Gastroenterology

Latest AI and machine learning research in gastroenterology for healthcare professionals.

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Artificial intelligence-based vascular pattern profiling predicts prognosis and therapeutic response in hepatocellular carcinoma.

BACKGROUND: Hepatocellular carcinoma (HCC) is characterized by active angiogenesis and heterogeneous vascular patterns. However, vascular pattern profiling in tumors and its clinical significance remain unexplored. OBJECTIVES: This study aimed to develop an artificial intelligence-based system for quantitative vascular pattern profiling in HCC and to investigate the associations between vascular p...

May 20 2026 42167651

Development and Validation of a Deep Learning-enabled Single Breath-hold Abbreviated MRI Protocol for Hepatocellular Carcinoma Diagnosis.

Purpose To develop a deep learning-enabled single breath-hold abbreviated MRI (DL-SBH-aMRI) protocol for hepatocellular carcinoma (HCC) diagnosis. Materials and Methods Patients at high risk of HCC from four institutions (January 2019-January 2025) were prospectively and retrospectively included. All patients underwent conventional complete MRI (cMRI) examinations including precontrast T1-weighted...

May 20 2026 42159476
Antibiotic therapy in febrile neutropenia in haematological patients: current considerations and future challenges.

The management of febrile neutropenia (FN) in oncohematological patients is undergoing a paradigm shift driven by a deeper understanding of patients' ...

May 20 2026 42159494
ToxiGuard: an AOP-guided mechanistically interpretable framework for multi-organ toxicity prediction.

Accurate prediction of organ-specific toxicity with mechanistic interpretability remains a central challenge in chemical safety assessment and transla...

May 20 2026 42159741
Preoperative prediction of tumor budding grade in rectal cancer by combining APT histogram analysis and ADC MRI.

OBJECTIVE: Tumor budding (TB) is a histopathological marker of aggressive behavior and poor prognosis in rectal cancer (RC), yet not reliably evaluate...

May 20 2026 42159837
Deep Learning Algorithm Based on Contrast-Enhanced Ultrasound Potentially Optimizes Treatment Strategies for Solitary Primary Hepatocellular Carcinoma.

OBJECTIVE: We aimed to propose a prognostic framework using a dual-branch Vision Transformer (ViT) deep learning (DL) architecture for stratifying rec...

May 20 2026 42161690
Enhancing esophageal cancer detection using a deep learning framework and a novel spectrum-aided vision enhancer for virtual narrow band imaging.

Esophageal cancer is a highly aggressive malignancy where early detection is critical for survival. However, early-stage lesions typically present sub...

May 20 2026 42162031
AI-driven volumetric approach for automatic chemotherapy response assessment in colorectal liver metastases.

OBJECTIVES: This study evaluates the clinical utility of an artificial intelligence (AI)-driven volumetric approach for assessing treatment response i...

May 20 2026 42162286
Habitat analysis and other AI technologies for Ki-67 prediction in hepatocellular carcinoma: a multi-center study.

OBJECTIVES: To develop various artificial intelligence (AI) models including radiomics, deep transfer learning (DTL) and habitat analysis models, as w...

May 19 2026 42157135
PancDS in Real-World Practice: A Prospective Multicenter Validation of a Clinical Decision-Support System Bridging Experience Gaps in Pancreatic Lesion Diagnosis.

Distinguishing pancreatic ductal adenocarcinoma (PDAC) from mass-forming pancreatitis (MFP) is challenging due to imaging mimicry and reader-dependent...

May 19 2026 42153997
Artificial intelligence-based anatomical recognition improves surgeon decision-making during robotic gastrectomy.

BACKGROUND: Artificial intelligence (AI)-based anatomical recognition has emerged to support intraoperative cognition; however, its clinical utility b...

May 19 2026 42154345
Interpretable multitask model for clinical pathology image prediction and interpretation.

Deep learning (DL)-based pathological image modelling and analysis approaches offer transformative potential for early cancer diagnostics, yet limited...

May 19 2026 42156411
HELIX: a scalable model for predicting context-dependent regulation of RNA splicing and isoform usage.

Context-dependent alternative splicing plays a critical role in disease pathogenesis and organ development, but its complex regulation remains challen...

May 19 2026 42156927
Deep learning-based prediction of lymph node metastasis and occult tumor cells in gastric cancer using histopathological images: a retrospective study.

BACKGROUND: Lymph node metastasis (LNM) is an important prognostic factor but is often underdiagnosed due to limitations in conventional assessment me...

May 19 2026 42156979
Precision nutrition for the prevention and management of inflammatory bowel disease.

The rising disease burden of inflammatory bowel disease (IBD) parallels the changing dietary landscape accompanying industrialization, underscoring th...

May 19 2026 42157016
An interpretable machine learning model integrating [18F]FDG PET/CT radiomics and clinical features for predicting perforation following chemotherapy in gastrointestinal lymphoma: a multicenter study.

BACKGROUND: Perforation following chemotherapy in gastrointestinal lymphoma (PFCGL) is a rare but severe and life-threatening complication. Early pre-...

May 19 2026 42151619
From histology to spatial transcriptomics: establishing a lightweight single-patch baseline.

Predicting spatial gene expression from hematoxylin and eosin (H&E)-stained histological images is a central challenge in the field of computational p...

May 18 2026 42151778
Classification of different light colors applied during the incubation period based on small intestine morphology with XGBoost algorithm.

BACKGROUND: Light is a significant environmental stimulus affecting embryonic development during incubation, and it is known that different wavelength...

May 18 2026 42151964
Artificial intelligence-assisted integrated care to promote colonoscopy uptakeĀ (AICC) in China: study protocol for a cluster randomized controlled trial.

BACKGROUND: Colorectal cancer (CRC) leads to heavy disease and economic burdens globally. Early screening such as colonoscopy has been demonstrated to...

May 18 2026 42152022
Diagnostic performance of artificial intelligence models in hepatocellular carcinoma: a systematic review and diagnostic meta-analysis.

OBJECTIVE: To systematically evaluate the diagnostic performance of artificial intelligence (AI) models for hepatocellular carcinoma (HCC) and to pool...

May 18 2026 42144587
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