Gastroenterology

Latest AI and machine learning research in gastroenterology for healthcare professionals.

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SCTA: An Agentic Framework for Stable and Interpretable Target Gene Discovery from Single-Cell RNA Sequencing

Identifying therapeutic target genes from single-cell RNA sequencing (scRNA-seq) data remains a fundamental challenge in translational biology. Unlike bulk assays, scRNA-seq captures heterogeneous cellular states and rare subpopulations, but this same heterogeneity makes target discovery highly sensitive to analytical choices throughout the pipeline, including preprocessing, cell population select...

Jul 26 2026 2607.23821v1

Bowel Obstruction Detection and Localization on Abdominal CT with Deep Learning

Bowel obstruction is a common and potentially life-threatening gastrointestinal condition. In the face of rising diagnostic workloads, the automated diagnosis of bowel obstruction on CT scans supports radiologists by accelerating detection and improving patient outcomes. In this work, we propose a deep learning framework with a multi-task objective that jointly detects bowel obstruction and locali...

Jul 24 2026 2607.22173v1
Diagnostic Performance of Fluorescence-Based Rapid On-Site Specimen Evaluation for Helicobacter pylori Antimicrobial Susceptibility Testing Before and After Algorithm Optimization: A Two-Round Comparative Study

Objective This study was designed to evaluate the diagnostic performance of fluorescence-based rapid on-site specimen evaluation (F-ROSE) for antimicr...

ASTRA-Net: Anatomy-Specific Transfer and Representation Alignment for Drug-Induced Sleep Endoscopy Segmentation

Quantitative drug-induced sleep endoscopy (DISE) requires reliable airway boundaries at specific anatomical levels. Pixel-level DISE annotations are s...

Jul 23 2026 2607.21370v1
Multicenter self-supervised computational pathology identifies prognostic histomorphological phenotypes in colorectal cancer

H&E whole-slide images capture prognostic information encoded in tumor morphology and the surrounding microenvironment, but these signals remain diffi...

Diagnostic Accuracy of MRI Radiomics for Predicting KRAS Mutation in Rectal Cancer: A Systematic Review and Meta-analysis

BackgroundKRAS mutation status is an important biomarker in rectal cancer, with implications for prognosis and treatment response. MRI-based radiomics...

Using binary silver labels in electronic health records-based computable phenotyping algorithms

Gold-standard phenotype labels are often unavailable at scale in electronic health record (EHR) studies because they require manual chart review. Weak...

Jul 20 2026 2607.18431v1
Vis2Reg: Visibility-Aware Landmark-Free Geometric 3D--2D Registration for Liver Laparoscopy

Accurate 3D--2D liver registration, which aligns preoperative 3D models to partial, view-dependent intraoperative surface observations, is critical fo...

Jul 20 2026 2607.17810v1
Measuring and Improving Complex-Atomic Answer Consistency in Endoscopic VQA

Endoscopic visual question answering (VQA) increasingly asks complex questions that combine several endoscopic answer components rather than isolated ...

Jul 20 2026 2607.17834v1
Induce to Empower: Improving Lightweight Baselines via Foundation Model Induction for Generalized Polyp Segmentation

Automated polyp segmentation in colonoscopy continues to pose challenges due to substantial appearance variations and indistinct polyp boundaries. Alt...

Jul 19 2026 2607.17208v1
Mapping Topic Change in Influential Hepatocellular Carcinoma Research: A Two-Cohort Bibliometric Analysis

The therapeutic landscape for hepatocellular carcinoma (HCC) is evolving rapidly, necessitating scalable approaches to synthesize the expanding scient...

Stitch-Inferencer: Enhance Endoscopic Video Segmentation and Tracking via Panoramic Reconstruction

Surgical video understanding is fundamental to navigation systems. Endoscopic perception is often hindered by a limited field-of-view and frequent ins...

Jul 16 2026 2607.14968v1
TCAM-Diff: Triplane-Aware Cross-Attention Medical Diffusion Model

We introduce TCAM-Diff, a novel 3D medical image generation model that reduces the memory requirements to encode and generate high-resolution 3D data....

Jul 15 2026 2607.13812v1
Virtual Chromoendscopy with Tunable Visibility Enhancement

Chromoendoscopy (CE) is a common clinical practice that sprays indigo carmine blue dye onto the gastric surface to improve the visibility of gastric l...

Jul 14 2026 2607.12416v1
MAGE: Color-Invariant and Spatial Knowledge Distillation for Gastric Neoplasm Classification

Accurate differentiation between gastric adenoma and carcinoma during endoscopy is critical for clinical decision-making. Yet, this task is highly cha...

Jul 14 2026 2607.12663v1
Learning from Complementary Ultrasound Representations for Liver Disease Classification

Differentiating non-alcoholic steatohepatitis (NASH) from non-alcoholic fatty liver disease (NAFLD) using ultrasound remains challenging due to subtle...

Jul 13 2026 2607.12062v1
Exploring Attitudes of Primary Caregivers Towards Pediatric Tissue-Based Research using Large Language Models: Insights from Rural and Urban Community Calls and Surveys

Objectives: Explore the perspectives of primary caregivers towards pediatric tissue-based research participation. Design: Cross-sectional. Setting: Tw...

Structure-guided design of a CD81-binding mini-protein that blocks hepatitis C virus entry

Despite the success of direct-acting antivirals, preventing hepatitis C virus (HCV) reinfection remains a critical global challenge. To address this, ...

Learned Immune Architectures of Durable Antibody Responses Across Vaccines

Vaccination is one of the most effective public health interventions. However, vaccine efficacy varies widely among individuals, as immunity arises fr...

Spatial Glyco-Codes Define Human Liver Pathology and Progression

Glycosylation is a fundamental process regulating cellular function, tissue organization, and disease progression. However, comprehensive glycan profi...

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