FDA General

Artificial Intelligence in Dermatology: A Comprehensive Review of Approved Applications, Clinical Implementation, and Future Directions.

This comprehensive review examines artificial intelligence (AI) applications in dermatology, approve...

State of the Art on Inherited Retinal Dystrophies: Management and Molecular Genetics.

Inherited retinal dystrophies (IRDs) represent a group of heterogeneous disorders caused by gene mut...

Brain metabolic imaging-based model identifies cognitive stability in prodromal Alzheimer's disease.

The recent approval of anti-amyloid pharmaceuticals for the treatment of Alzheimer's disease (AD) ha...

The Lack of Neurofeedback Training Regulation Guidance and Process Evaluation May be a Source of Controversy in Post-Traumatic Stress Disorder-Neurofeedback Research: A Systematic Review and Statistical Analysis.

Neurofeedback (NF) based on brain-computer interface (BCI) is an important direction in adjunctive ...

Exon-intron boundary detection made easy by physicochemical properties of DNA.

Genome architecture in eukaryotes exhibits a high degree of complexity. Amidst the numerous intricac...

Hormonal regulation and expression dynamics of Bmp4 in the reproductive cycle of Pampus argenteus.

As a member of the bone morphogenetic protein (BMP) family, Bmp4 plays a crucial role in bone format...

Hypoferremic Response to Chronic Inflammation Is Controlled via the Hemojuvelin/Hepcidin/Ferroportin Axis and Does Not Involve Hepcidin-Independent Regulation of Fpn mRNA.

The iron regulatory hormone hepcidin contributes to the pathogenesis of anemia of inflammation (AI) ...

Absolute Quantitation of Neopterin as an Endogenous Pharmacodynamic Biomarker: The Successful Method Development, Validation, and Use of a Surrogate Matrix for Clinical Sample Analysis.

Biomarkers are playing an increasing role in the drug discovery and drug development process. Molecu...

A structured-illumination reflectance imaging dataset for woody breast assessment of broiler meat.

Wood breast (WB) myopathy is an economically important muscular defect that downgrades poultry meat ...

Labels as a feature: Network homophily for systematically annotating human GPCR drug-target interactions.

Machine learning has revolutionized drug discovery by enabling the exploration of vast, uncharted ch...

Cangrelor and AVN-944 as repurposable candidate drugs for hMPV: analysis entailed by AI-driven in silico approach.

Human metapneumovirus (hMPV) primarily causes respiratory tract infections in young children and old...

GRACE: Unveiling Gene Regulatory Networks With Causal Mechanistic Graph Neural Networks in Single-Cell RNA-Sequencing Data.

Reconstructing gene regulatory networks (GRNs) using single-cell RNA sequencing (scRNA-seq) data hol...

M3S-GRPred: a novel ensemble learning approach for the interpretable prediction of glucocorticoid receptor antagonists using a multi-step stacking strategy.

Accelerating drug discovery for glucocorticoid receptor (GR)-related disorders, including innovative...

Metabolomic signatures of pathogen suppression effect of Baltic eelgrass meadows in surrounding seawater.

Organic molecules exuded into water column by marine organisms represent a significant portion of ma...

Monitoring Amphetamine and Methamphetamine Mixtures Based on Deep Learning Involves Colorimetric Sensing.

Precise recognition and discrimination of highly similar analytes (either in structure or property) ...

Associations among white matter microstructural changes and the development of emotional reactivity and regulation in infancy.

Deficits in emotional reactivity and regulation assessed in infancy, including high levels of negati...

Nuciferine activates intestinal TAS2R46 to attenuate metabolic disorders and hyperlipidemia via hepatic VLDL regulation.

BACKGROUND: Dysregulated blood lipid metabolism, a primary driver of hyperlipidemia, is closely asso...

A measurement-based framework integrating machine learning and morphological dynamics for outdoor thermal regulation.

This study presents a comprehensive investigation into the interplay between machine learning (ML) m...

In-silico investigation integrated with machine learning to identify potential inhibitors targeting AKT2: Key driver of cancer cell progression and metastasis.

BACKGROUND AND OBJECTIVE: In search of a key driver for the invasive growth of cancer metastasis, AK...

Integrative neurorehabilitation using brain-computer interface: From motor function to mental health after stroke.

Stroke remains a leading cause of mortality and long-term disability worldwide, frequently resulting...

Overview of South Korean Guidelines for Approval of Large Language or Multimodal Models as Medical Devices: Key Features and Areas for Improvement.