Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Identification of potential riboswitch elements in Homo sapiens mRNA 5'UTR sequences using positive-unlabeled machine learning.

Riboswitches are a class of noncoding RNA structures that interact with target ligands to cause a co...

Apr 2025 40273288
The absence of both RIBC1 and RIBC2 induces decreased sperm motility and litter size in male mice.

BACKGROUND: RIBC1 (RIB43A domain with coiled-coils 1) and RIBC2 (RIB43A domain with coiled-coils 2) ...

Apr 2025 40265983
Development and validation of an interpretable machine learning model for diagnosing pathologic complete response in breast cancer.

BACKGROUND: Pathologic complete response (pCR) following neoadjuvant chemotherapy (NACT) is a critic...

Apr 2025 40318573
Harnessing genotype and phenotype data for population-scale variant classification using large language models and bayesian inference.

Variants of Uncertain Significance (VUS) in genetic testing for hereditary diseases burden patients ...

Apr 2025 40266329
Improved Pine Wood Nematode Disease Diagnosis System Based on Deep Learning.

Pine wilt disease caused by the pine wood nematode, , has profound implications for global forestry ...

Apr 2025 40267359
Clinical performance of a machine learning-based model for detecting lymph node metastasis in papillary thyroid carcinoma: A multicenter study.

Papillary thyroid carcinoma (PTC) is a common endocrine malignancy with a generally favorable progno...

Apr 2025 40265473
The inconsistent pathogenesis of endometriosis and adenomyosis: insights from endometrial metabolome and microbiome.

UNLABELLED: Endometriosis (EM) and adenomyosis (AM) are interrelated gynecological disorders charact...

Apr 2025 40261026
The prediction of RNA-small molecule binding sites in RNA structures based on geometric deep learning.

Biological interactions between RNA and small-molecule ligands play a crucial role in determining th...

Apr 2025 40268011
Transfer learning of multicellular organization via single-cell and spatial transcriptomics.

Biological tissues exhibit complex gene expression and multicellular patterns that are valuable to d...

Apr 2025 40258090
Breaking down data silos across companies to train genome-wide predictions: A feasibility study in wheat.

Big data, combined with artificial intelligence (AI) techniques, holds the potential to significantl...

Apr 2025 40253615
Predicting single-cell protein production from food-processing wastewater in sequencing batch reactors using ensemble learning.

Producing single-cell protein (SCP) from food-processing wastewater offers a sustainable approach to...

Apr 2025 40258495
Intersecting impact of CAG repeat and huntingtin knockout in stem cell-derived cortical neurons.

Huntington's Disease (HD) is caused by a CAG repeat expansion in the gene encoding huntingtin (HTT)....

Apr 2025 40258535
Intelligent Care: A Scientometric Analysis of Artificial Intelligence in Precision Medicine.

The integration of advanced computational methods into precision medicine represents a transformativ...

Apr 2025 40265391
Deep learning model based on ultrasound images predicts BRAF V600E mutation in papillary thyroid carcinoma.

BRAF V600E mutation status detection facilitates prognosis prediction in papillary thyroid carcinoma...

Apr 2025 40395668
Consecutive low-frequency shifts in A/T content denote nucleosome positions across microeukaryotes.

Nucleosomes are the basic repeating unit, each spanning ≈150bp, that structures DNA in the nucleus a...

Apr 2025 40491964
GRLGRN: graph representation-based learning to infer gene regulatory networks from single-cell RNA-seq data.

BACKGROUND: A gene regulatory network (GRN) is a graph-level representation that describes the regul...

Apr 2025 40251476
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