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Mechanistic insights into heart failure progression and therapeutic target discovery through plasma microRNA profiling: Findings from HOMAGE.

BACKGROUND: Identifying early pathobiological mechanisms associated with the onset and progression o...

Jan 2026 41592979
Advances in the pharmacology and mechanism of anti-skin aging in Tonifying Traditional Chinese Medicines.

ETHNOPHARMACOLOGICAL RELEVANCE: According to the Traditional Chinese Medicine (TCM) tenet that "inte...

Jan 2026 41592629
The predictive edge: modeling and simulation in drug product development.

It is well-known that drug development is challenging and a time- and resource-intensive endeavor. H...

Jan 2026 41592638
Sorafenib nanomedicine in HCC: nano-bio interactions and combination therapies.

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, with s...

Jan 2026 41578333
DualSightNet: A novel dual architecture for visual quality control of railway infrastructure.

To ensure the operational safety of trains, it is essential to monitor the condition of the rails. I...

Jan 2026 41576054
Interfacial Modification of Nanochannels for Enhanced Detection Accuracy in Complex Matrices.

Solid-state nanochannels, as an emerging single-molecule sensing platform, have shown great potentia...

Jan 2026 41572469
Recent advances in the analysis of the evolutionary RNA based therapeutics; a review.

The evolution of RNA-based therapies is bringing in a new era for the pharmaceutical industry. As a ...

Jan 2026 41580000
The effect of AI-assisted bedside echocardiography on inpatient care: a prospective trial.

AIMS: Focused cardiac ultrasound (FoCUS) can yield valuable information for decision-making. However...

Jan 2026 41640419
Integrative analysis identifies lactylation-related biomarkers in sepsis via bioinformatics and machine learning.

BACKGROUND: Protein lactylation is a novel post-translational modification driven by lactate and has...

Jan 2026 41570698
Patient perceptions and attitudes towards the use of artificial intelligence in the symptomatic breast unit.

OBJECTIVES: Artificial intelligence (AI) has been applied in a number of breast screening settings w...

Jan 2026 41565794
Digital horizons: Exploring the future of AI-enabled gastroenterology in the Kingdom of Saudi Arabia.

Artificial intelligence is rapidly reshaping gastroenterology through demonstrable gains in diagnost...

Jan 2026 41566344
Therapeutic nanofibrous scaffolds in precision drug delivery: formulation design, challenges and regulatory frameworks.

INTRODUCTION: Drug-loaded nanofibrous systems represent a breakthrough in drug delivery, overcoming ...

Jan 2026 41549842
Retinal Coronary Artery Calcium Scoring - A Scalable Tool for Life Insurers.

BACKGROUND.—: Cardiovascular risk estimation for life insurance underwriting relies on risk estimati...

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Jan 2026 41558685
Deep learning-based no-reference image quality assessment framework for Cryptosporidium spp. and Giardia spp.

Image Quality Assessment (IQA) plays a critical role in image-based decision-making systems, especia...

Jan 2026 41557673
Deep learning in stroke therapeutics: drug repurposing and beyond.

INTRODUCTION: Deep learning is reshaping stroke research by accelerating drug repurposing amid heter...

Jan 2026 41549848
Vascular cognitive impairment and dementia: Prevention, treatments, mechanisms and management options for the future.

Vascular Cognitive Impairment and Dementia (VCID), the second most common form of dementia, is becom...

Jan 2026 41554956
From Clusters to Outcomes: Machine Learning-Based Phenotyping in Intermediate-High-Risk Acute Pulmonary Embolism.

Intermediate-high-risk (IHR) pulmonary embolism (PE) represents a heterogeneous group in whom guidel...

Jan 2026 41555848
Multi-task non-contact ballistocardiogram-based vital signs monitoring in acupuncture.

The study introduces an innovative approach for efficient vital signs monitoring in acupuncture by c...

Jan 2026 41548353
Ethical and Regulatory Considerations for Artificial Intelligence Adoption in Craniofacial Surgery.

Artificial intelligence (AI) continues to enhance surgical care, with growing applications in cranio...

Jan 2026 41543479
Predicting the progression of difficult-to-treat rheumatoid arthritis by a machine learning scoring system, from the FIRST registry.

OBJECTIVES: This study aimed to develop and validate a prediction model for the future progression o...

Jan 2026 41545312
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