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Mastering Complexity toward High-Performance Multi-Principal Element Alloy-Based Films and Coatings: A Review on Microstructural Regulation and Property Optimization.

Multi-principal element alloy (MPEA)-based films and coatings are redefining the boundaries of materials science, offering an unprecedented synergy of mechanical robustness, thermal stability, and chemical resilience. Their performance arises from intrinsic chemical complexity, such as high configurational entropy, lattice distortion, sluggish diffusion, and synergistic elemental interactions, ena...

Mar 23 2026 41870026

Deep learning-based identification of aberrant anterior tibial artery on knee MRI: a brazilian multicenter study.

OBJECTIVE: To develop and validate a deep learning model for the detection of aberrant anterior tibial artery (AATA) on axial T2-weighted knee MRI, given the surgical relevance of unrecognized AATA and the lack of automated detection tools. MATERIALS AND METHODS: This retrospective study included 70,260 MRI images from 2315 examinations (1441 without AATA and 874 with AATA) collected after institu...

Mar 23 2026 41870548
Mathematical Prediction Models for Sentinel Node Status in Early-Stage Breast Cancer: Protocol for a Systematic Review.

BACKGROUND: The status of the axilla remains a significant prognostic factor and influences adjuvant systemic and locoregional treatment choices in ea...

Mar 23 2026 41871336
A misclassification-aware explainable hybrid CNN-vision transformer framework for radiographic weld inspection.

Proper and valid identification of the defects in welding is also essential in the safety-critical manufacturing systems in order to maintain structur...

Mar 22 2026 41866427
Design of an in-pipe inspection robotic system (IPIRS) with YOLOv8-LSTM integration for real-time in-pipe navigation.

Conventional methods are still labor-intensive, hazardous, and have limited coverage, even though reliable pipeline inspection is crucial for oil, gas...

Mar 22 2026 41866593
The regulation of artificial intelligence in intensive care units: from narrow tools to generalist systems.

Artificial intelligence (AI) is increasingly explored for use in intensive care units. While most approved AI devices use narrow models, research is s...

Mar 21 2026 41865113
Regulation of calcium homeostasis by S100A12 drives NETosis in chronic kidney disease.

Chronic kidney disease (CKD) is characterized by persistent renal injury and inflammation. Although S100A12 is associated with inflammatory states, it...

Mar 21 2026 41862672
Repurposing Azilsartan medoxomil attenuates periodontitis by targeting SERPINB9 to promote apoptosis of IL1B+ macrophages.

Periodontitis (PD) is a common chronic inflammatory disease characterized by progressive destruction of periodontal tissues and is associated with sys...

Mar 20 2026 41864017
Contrasting roles of PD-L1 expression in tumor and stroma: Biological and prognostic implications in esophageal squamous cell carcinoma.

Programmed death-ligand 1 (PD-L1) plays a central role in immune regulation in esophageal squamous cell carcinoma (ESCC) and has been widely used as a...

Mar 20 2026 41859819
Advances and Perspectives in Graphene-Based Quantum Dots Enabled Neuromorphic Devices.

With the rapid rise in demand for artificial intelligence and brain-inspired computing, traditional von Neumann architecture is gradually approaching ...

Mar 20 2026 41861102
INTELCAPE: A Deep Learning-Powered System for Automated, High-Accuracy Crohn's Disease Diagnosis via Capsule Endoscopy.

BACKGROUND & AIMS: Capsule endoscopy (CE) is a noninvasive technique for diagnosing Crohn's disease (CD); however, manual interpretation of CE videos ...

Mar 19 2026 41861933
Bulliform cells: anatomical, physiological, genetic, and computational perspectives on plants' drought adaptation.

This work highlights pollen thermotolerance as vital for reproductive success under heat stress, integrating molecular regulation, gene mapping, and b...

Mar 19 2026 41857245
177Lu-PSMA dosimetry made easy: from theory to practical implementation.

177Lu-PSMA-targeted radioligand therapy (TRT) represents a major advance in managing metastatic castration-resistant prostate cancer (mCRPC), exploiti...

Mar 19 2026 41854638
Antibody-drug conjugate design and mechanisms of action for cancer treatment: state of the art and beyond.

Antibody-drug conjugates (ADCs) are a leading area of targeted cancer therapeutics, typically combining a tumour-associated antigen-specific antibody ...

Mar 19 2026 41855081
Energy-efficient path planning for Robotic Bulkhead Inspection using Residual-Enhanced UKF and Hierarchical MPC.

Ultrasonic thickness inspection of ship bulkheads poses significant challenges due to confined spaces, dynamic obstacles, and highly variable environm...

Mar 19 2026 41855236
Orthogonal disentanglement of single-cell multi-omics reveals private and shared drivers of tissue development and pathogenesis.

Characterizing gene expression and regulatory dynamics underlying both normal tissue function and disease progression requires an integrative analysis...

Mar 18 2026 41849387
Precision harvest: path to genetically modified organism-free crops with CRISPR by 2035.

Recent advances in clustered regularly interspaced short palindromic repeats (CRISPR) technology enable precise genetic modifications and produce gene...

Mar 18 2026 41856885
Approval of AI-Based Medical Devices in China From 2020 to 2025: Retrospective Analysis.

BACKGROUND: Artificial intelligence-based medical devices (AIMDs) have emerged as transformative technologies in modern health care. However, comprehe...

Mar 18 2026 41849560
Context-aware synthetic promoter design using neural networks enables rewiring of eukaryotic transcriptional networks.

Gene regulation through promoter engineering is a cornerstone of synthetic biology, enabling precise control over transcriptional networks. However, e...

Mar 17 2026 41844670
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