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Latest AI and machine learning research in fda general for healthcare professionals.

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Adding Artificial Intelligence to the PERT Improves Time to Diagnosis and Treatment of Pulmonary Embolism.

OBJECTIVES: There is limited data demonstrating the benefit of artificial intelligence technology in the diagnosis and triage of pulmonary embolism. Our study aims to demonstrate improved time to diagnosis of pulmonary embolism and subsequently time to anticoagulation and intervention with the goal of reducing in-hospital mortality. We hypothesized that implementation of artificial intelligence-as...

Aug 8 2026 42570761

Exploring patients' and public perspectives on an oral capsule for gastric submucosal delivery in Denmark and the USA: a mixed-methods study protocol.

INTRODUCTION: Oral capsules for gastric submucosal delivery represent a fundamentally new route of administration for biologics, which are currently limited to injection. Involving patients and members of the public to understand their perspectives on this novel pharmaceutical form, distinct from both injections and traditional oral tablets, is essential for the clinical development, regulatory ap...

Aug 7 2026 42567630
Conversational artificial intelligence HeAlth supporT in Atrial Fibrillation Self-Management (CHAT-AF-S): rationale and randomised controlled trial design.

INTRODUCTION: Atrial fibrillation (AF), a common arrhythmia, is associated with impaired quality of life and increased stroke risk and mortality. Clin...

Aug 7 2026 42567638
AI-Powered Automated Visual Inspection of IV Bags: A Real-World Case Study: Poster Presented at PDA Week 2026.

A high-volume IV bag line with variable printing faced ongoing false rejects, prompting deployment of an AI-powered automated visual inspection (AVI) ...

Aug 7 2026 42567646
Machine learning-guided QSAR screening of fluconazole analogs and FDA-approved drugs against Candida albicans, with docking, molecular dynamics, and ADMET analysis.

Invasive candidiasis caused by Candida albicans is a critical-priority fungal disease associated with high mortality, and the increasing resistance to...

Aug 7 2026 42568008
The complexity cliff in natural product discovery: why full automation remains elusive and the case for collaborative intelligence.

Covering: 1992 to 2025Natural products contribute to roughly half of FDA-approved small-molecule drugs, yet their discovery has remained surprisingly ...

Aug 6 2026 42559669
Uncovering the molecular landscape of young-onset diffuse gastric cancer: A relieff-based feature selection analysis on RNA-Seq data.

BACKGROUND: Diffuse Gastric Cancer (DGC) is an aggressive subtype with a poor prognosis and a lack of specific biomarkers, representing a critical unm...

Aug 6 2026 42561036
Diagnostic performance of FDA-cleared and CE-marked AI systems for mammography screening: a systematic review and meta-analysis.

OBJECTIVE: To evaluate the diagnostic performance of FDA/CE-cleared AI systems for mammography screening and assess their roles across clinical workfl...

Aug 5 2026 42561891
High-performance MXene/CuNWs/MH-TPU piezoresistive strain sensors fabricated via template-assisted phase separation with integrated thermal-EMI dual protection for emergency rescue.

In recent years, complex and extreme fire environments have posed a severe threat to the safety of front-line firefighters, urgently requiring high-pe...

Aug 5 2026 42555085
Evaluation of different defect-inspection setups for injection molding parts based on the deep learning method.

In the injection molding industry, the shift toward small-batch production has led to a greater variety of products and smaller batch sizes, necessita...

Aug 5 2026 42552322
See more, detect more: investigating colonic inspection techniques and polyp detection using machine learning.

BACKGROUND: Colorectal cancer (CRC) is a leading cause of cancer mortality despite widespread colonoscopy screening. Colonoscopy effectiveness, which ...

Aug 4 2026 42552483
The FERM guild: a differentially correlated microbial module drives hypertension via metabolic flux perturbations.

UNLABELLED: Hypertension is a major risk factor for cardiovascular diseases, with changes in gut microbiota composition and function being closely ass...

Aug 4 2026 42549911
Nurse-Led Large Language Model Chatbot for Predicting and Preventing Complications After Coronary Artery Bypass Grafting: Protocol for a Randomized Controlled Trial.

BACKGROUND: Thirty-day unplanned readmission following coronary artery bypass grafting (CABG) affects 10%-20% of patients and is a key quality indicat...

Aug 4 2026 42550966
Engineering principles in plant metabolism: integrating control, mechanics, and transport under dynamic environments.

Plant responses to dynamic environmental conditions remain challenging to describe within a unified mechanistic framework. This is largely because met...

Aug 3 2026 42544697
EEG-fMRI fusion-based source localization for the identification and mechanistic elucidation of paroxysmal kinesigenic dyskinesia.

UNLABELLED: Paroxysmal kinesigenic dyskinesia is a rare neurological disorder characterized by brief, recurrent motor attacks that significantly impai...

Aug 1 2026 42542675
A network approach with motion sequencing reveals hidden patterns of repetitive behavior in a pre-clinical model of epilepsy.

Epilepsy is the 4th most prevalent neurological condition with 50 million cases worldwide. Patients with epilepsy bare a disproportionate burden of co...

Aug 1 2026 42542112
Machine learning-assisted quorum sensing molecules regulate growth progression and bioactivity of an oxygenic photobiofilm for non-aeration greywater purification.

Microalgal-bacteria consortium provide self-aeration through photosynthetic oxygen production, offering an energy-efficient strategy for wastewater tr...

Aug 1 2026 42542140
In Vivo Assessment of Placental Structure and Perfusion in Late-Gestation Pregnancies and Their Association With Fetal Growth.

Adequate placental structure and function are crucial for fetal growth, while placental dysfunction often leads to fetal growth restriction (FGR), ass...

Aug 1 2026 42387322
Reference-Free large language model agents for physician-guided radiotherapy treatment planning.

BACKGROUND: Large language models (LLMs) have recently demonstrated exceptional capabilities, offering the potential to streamline workflows and enhan...

Aug 1 2026 42535478
From Small Data to Big Decisions: How Clinical Pharmacology Shapes Rare Disease Development.

Rare‑disease drug development is constrained by small and heterogeneous patient populations, limited natural‑history data, and the impracticality of l...

Aug 1 2026 42535720
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