FDA General

Integrated computational screening of FDA-approved anticancer drugs as novel HPV-16 E6 inhibitors in cervical cancer.

Integrating Gait Analysis and AI Into Knee Osteoarthritis Care: Protocol for a 3-Phase Participatory Qualitative Study.

BACKGROUND: Knee osteoarthritis (OA) leads to pain, disability, and reduced quality of life. For advanced stages, knee arthroplasty surgery is the standard treatment, yet dissatisfaction and persistent mobility deficits remain common. Current surgical decision-making processes seldom incorporate objective predictors of outcomes, such as biomechanical data. Advances in computer vision, wearable sen...

An Explainable Artificial Intelligence Tool (FibroX) for Detecting Advanced Liver Fibrosis in Type 2 Diabetes: Protocol for a Pilot Crossover Trial.

BACKGROUND: Metabolic dysfunction-associated steatotic liver disease is highly prevalent in adults with type 2 diabetes, and advanced fibrosis is its ...

Imaging and genomics in stroke.

Imaging after ischemic and hemorrhagic stroke may allow measurement of key phenotypes of injury and recovery for which targeted therapies are still la...

3D printed drug delivery devices: recent promises and challenges.

INTRODUCTION: 3D Printing (3DP) has gained decent pace in the past decade in the pharmaceutical and biomedical fields. The approval of 3D-printed medi...

Artificial intelligence in microbiology: implications for metagenomics, diagnostics, and AMR surveillance.

Artificial intelligence (AI) is now a key player in modern microbiology, as it enables high-resolution analyses of genomic, metagenomic, and clinical ...

The power, potential of real-world data in randomized controlled trials: proceedings from a multistakeholder think tank.

Randomized controlled trials (RCTs) remain the gold standard for evaluating medical interventions, but they often face challenges related to patient r...

Print, check, repeat: digital quality by design for 3D-printed medicines using OpenAI models.

Semi-solid extrusion three-dimensional printing (SSE-3DP) technology has emerged as a versatile manufacturing approach across a wide array of industri...

Enhanced X-ray image denoising via the synergy of linear attention and convolution.

X-ray imaging technology, as the core non-invasive inspection method, plays an irreplaceable role in industrial non-destructive testing and medical di...

Composition, Pediatric Representation, and Transparency Disclosure Among FDA-Cleared Radiology Artificial Intelligence Products.

Effect of a mobile health intervention optimised with artificial intelligence on blood pressure and other cardiovascular risk factors in adults with high blood pressure: rationale and design of My Intelligent Cardiac Assistant (MICArdiac) randomised controlled trial.

INTRODUCTION: Control of blood pressure (BP) continues to be a challenge globally. Clinical trials have shown home BP monitoring and text-message inte...

Filament sensing tension: A bionic artificial tendon for self-force-regulated artificial muscle-driven wearable robotics.

Artificial muscles have been in development for decades and play a crucial role in the field of wearable robotics. However, a universal device for bot...

Establishing generalizability of wearable-enabled blood volume decompensation status estimation algorithms using transfer learning.

Timely assessment of blood volume decompensation status (BVDS) is essential for effective trauma intervention, especially in prehospital and resource-...

Opportunistic Screening on Chest CT, From the AJR Special Series on Screening.

The increase in chest CT volumes affords radiologists the opportunity to systematically assess imaging biomarkers, including coronary and thoracic art...

Validation of the parkland grading scale in predicting the critical view of safety during laparoscopic cholecystectomy: A prospective cohort study with implications for future artificial intelligence ground truth establishment.

BACKGROUNDS/AIMS: The critical view of safety (CVS) prevents bile duct injury, but severe inflammation hinders its achievement. This study evaluated t...

Development and cross-site validation of machine-learning models for diagnosis and prognosis of stable angina with and without obstructive coronary artery disease: a study protocol.

INTRODUCTION: Angina with no obstructive coronary artery disease (ANOCA) affects millions and is frequently under-recognised because diagnostic pathwa...

Predictive performance of artificial intelligence algorithms for gestational diabetes mellitus in pregnant women: a protocol for systematic review and meta-analysis.

BACKGROUND: Gestational diabetes mellitus (GDM) is a prevalent pregnancy complication that can pose numerous adverse health effects on both mothers an...

Synergistic Strategies in the Design of Dynamic Hydrogels: Lessons From the Hydrogen Bonding in the Nature.

Dynamic hydrogels face the challenge of balancing performance robustness with dynamic responsiveness, and traditional strategies often fail to address...

Bioinspired Dual-Scale Crack Manipulation Enabling 325%-Stretchable Metal Film Conductors for AI-Empowered Electronic Skins.

The advancement of electronic skins toward commercialization calls for cost-effective and robust flexible conductors, among which metal films are attr...

AI Breast Cancer Prediction Tool Hits the Clinic.

An artificial intelligence model called Clairity Breast, which uses mammogram images to predict the 5-year likelihood of breast cancer, was recently l...