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A High-Content Pseudotime Framework for Morphological Profiling of Dengue Virus Inhibitors from a Drug-Repurposing Library

Dengue virus (DENV) causes dengue fever, a globally prevalent, epidemic-prone disease with no FDA-ap...

(1)
An AI-Enabled Translational Drug Discovery Framework for NALCN Channelopathy: From High-Throughput Screening to Therapeutic Candidate

Background: More than 90% of rare diseases lack an approved therapy, partly reflecting economic barr...

(1)
Genotype-dependent behavioral signatures of opioid withdrawal revealed by automated behavioral quantification

Opioid withdrawal drives continued opioid use in opioid use disorder (OUD), which affected an estima...

CRT-HMAR: Causal Requirement Tracing-Guided Hierarchical Multi-Agent Regulation for Open-Task-Aware Infrared-Visible Image Fusion

Infrared and visible (IR-VIS) image fusion integrates complementary multimodal information into a si...

Epistemic Uncertainty-Aware Defect Detection for Quality Control in Medical Device Manufacturing

Objective: We investigate whether accounting for epistemic uncertainty can improve the reliability o...

Localize Any Object in X-Ray Security Scans without Human Annotation

Universal object localization in X-ray security inspection is critical for automated threat detectio...

Planner-Executor Style Multimodal Agentic System to Answer Patient Questions in Lung Cancer Screening CT

Background: Accurate patient understanding of lung cancer screening (LCS) results is critical for en...

DCM-SAM: Defect-Conditioned Mixture of LoRA Experts for NPU-Deployed AM Defect Segmentation

Metal additive manufacturing parts are inspected by X-ray computed tomography, where labelled data i...

Multi-Site Real-World Performance of Commercial AI for Pulmonary and Incidental Pulmonary Embolism Detection

Pulmonary embolism (PE) is a leading cause of cardiovascular mortality, yet the real-world performan...

Making Cross-Continental Federated Learning Repeatable with FLIP: a Multi-Application Study

Federated learning (FL) in healthcare remains challenging, as the overhead of rebuilding governance ...

BiomiX 3.0: A user-friendly platform for democratized multi-omics integration with graph-based learning.

Background Multi-omics integration has emerged as a powerful strategy to decode the molecular comple...

Satellite-gene abundance fusion reveals global hotspots of ocean ecosystem services

The Ocean sustains planetary health through climate regulation, biodiversity, and essential ecosyste...

Industrial Anomaly Detection via Defect-Grounded Reasoning in Visual Latent Space

Industrial anomaly detection (IAD) is evolving beyond conventional detection and localization toward...

A ready-to-deploy MLOps software platform for satellite and NEO detection at meter-class ground-based observatories

Ground-based astronomical observations frequently contain streaks produced by artificial satellites,...

ERPBench: A State-Grounded Evaluation Paradigm for Computer-Use Agents in Enterprise Software

Computer-use agents that operate through screenshots and simulated actions are advancing rapidly, ye...

Vision Transformer-Based Multi-Level Feature Fusion for Multi-Label Sewer Defect Classification

Automated classification of sewer defects is essential for infrastructure condition assessment and m...

A Transformer-Based Delta Expression Encoder for Psilocybin Transcriptional Response: Architecture, Representations, and Biological Validation

Understanding why individuals respond differently to psilocybin requires modeling the drug's transcr...

LUMANA: A Scenario-Based Field Validation of a Culturally Adapted AI System for Mental Health Screening in Sokoto State, Nigeria

Background: Mental health conditions represent a significant public health burden in sub-Saharan Afr...

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