Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Multiple generation distinct toxicant exposures induce epigenetic transgenerational inheritance of enhanced pathology and obesity.

Three successive multiple generations of rats were exposed to different toxicants and then bred to t...

Fungal and bacterial gut microbiota differ between colonization and infection.

The bacterial microbiota is well-recognized for its role in colonization and infection, while fung...

Toward three-dimensional DNA industrial nanorobots.

Nanoscale industrial robots have potential as manufacturing platforms and are capable of automatical...

Deep learning-enabled breast cancer endocrine response determination from H&E staining based on ESR1 signaling activity.

Estrogen receptor (ER) positivity by immunohistochemistry has long been a main selection criterium f...

The changing face of circulating tumor DNA (ctDNA) profiling: Factors that shape the landscape of methodologies, technologies, and commercialization.

Liquid biopsies, in particular the profiling of circulating tumor DNA (ctDNA), have long held promis...

GlAIcomics: a deep neural network classifier for spectroscopy-augmented mass spectrometric glycans data.

Carbohydrate sequencing is a formidable task identified as a strategic goal in modern biochemistry. ...

Comparison of hybrid RNA-based models to predict the degradation and mineralization of the microcontaminant hormone 17β-estradiol.

New alternatives for effluent decontamination, such as electrochemical oxidation, are being develope...

Classifying Alzheimer's disease and normal subjects using machine learning techniques and genetic-environmental features.

BACKGROUND: Alzheimer's disease (AD) is complicated by multiple environmental and polygenetic factor...

Self-supervised Learning for DNA sequences with circular dilated convolutional networks.

DNA molecules commonly exhibit wide interactions between the nucleobases. Modeling the interactions ...

m5UMCB: Prediction of RNA 5-methyluridine sites using multi-scale convolutional neural network with BiLSTM.

As a prevalent RNA modification, 5-methyluridine (mU) plays a critical role in diverse biological pr...

MEnTaT: A machine-learning approach for the identification of mutations to increase protein stability.

Enhancing protein thermal stability is important for biomedical and industrial applications as well ...

Validation of a Bacteriophage Hide Application to Reduce STEC in the Lairage Area of Commercial Beef Cattle Operations.

Finalyse, a T4 bacteriophage, is a pre-harvest intervention that utilizes a combination of bacteriop...

Learning massive interpretable gene regulatory networks of the human brain by merging Bayesian networks.

We present the Fast Greedy Equivalence Search (FGES)-Merge, a new method for learning the structure ...

Strengthening the Diagnosis of Drug-Resistant Tuberculosis Using NGS-Based Approaches and Bioinformatics Pipelines for Data Analysis in India.

In India, drug-resistant tuberculosis (DR-TB) is a major public health issue and a significant chall...

Reconstructing growth and dynamic trajectories from single-cell transcriptomics data.

Time-series single-cell RNA sequencing (scRNA-seq) datasets provide unprecedented opportunities to l...

Geometric Graph Learning to Predict Changes in Binding Free Energy and Protein Thermodynamic Stability upon Mutation.

Accurate prediction of binding free energy changes upon mutations is vital for optimizing drugs, des...

Personal transcriptome variation is poorly explained by current genomic deep learning models.

Genomic deep learning models can predict genome-wide epigenetic features and gene expression levels ...

Benchmarking of deep neural networks for predicting personal gene expression from DNA sequence highlights shortcomings.

Deep learning methods have recently become the state of the art in a variety of regulatory genomic t...

Frame-Level Teacher-Student Learning With Data Privacy for EEG Emotion Recognition.

Recently, electroencephalogram (EEG) emotion recognition has gradually attracted a lot of attention....

Frontiers in nonviral delivery of small molecule and genetic drugs, driven by polymer chemistry and machine learning for materials informatics.

Materials informatics (MI) has immense potential to accelerate the pace of innovation and new produc...

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