Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Replication of the Association between Retinal Aging Clock Susceptibility Genes and Retinal Age Gap in an Asian Population: The Nagahama Study.

PURPOSE: To replicate previously reported genetic associations for the retinal aging clock-quantifie...

Feb 2026 41958711
Identification of extracellular matrix stiffness-related genes in human scleral fibroblasts through bioinformatics analysis and machine learning.

BACKGROUND: Scleral extracellular matrix (ECM) remodeling plays a key role in myopia development. Th...

Feb 2026 41775226
Identification of key genes modules linking brain aging signatures and COVID-19-associated cognitive impairment.

BACKGROUND: Emerging evidence indicates that SARS-CoV-2 infection is associated with aging, particul...

Feb 2026 41763362
Computational dual-loop frameworks bridging single-enzyme design and cascade tunnel network engineering for next-generation biosynthetic systems.

Advances in computational biology are reshaping enzyme engineering from empirical practice into a pr...

Feb 2026 41763370
Harnessing exosomes for precision diagnostics and therapies in psychiatry disorders.

Exosomes are nanosized extracellular vesicles enriched with proteins, lipids, and nucleic acids and ...

(1)
Feb 2026 41763444
Harnessing AI to Decode Protein Kinases: Structural, Functional, and Therapeutic Design Perspectives.

Recent advances in Artificial Intelligence (AI) are reshaping kinase research by uncovering complex ...

Feb 2026 41763602
Signature-aware deep learning reveals distinct driver gene programs and mutational processes in glioblastoma and colon adenocarcinoma.

The precise identification of cancer driver mutations is essential for precision oncology; however, ...

Feb 2026 41764951
CXCL9 as a key feature for deep learning-based immune subtyping and prediction of immune checkpoint blockade response in triple-negative breast cancer.

BACKGROUND: Immune checkpoint blockade (ICB) therapy has provided a promising treatment option for p...

Feb 2026 41759266
Right and Left Atrial Dysfunction as Independent Cardiovascular Risk Factors: A UK Biobank Study.

BACKGROUND: Atrial cardiopathy often precedes atrial fibrillation (AF) and has emerged as an indepen...

(1)
Feb 2026 41744085
scDBic: A novel deep learning-based biclustering algorithm for analyzing scRNA-seq data.

MOTIVATION: Clustering single-cell RNA sequencing (scRNA-seq) data plays a vital role in the study o...

Feb 2026 41746287
Deep learning-assisted tumor radiomic dynamics on MRI predict pathological complete response in HCC undergoing immune-based therapy followed by hepatectomy.

BACKGROUND AIMS: Pathological complete response (pCR) following conversion therapy for initially unr...

Feb 2026 41746634
Population genomics reveals association of transposable elements variants with climatic adaptation in wild Amur grape.

Amur grape (Vitis amurensis Rupr.) is widely recognized for its cold tolerance traits and serves as ...

(1)
Feb 2026 41748614
Ryanodine receptor 2 mutations in catecholaminergic polymorphic ventricular tachycardia: From molecular mechanisms to precision medicine.

Catecholaminergic polymorphic ventricular tachycardia is a classic example of the successful transfe...

(1)
Feb 2026 41694040
Diverse database and machine learning model to narrow the generalization gap in RNA structure prediction.

Understanding macromolecular structures of proteins and nucleic acids is critical for discerning the...

Feb 2026 41739924
Targeting signaling pathways in lymphoma: From molecular mechanisms to clinical breakthroughs.

The treatment paradigm for lymphoma, a highly heterogeneous group of hematologic malignancies, has b...

Feb 2026 41736531
Progress toward real-world diagnostic applications of microfluidic paper-based analytical devices (μPADs).

Since their first report in 2007, microfluidic paper-based analytical devices (μPADs) have continued...

Feb 2026 41738441
Research trends of tumor-associated macrophages in colorectal cancer: a bibliometric analysis.

BACKGROUND: Colorectal cancer (CRC) represents the third most prevalent malignancy worldwide and acc...

Feb 2026 41738620
Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response.

Plasmid-mediated colistin resistance gene mcr has markedly diminished the effectiveness of colistin ...

Feb 2026 41739069
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