Gastroenterology

Latest AI and machine learning research in gastroenterology for healthcare professionals.

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GALAR-TemporalNet v2: Anatomy-Guided Dual-Branch Temporal Classification with Bidirectional Mamba and Dual-Graph GCN for Video Capsule Endoscopy -- after competition results

Video Capsule Endoscopy (VCE) poses a challenging multi-label temporal classification problem, requiring simultaneous localization of 8 anatomical regions and detection of 9 pathological findings across tens of thousands of frames. We present GALAR-TemporalNet v2, a hierarchical temporal model that addresses three core challenges: extreme class imbalance, long-range temporal dependencies, and path...

May 21 2026 2605.22209v1

VEELA: A Clinically-Constrained Benchmark for Liver Vessel Segmentation in Computed Tomography Angiography

Accurate segmentation of hepatic and portal vessels in contrast-enhanced computed tomography angiography (CTA) remains challenging due to complex vascular topology, peripheral visibility limitations, and acquisition-induced ambiguities. While existing public datasets offer valuable benchmarks, few include clinically realistic annotation constraints. We introduce VEELA (Vessel Extraction and Extric...

May 21 2026 2605.22357v1
Economic costing of evaluating, deploying and monitoring an artificial intelligence-based reconstruction for acceleration of rectal MRI examinations

Objectives: AI-based reconstructions can reduce MRI acquisition times and/or improve image quality. Guidelines recommend clinical evaluations and post...

Gut microbiota signatures differentiate trajectory-defined response phenotypes and predict self-management outcomes in irritable bowel syndrome

Background: Heterogeneity in symptom presentation and treatment response in irritable bowel syndrome (IBS) remains poorly understood. The gut microbio...

SurgLQA: Scalable Long-Horizon Surgical Video Question Answering

Surgical Video Question Answering (VideoQA) provides a promising paradigm for dynamic intraoperative interpretation, enabling real-time decision suppo...

May 18 2026 2605.17915v1
Overweight status drives early tumor microenvironment reprogramming in pancreatic ductal adenocarcinoma: a cell-type-resolved Bayesian hierarchical modeling and interactome analysis

Background: Obesity significantly increases the risk of prognosis and clinical outcomes in pancreatic ductal adenocarcinoma (PDAC). While research on ...

Testing the mutation accumulation hypothesis in aging with AlphaGenome

The mutation accumulation (MA) hypothesis posits that somatic mutations progressively escape selection and degrade tissue function during aging. Direc...

STOMAPY: Artificial Intelligence for Risk Stratification of Outcomes Requiring Enterostomal Therapy After Hospital Discharge Following Colorectal Surgery

Introduction: Infectious and wound-healing complications after colorectal surgery often increase the complexity of local care and the need for special...

Anatomy-Guided 3D Graph Networks for Couinaud Segmentation in Tumor Affected Livers

Abstract: Image-based liver Couinaud segmentation is designed to automatically provide the locations of suspicious objects in liver CT/MR images. Once...

Computational Imaging Priors for Wireless Capsule Endoscopy: Monte Carlo-Guided Hemoglobin Mapping for Rare-Anomaly Detection

Background. RGB-trained capsule-endoscopy classifiers underperform on small-vessel vascular findings by conflating hemoglobin contrast with bile and...

May 14 2026 2605.15062v1
Prediction of Rectal Cancer Regrowth from Longitudinal Endoscopy

Clinical trial studies indicate benefit of watch-and-wait (WW) surveillance for patients with rectal cancer showing a complete or near clinical respon...

May 13 2026 2605.12855v1
Contrastive Learning under Noisy Temporal Self-Supervision for Colonoscopy Videos

Learning robust representations of polyp tracklets is key to enabling multiple AI-assisted colonoscopy applications, from polyp characterization to au...

May 12 2026 2605.12320v1
Entropy Sorting Feature Selection: information-theoretic gene set identification improves single-cell RNA sequencing data interpretability

Single-cell RNA sequencing (scRNA-seq) has transformed our ability to resolve cellular heterogeneity, but extracting meaningful signals remains challe...

Pan-FM: A Pan-Organ Foundation Model with Saliency-Guided Masking for Missing Robustness

Foundation models (FMs) have shown great promise in medical imaging, but most FMs are trained on unimodal data within isolated domains, such as brain ...

May 8 2026 2605.07055v1
ChatIBD: design, safeguards, and early international use of a guideline-grounded generative AI tool for inflammatory bowel disease (IBD) professionals

Objectives To describe the design, operational safeguards, and early use of ChatIBD, a specialty-specific generative AI platform for inflammatory bowe...

Multi-LLM Disagreement as a Scalable Detector of Human Annotation Errors in Structured Data from Clinical Free-Text

Abstract Objective: Structured extraction from clinical free-text depends on human annotators whose labels are susceptible to errors and knowledge-dri...

Detection of Hepatocellular Carcinoma from B-Mode and Contrast-Enhanced Ultrasound Using a Dual-Path Convolutional Network

Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, with particularly severe consequences in sub-Saha...

immuneKG: An Immune-Cell-Aware Knowledge Graph Framework for Target Discovery in Immune-Mediated Diseases

Biomedical knowledge graphs have emerged as foundational infrastructure for AI-driven drug discovery, yet their translational impact on novel target i...

Biological Spatial Priors Regularize Foundation Model Representations for Cross-Site MSI Generalization in Colorectal Cancer

Predicting microsatellite instability (MSI) status from routine hematoxylin and eosin (H&E) whole slide images (WSIs) offers a practical alternative t...

May 4 2026 2605.02660v1
Early prediction of skeletal muscle loss using longitudinal clinical data in patients with gastric cancer after radical gastrectomy and adjuvant chemotherapy: a retrospective cohort study

Gastric cancer patients frequently experience skeletal muscle loss during the perioperative and adjuvant treatment period, which has been associated w...

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