Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Biotechnology advances and the parasitology paradigm: From genomes to multi-omics and translation.

Parasitic diseases impose a substantial and often underestimated burden on human and animal health, ...

Mar 2026 41628813
Building RNA Coarse-Grained Force Fields: Design Principles and Training Strategies.

The development of accurate and efficient computational models is essential for understanding RNA st...

Mar 2026 41877485
Research on Alzheimer's Disease Risk Assessment Models and Biomarker Screening Based on Bioinformatics Analysis and Machine Learning Algorithms.

INTRODUCTION: Alzheimer's Disease (AD) is among the most prevalent neurodegenerative disorders globa...

(1)
Mar 2026 41879435
Genome-wide detection of human 5' UTR variants that impact protein translation.

The 5' untranslated region (5' UTR) of messenger RNAs (mRNAs) plays a central role in regulating pro...

Mar 2026 41881026
A MULTIMODAL STOOL RNA, FIT AND MACHINE LEARNING CONCEPT FOR DETECTION OF ADVANCED PRECANCEROUS LESIONS AND COLORECTAL CANCER.

Accurate and effective early detection of colorectal cancer (CRC) and advanced precancerous lesions ...

Mar 2026 41873132
Identification of Novel Non-coding Genetic Variants of Serum Urate Using Whole Genome Sequencing in 7,339 Chinese.

OBJECTIVE: To investigate the genetic architecture of low-frequency and rare variants of serum urate...

(3)
Mar 2026 41873804
HiCMamba: Enhancing Hi-C resolution and identifying 3D genome structures with state space modeling.

Hi-C technology measures genome-wide interaction frequencies, providing a powerful tool for studying...

Mar 2026 41875404
HCLmNet: A unified hybrid continual learning strategy multimodal network for lung cancer survival prediction.

Lung cancer survival prediction remains one of the most challenging tasks in modern healthcare, as a...

Mar 2026 41875207
A heterogeneous graph neural network for candidate gene prediction in endometriosis.

OBJECTIVE: Precision medicine applications depend on elucidating the underlying molecular mechanisms...

Mar 2026 41881288
The Genetics of TDP-43 Type C Neurodegeneration: A Whole-Genome Sequencing Study and Literature Review.

BACKGROUND AND OBJECTIVES: Frontotemporal lobar degeneration TDP43 type C (TDP-C) is a rare and uniq...

Mar 2026 41883703
Machine learning derived ORC6 as a hub biomarker for predicting tumor microenvironment, prognoses, and therapeutic responses in lung adenocarcinoma.

The origin recognition complex (ORC) is a DNA-binding complex composed of six subunits involved in D...

Mar 2026 41875810
Interpretable learning of temporal cellular dynamics from single-cell data.

Reconstructing temporal cellular dynamics from static single-cell transcriptomics remains a major ch...

Mar 2026 41875867
A systems view on DNA damage response kinetics in Tetrahymena.

A tightly regulated DNA damage response is critical to the overall integrity of the genome. Here, we...

Mar 2026 41605654
Mapping the subgingival HerBiome and HisBiome over the human healthspan.

BACKGROUND: Understanding the intricate relationship between sex, age, and the oral microbiome is cr...

Mar 2026 41867064
ToxPLTC: Peptide Toxicity Prediction by Integrating Pretrained T5 Protein Language Model and Text Convolutional Neural Network.

Peptide-based therapeutics show promising potential in treating a range of diseases, such as diabete...

Mar 2026 41869759
Genomic Sequencing from Sanger to Next-Generation Sequencing: Historical Context, Comparative Advances, and Prospects for Next-Generation Phenomics.

DNA sequencing has revolutionized biological and biomedical research, offering profound insights int...

Mar 2026 41870192
Comprehensive multi omics profiling and Mendelian randomization assessment of lipid metabolites in lung cancer prognosis.

BACKGROUND: Lung cancer remains the leading cause of cancer-related mortality worldwide. This study ...

Mar 2026 41870745
The Synovial Fingerprint of Ankle Fractures: A Central Role for WNT Pathway Activation in Posttraumatic Ankle Osteoarthritis.

BACKGROUND: Osteoarthritis (OA) of the ankle is a disabling and understudied disease, most commonly ...

(3)
Mar 2026 41871107
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