Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Deep Learning-Assisted Fluorescence Single-Particle Detection of Fumonisin B Powered by Entropy-Driven Catalysis and Argonaute.

Timely and accurate detection of trace mycotoxins in agricultural products and food is significant f...

Jan 2025 39868471
Identification of ubiquitination-related key biomarkers and immune infiltration in Crohn's disease by bioinformatics analysis and machine learning.

Crohn's disease (CD) is a chronic inflammatory bowel disease with an unknown etiology. Ubiquitinatio...

Jan 2025 39870856
Single-cell RNA sequencing and machine learning provide candidate drugs against drug-tolerant persister cells in colorectal cancer.

Drug resistance often stems from drug-tolerant persister (DTP) cells in cancer. These cells arise fr...

Jan 2025 39870146
Recipes and ingredients for deep learning models of 3D genome folding.

Three-dimensional genome folding plays roles in gene regulation and disease. In this review, we comp...

Jan 2025 39862604
Analysis of the genetic basis of fiber-related traits and flowering time in upland cotton using machine learning.

Cotton is an important crop for fiber production, but the genetic basis underlying key agronomic tra...

Jan 2025 39853381
Multiomic machine learning on lactylation for molecular typing and prognosis of lung adenocarcinoma.

To integrate machine learning and multiomic data on lactylation-related genes (LRGs) for molecular t...

Jan 2025 39856156
Alzheimer's Disease: Exploring Pathophysiological Hypotheses and the Role of Machine Learning in Drug Discovery.

Alzheimer's disease (AD) is a major neurodegenerative dementia, with its complex pathophysiology cha...

Jan 2025 39940772
Deciphering the role of metal ion transport-related genes in T2D pathogenesis and immune cell infiltration via scRNA-seq and machine learning.

INTRODUCTION: Type 2 diabetes (T2D) is a complex metabolic disorder with significant global health i...

Jan 2025 39926598
Immunolipid magnetic bead-based circulating tumor cell sorting: a novel approach for pathological staging of colorectal cancer.

OBJECTIVE: This study aimed to assess whether circulating tumor cells (CTCs) from colorectal cancer ...

Jan 2025 39927117
KanCell: dissecting cellular heterogeneity in biological tissues through integrated single-cell and spatial transcriptomics.

KanCell is a deep learning model based on Kolmogorov-Arnold networks (KAN) designed to enhance cellu...

Jan 2025 39577768
Advancing DNA Structural Analysis: A SERS Approach Free from Citrate Interference Combined with Machine Learning.

Surface-enhanced Raman spectroscopy (SERS) has become an indispensable tool for biomolecular analysi...

Jan 2025 39849911
Identification of potential biomarkers for 2022 Mpox virus infection: a transcriptomic network analysis and machine learning approach.

Monkeypox virus (MPXV), a zoonotic pathogen, re-emerged in 2022 with the Clade IIb variant, raising ...

Jan 2025 39848951
Identifying candidate RNA-seq biomarkers for severity discrimination in chemical injuries: A machine learning and molecular dynamics approach.

INTRODUCTION: Biomarkers play a crucial role across various fields by providing insights into biolog...

Jan 2025 39847951
Modeling gene interactions in polygenic prediction via geometric deep learning.

Polygenic risk score (PRS) is a widely used approach for predicting individuals' genetic risk of com...

Jan 2025 39562137
Inferring disease progression stages in single-cell transcriptomics using a weakly supervised deep learning approach.

Application of single-cell/nucleus genomic sequencing to patient-derived tissues offers potential so...

Jan 2025 39622637
Artificial intelligence and machine learning in cell-free-DNA-based diagnostics.

The discovery of circulating fetal and tumor cell-free DNA (cfDNA) molecules in plasma has opened up...

Jan 2025 39843210
Automated karyogram analysis for early detection of genetic and neurodegenerative disorders: a hybrid machine learning approach.

Anomalous chromosomes are the cause of genetic diseases such as cancer, Alzheimer's, Parkinson's, ep...

Jan 2025 39911161
Paying attention to the SARS-CoV-2 dialect : a deep neural network approach to predicting novel protein mutations.

Predicting novel mutations has long-lasting impacts on life science research. Traditionally, this pr...

Jan 2025 39838059
A scalable tool for analyzing genomic variants of humans using knowledge graphs and graph machine learning.

Advances in high-throughput genome sequencing have enabled large-scale genome sequencing in clinical...

Jan 2025 39906190
Genome-wide identification and expression analysis of phytochrome gene family in Aikang58 wheat ( L.).

Phytochromes are essential photoreceptors in plants that sense red and far-red light, playing a vita...

Jan 2025 39906238
Association of and gene polymorphisms and ERAP2 protein with the susceptibility and severity of rheumatoid arthritis in the Ukrainian population.

INTRODUCTION: Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects jo...

Jan 2025 39906739
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