Latest AI and machine learning research in genetics for healthcare professionals.
Synthetic DNA offers significant benefits, remarkable information density and long-term stability for data storage. The practical success of DNA data storage, however, depends on solving the challenge of selective retrieval-accessing specific data with high fidelity from complex DNA mixtures. Here, we present a machine learning method to achieve high-fidelity, isothermal selective data retrieval f...
UNLABELLED: The gut virome is an emerging but underexplored component of the human microbiota, especially in pediatric Crohn's disease (CD). This study aimed to characterize the fecal virome in children with CD and evaluate its association with clinical response to infliximab (IFX) therapy. A total of 85 participants, including 60 pediatric CD patients and 25 healthy controls (HC), were recruited....
High-throughput, single-cell resolution profiling of neuronal activity is critical for understanding brain function and modeling neurological disorder...
A DNA-logic-gated, trimodal, self-powered biosensing platform is developed for the rapid, simultaneous, and on-site detection of two major sugarcane p...
The terms clonal monocytosis of undetermined significance (CMUS) and clonal cytopenia and monocytosis of undetermined significance (CCMUS) were introd...
Breast and ovarian cancers are still one of the most prevalent causes of cancer death among the women in all parts of the world, mostly occurring at a...
GenX (HFPO-DA), a short-chain per- and polyfluoroalkyl substance (PFAS) substitute, is implicated in testicular toxicity. GenX-related genes were inte...
OBJECTIVE: This study aimed to identify key mitochondria-related genes involved in the pathogenesis of osteoarthritis (OA). METHODS: Publicly availabl...
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiovascular disease. Recent metabolomics studies have revealed pathogeni...
Plastic pollution constitutes a critical environmental concern of this era, with synthetic polymers, i.e., polyethylene (PE), polyethylene terephthala...
Fungal biotechnology is crucial for generating high-value enzymes and fermentation products. Despite its industrial importance, major knowledge gaps i...
ETHNOPHARMACOLOGICAL RELEVANCE: Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by symptoms such as persistent diarrhea....
6PPD-quinone (6PPD-Q), a toxic tire-derived antioxidant transformation product, is a pervasive environmental contaminant linked to reproductive toxici...
Intratumoral cellular heterogeneity is a core challenge that drives drug resistance and hinders the advancement of precision oncology. Single-cell RNA...
Cancer remains a leading cause of global mortality, with early diagnosis being pivotal for improving treatment outcomes. Traditional tissue biopsy is ...
Pulmonary fibrosis (PF) is a progressive and fatal interstitial lung disease characterized by irreversible lung scarring and frequently associated wit...
Advanced differentiated thyroid cancer (DTC) is characterized by limited therapeutic options and unfavorable prognosis. To address this, we conduct pr...
BACKGROUND: Many individuals with bipolar disorder have decreased levels of cognitive functioning even when in a euthymic mood state. Persons with bip...
INTRODUCTION: . Pharmacological treatment is the mainstay in the acute and long-term management of severe mental disorders such as major depressive di...