellular Carcinoma Using Artificial Intelligence.

Hepatocellular carcinoma (HCC) is a biologically heterogeneous tumor characterized by varying degrees of aggressiveness. The current treatment strategy for HCC is predominantly determined by the overall tumor burden, and does not address the diverse prognoses of patients with HCC owing to its heterogeneity. Therefore, the prognostication of HCC using imaging data is crucial for optimizing patient ...

Jun 1 2024 38807336

RepurposeDrugs: an interactive web-portal and predictive platform for repurposing mono- and combination therapies.

RepurposeDrugs (https://repurposedrugs.org/) is a comprehensive web-portal that combines a unique drug indication database with a machine learning (ML) predictor to discover new drug-indication associations for approved as well as investigational mono and combination therapies. The platform provides detailed information on treatment status, disease indications and clinical trials across 25 indicat...

May 23 2024 38980370
Exploring functional conservation in silico: a new machine learning approach to RNA-editing.

Around 50 years ago, molecular biology opened the path to understand changes in forms, adaptations, complexity, or the basis of human diseases through...

May 23 2024 38980372
Advanced Technologies in Radiation Research.

The U.S. Government is committed to maintaining a robust research program that supports a portfolio of scientific experts who are investigating the bi...

Apr 1 2024 38453643
Application and effectiveness of artificial intelligence for the border management of imported frozen fish in Taiwan.

In Taiwan, the number of applications for inspecting imported food has grown annually and noncompliant products must be accurately detected in these b...

Mar 15 2024 38526592
Pharmaceutical Decision Support System Using Machine Learning to Analyze and Limit Drug-Related Problems in Hospitals.

The health product circuit corresponds to the chain of steps that a medicine goes through in hospital, from prescription to administration. The safety...

Mar 1 2024 38426884
Automating the Identification of Safety Events Involving Machine Learning-Enabled Medical Devices.

With growing use of machine learning (ML)-enabled medical devices by clinicians and consumers safety events involving these systems are emerging. Curr...

Jan 25 2024 38269880
ASD2023: towards the integrating landscapes of allosteric knowledgebase.

Allosteric regulation, induced by perturbations at an allosteric site topographically distinct from the orthosteric site, is one of the most direct an...

Jan 5 2024 37870448
DrugBank 6.0: the DrugBank Knowledgebase for 2024.

First released in 2006, DrugBank (https://go.drugbank.com) has grown to become the 'gold standard' knowledge resource for drug, drug-target and relate...

Jan 5 2024 37953279
Investigations on druggable gene mutations related to AML/ALL lineage genes in Advanced Phases of CML: Implications in patient-tailored therapy of blast crisis CML in TKI era

Chronic Myeloid Leukemia (CML) is a myeloproliferative stem cell malignancy. Chronic Phase CML (CP-CML) is treatable with overall survival equivalent ...

Computational Protein Design - Where it goes?

Proteins have been playing a critical role in the regulation of diverse biological processes related to human life. With the increasing demand, functi...

Jan 1 2024 37272467
FDA Review of Radiologic AI Algorithms: Process and Challenges.

A Food and Drug Administration (FDA)-cleared artificial intelligence (AI) algorithm misdiagnosed a finding as an intracranial hemorrhage in a patient,...

Jan 1 2024 38165243
[Omics and cell controlling technology for drug discovery].

Knowledge Palette, Inc. is a start-up company that aims to overcome incurable diseases by applying the world's most accurate single-cell level and bul...

Jan 1 2024 38171839
Image-Based Subtype Classification for Glioblastoma Using Deep Learning: Prognostic Significance and Biologic Relevance.

PURPOSE: To apply deep learning algorithms to histopathology images, construct image-based subtypes independent of known clinical and molecular classi...

Jan 1 2024 38231003
Exploring the Potential of Artificial Intelligence in Breast Ultrasound.

Breast ultrasound has emerged as a valuable imaging modality in the detection and characterization of breast lesions, particularly in women with dense...

Jan 1 2024 38505878
Robotic Pills as Innovative Personalized Medicine Tools: A Mini Review.

The most common route for drug administration is the oral route due to the various advantages offered by this route, such as ease of administration, c...

Jan 1 2024 38841731
Graph Neural Networks with Multi-features for Predicting Cocrystals using APIs and Coformers Interactions.

INTRODUCTION: Active pharmaceutical ingredients (APIs) have gained direct pharmaceutical interest, along with their in vitro properties, and thus util...

Jan 1 2024 38847382
Leveraging Artificial Intelligence for Synergies in Drug Discovery: From Computers to Clinics.

Over the period of the preceding decade, artificial intelligence (AI) has proved an outstanding performance in entire dimensions of science including ...

Jan 1 2024 38874046
Artificial intelligence in diabetic retinopathy screening: from idea to a medical device in clinical practice.

With the growing significance of artificial intelligence in healthcare, new perspectives are emerging in primary care. Diabetic retinopathy, a microva...

Jan 1 2024 38981714
PD-1 Targeted Antibody Discovery Using AI Protein Diffusion.

The programmed cell death protein 1 (PD-1, CD279) is an important therapeutic target in many oncological diseases. This checkpoint protein inhibits T ...

Jan 1 2024 39228166
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